(Q33274086)

25 July 2017

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title

The biological basis for modern treatment of chordoma (English)

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25 July 2017

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2

Michael D Cusimano

1 reference

25 July 2017

Roberto Jose Diaz

1

1 reference

25 July 2017

publication date

8 March 2011

1 reference

Journal of Neuro-Oncology

25 July 2017

published in

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25 July 2017

volume

104

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25 July 2017

issue

2

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25 July 2017

page(s)

411-422

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Chordoma: incidence and survival patterns in the United States, 1973-1995.

25 July 2017

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21 January 2018

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21 January 2018

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21 January 2018

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A multidisciplinary team approach to skull base chordomas

21 January 2018

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Chordomas and chondrosarcomas of the skull base: comparative analysis of clinical results in 30 patients

21 January 2018

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Chordomas of the craniocervical junction: follow-up review and prognostic factors

21 January 2018

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Intracranial chordomas: a clinicopathological and prognostic study of 51 cases

21 January 2018

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Chordoma of the skull base: predictors of tumor recurrence.

21 January 2018

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Chordoma: natural history and results in 28 patients treated at a single institution.

21 January 2018

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Surgery significantly improves survival in patients with chordoma

21 January 2018

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Proton radiation therapy for chordomas and chondrosarcomas of the skull base

21 January 2018

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Gamma Knife surgery for skull base chordomas and chondrosarcomas

21 January 2018

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Radiosurgery for chordomas and chondrosarcomas of the skull base

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordoma of the mobile spine. A clinicopathologic analysis of 40 patients

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Sacrococcygeal chordoma: review of 50 consecutive patients

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Clinical and imaging features of cervical chordoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordomas of the skull base: follow-up review and prognostic factors

21 January 2018

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Chordomas of the mediastinum: clinicopathologic, immunohistochemical, and ultrastructural study of six cases presenting as posterior mediastinal masses

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordoma: long-term follow-up after radical photon irradiation

21 January 2018

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Chordoma: A Clinicopathologic Study of Metastasis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordoma and chondrosarcoma: similar, but quite different, skull base tumors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

F-18 FDG PET/CT evaluation of sacrococcygeal chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Carbon-11-methionine positron emission tomography imaging of chordoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Base of skull chordoma. A correlative study of histologic and clinical features of 62 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Skull base and nonskull base chordomas: clinicopathologic and immunohistochemical study with special reference to nuclear pleomorphism and proliferative ability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Immunohistochemical comparison of chordoma with chondrosarcoma, myxopapillary ependymoma, and chordoid meningioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

The pathology of the human notochord

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

A molecular map of mesenchymal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

T-box genes in early embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Brachyury and chordoma: the chondroid-chordoid dilemma resolved?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Overexpressions of nerve growth factor and its tropomyosin-related kinase A receptor on chordoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Distinguishing benign notochordal cell tumors from vertebral chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Intraosseous benign notochordal cell tumours: overlooked precursors of classic chordomas?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Intraosseous benign notochord cell tumors (BNCT): further evidence supporting a relationship to chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Hedgehog signaling pathway and gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Prostate cancer and Hedgehog signalling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

The notochordal cell in the nucleus pulposus: a review in the context of tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

New candidate chromosomal regions for chordoma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Frequent deletion of the CDKN2A locus in chordoma: analysis of chromosomal imbalances using array comparative genomic hybridisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chromosome 7 abnormalities are common in chordomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Impact of cytogenetic abnormalities on the management of skull base chordomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Clinical outcome in chordoma: utility of flow cytometry in DNA determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

T (brachyury) gene duplication confers major susceptibility to familial chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Analysis of the fibroblastic growth factor receptor-RAS/RAF/MEK/ERK-ETS2/brachyury signalling pathway in chordomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Clonality studies in sacral chordoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Evaluation of 1p36 markers and clinical outcome in a skull base chordoma study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Mapping of candidate region for chordoma development to 1p36.13 by LOH analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CH1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordoma and chondrosarcoma gene profile: implications for immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Expression of matrix metalloproteinases-1, -2, and -9; tissue inhibitors of matrix metalloproteinases-1 and -2; cathepsin B; urokinase plasminogen activator; and plasminogen activator inhibitor, type I in skull base chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

MMP inhibition and downregulation by bisphosphonates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Molecular and biochemical analyses of platelet-derived growth factor receptor (PDGFR) B, PDGFRA, and KIT receptors in chordomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Differential expression of epidermal growth factor receptor, c-Met, and HER2/neu in chordoma compared with 17 other malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Expression of hepatocyte growth factor and c-MET in skull base chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Potential therapeutic targets for chordoma: PI3K/AKT/TSC1/TSC2/mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Response to erlotinib in a patient with treatment refractory chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Effectiveness of cetuximab/gefitinib in the therapy of a sacral chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Regression of cervical spinal cord compression in a patient with chordoma following treatment with cetuximab and gefitinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Targeting the molecular target of rapamycin (mTOR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Mechanisms of mammalian target of rapamycin inhibition in sarcoma: present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Sacrococcygeal chordomas in patients with tuberous sclerosis complex show somatic loss of TSC1 or TSC2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Upstream and downstream of mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Response to imatinib plus sirolimus in advanced chordoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

