(Q32884511)

11 July 2017

title

The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O⁶-methylguanine (English)

1 reference

11 July 2017

main subject

BCL2 antagonist/killer 1

1 reference

Sperm tail PG-rich repeat containing 1

1 reference

Checkpoint kinase 1

1 reference

positive regulation of mitochondrial membrane permeability involved in apoptotic process

1 reference

author name string

Ryosuke Fujikane

1

1 reference

11 July 2017

Masayuki Sanada

2

1 reference

11 July 2017

Mutsuo Sekiguchi

3

1 reference

11 July 2017

Masumi Hidaka

4

1 reference

11 July 2017

language of work or name

English

0 references

publication date

24 September 2012

1 reference

11 July 2017

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11 July 2017

volume

7

1 reference

11 July 2017

issue

9

1 reference

11 July 2017

page(s)

e44817

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Creative Commons Attribution 4.0 International

11 July 2017

copyright license

start time

24 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Different initial steps of apoptosis induced by two types of antineoplastic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

PCNA-MutSalpha-mediated binding of MutLalpha to replicative DNA with mismatched bases to induce apoptosis in human cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

O6-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Gene-trap mutagenesis: past, present and beyond

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Recent progress in the biology, chemistry and structural biology of DNA glycosylases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

The base excision repair pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Expression and cloning of complementary DNA for a human enzyme that repairs O6-methylguanine in DNA.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coli

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

A novel protein, MAPO1, that functions in apoptosis triggered by O6-methylguanine mispair in DNA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

The effect of O6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide, 1,3-bis(2-chloroethyl)1-nitrosourea, and cisplatin.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Molecular cloning and characterization of a complementary DNA encoding sperm tail protein SHIPPO 1.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Mechanisms of tolerance to DNA damaging therapeutic drugs

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Repair of O(6)-alkylguanine by alkyltransferases

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Methylnitrosourea-induced tumorigenesis in MGMT gene knockout mice.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Mitochondrial modifications during rat thymocyte apoptosis: a study at the single cell level.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Roles of transcription and repair in alkylation mutagenesis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454368

Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23028632

12 December 2020

inferred from PubMed ID database lookup

Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23028632

12 December 2020

inferred from PubMed ID database lookup

DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23028632

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0044817

1 reference

release_fywh4c5st5cexpmecm2itn5huu

11 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fywh4c5st5cexpmecm2itn5huu

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3454368

1 reference

11 July 2017

1 reference