A novel target for treatment of chordoma: signal transducers and activators of transcription 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

The surgical management of sacral chordomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Long-term clinical outcomes following en bloc resections for sacral chordomas and chondrosarcomas: a series of twenty consecutive patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Patient outcome at long-term follow-up after aggressive microsurgical resection of cranial base chondrosarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordoma of the mobile spine: fifty years of experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Effectiveness and safety of spot scanning proton radiation therapy for chordomas and chondrosarcomas of the skull base: first long-term report

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordomas of the base of the skull and upper cervical spine. One hundred patients irradiated by a 3D conformal technique combining photon and proton beams

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Treatment of chordomas with CyberKnife: georgetown university experience and treatment recommendations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

The role of extracellular factors in human metastatic chordoma cell growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Effectiveness of carbon ion radiotherapy in the treatment of skull-base chordomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Phase II study of 9-nitro-camptothecin in patients with advanced chordoma or soft tissue sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Imatinib mesylate in chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Dedifferentiated chordoma. Response to aggressive chemotherapy in two cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chemotherapeutic treatment of malignant chordoma in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordoma: Natural history and treatment results in 33 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Direct intratumoral chemotherapy with carboplatin and epinephrine in a recurrent cervical chordoma: case report

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Hepatocyte growth factor activation inhibitors - therapeutic potential in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Novel therapeutic inhibitors of the c-Met signaling pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Retrospective long-term follow-up analysis in 21 patients with chordomas of various sites treated at a single institution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordoma of the spine above the sacrum. Treatment and outcome in 21 cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Skull base chordomas: a management challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Sacral chordoma: 40-year experience at a major cancer center

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Prognostic factors in chordoma of the sacrum and mobile spine: a study of 39 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Suboccipital and cervical chordomas: the value of aggressive treatment at first presentation of the disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Operative management of sacral chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Patient outcome at long-term follow-up after aggressive microsurgical resection of cranial base chordomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordomas of the skull base: surgical management and outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Skull base chordomas: efficacy of surgery followed by carbon ion radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Adjuvant radiation therapy and chondroid chordoma subtype are associated with a lower tumor recurrence rate of cranial chordoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Outcome of 132 operations in 97 patients with chordomas of the craniocervical junction and upper cervical spine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Chordoma of the mobile spine and sacrum: a retrospective analysis of a series of patients surgically treated at two referral centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Surgical margins and local control in resection of sacral chordomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Prognostic factors for long-term outcome of patients with surgical resection of skull base chordomas—106 cases review in one institution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0559-8

Kinetics of the immune response and regression of metastatic lesions following development of humoral anti-high molecular weight-melanoma associated antigen immunity in three patients with advanced malignant melanoma immunized with mouse antiidiotyp

21 January 2018

1 reference

12 December 2020

Developing c-MET pathway inhibitors for cancer therapy: progress and challenges

1 reference

12 December 2020

Scintigraphic features of primary sacral tumors

1 reference

12 December 2020

Primary tumors of the sacrum: diagnostic imaging

1 reference

12 December 2020

Expression of growth factors and structural proteins in chordomas: basic fibroblast growth factor, transforming growth factor alpha, and fibronectin are correlated with recurrence

1 reference

12 December 2020

Immunohistochemical analysis of receptor tyrosine kinase signal transduction activity in chordoma

1 reference

12 December 2020

Fractionated proton radiation therapy of cranial and intracranial tumors

1 reference

12 December 2020

Cutaneous metastasis of chordoma

1 reference

12 December 2020

Charged particles in radiation oncology

1 reference

12 December 2020

A clinicopathologic review of 25 cases of chordoma (a pleomorphic and metastasizing neoplasm).

1 reference

12 December 2020

Expression study of the target receptor tyrosine kinase of Imatinib mesylate in skull base chordomas

1 reference

12 December 2020

Does the tuberous sclerosis complex include clivus chordoma? A case report

1 reference

12 December 2020

Irradiation-induced angiogenesis through the up-regulation of the nitric oxide pathway: implications for tumor radiotherapy

1 reference

12 December 2020

Chordoma in the lateral medullary cistern in a patient with tuberous sclerosis: A case report and review of the literature

1 reference

12 December 2020

Assignment of the Hepatocyte Growth Factor (HGF) to chromosome 7q22-qter

1 reference

12 December 2020

Methylthioadenosine phosphorylase and activated insulin-like growth factor-1 receptor/insulin receptor: potential therapeutic targets in chordoma.

1 reference

12 December 2020

Chordomas of the skull base: MR features

1 reference

12 December 2020

Combination of PI3K/mTOR inhibition demonstrates efficacy in human chordoma.

1 reference

12 December 2020

Long-term control of clival chordoma with initial aggressive surgical resection and gamma knife radiosurgery for recurrence

1 reference

12 December 2020

Chordoma: clinical characteristics, management and prognosis of a case series of 25 patients

1 reference

12 December 2020

10.1007/S11060-011-0559-8

Identifiers

DOI

1 reference

Dimensions Publication ID

25 July 2017

1011700428

0 references

1 reference