(Q33346273)

26 July 2017

title

Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in Drosophila (English)

1 reference

26 July 2017

0 references

Garrett G Gross

1

1 reference

26 July 2017

R M Renny Feldman

2

1 reference

26 July 2017

Atish Ganguly

3

1 reference

26 July 2017

Jinhui Wang

4

1 reference

26 July 2017

Hong Yu

5

1 reference

26 July 2017

Ming Guo

6

1 reference

26 July 2017

language of work or name

English

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publication date

25 June 2008

1 reference

26 July 2017

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26 July 2017

volume

3

1 reference

26 July 2017

issue

6

1 reference

26 July 2017

page(s)

e2495

1 reference

Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

25 June 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression

21 June 2018

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Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease

21 June 2018

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A synthetic maternal-effect selfish genetic element drives population replacement in Drosophila

21 June 2018

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Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)

21 June 2018

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Drosophila in the study of neurodegenerative disease

21 June 2018

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Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion

21 June 2018

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Pathological and physiological functions of presenilins

21 June 2018

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Notch signalling: a simple pathway becomes complex

21 June 2018

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Caspase-dependent cell death in Drosophila

21 June 2018

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The X11/Mint family of adaptor proteins.

21 June 2018

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Presenilin-dependent gamma-secretase-mediated control of p53-associated cell death in Alzheimer's disease.

21 June 2018

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Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease

21 June 2018

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 June 2018

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Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664.

21 June 2018

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Drosophila models of neurodegenerative disease

21 June 2018

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APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

21 June 2018

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Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain

21 June 2018

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Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Family-based association between Alzheimer's disease and variants in UBQLN1

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

The genetics of cell death: approaches, insights and opportunities in Drosophila

21 June 2018

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The gamma-secretase complex: machinery for intramembrane proteolysis

21 June 2018

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Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

X11alpha impairs gamma- but not beta-cleavage of amyloid precursor protein.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

The role of presenilin cofactors in the gamma-secretase complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Results of a high-resolution genome screen of 437 Alzheimer's disease families

21 June 2018

1 reference

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Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Alzheimer's disease: genes, proteins, and therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

X11 alpha and x11 beta interact with presenilin-1 via their PDZ domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Notch signaling: cell fate control and signal integration in development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

21 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

21 June 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Control of daughter cell fates during asymmetric division: interaction of Numb and Notch

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Notch is required for successive cell decisions in the developing Drosophila retina.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

Reconstitution of gamma-secretase activity

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Amyloid precursor protein cytoplasmic domain antagonizes reelin neurite outgrowth inhibition of hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11alpha protein up-regulation in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

X11alpha modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the YENPTY sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Full genome screen for Alzheimer disease: Stage II analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Genetic association of ubiquilin with Alzheimer's disease and related quantitative measures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Association study of the Ubiquilin gene with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

ubiquilin antagonizes presenilin and promotes neurodegeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

A reporter for amyloid precursor protein gamma-secretase activity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Expression and characterization of the Drosophila X11-like/Mint protein during neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

The X11L/X11beta/MINT2 and X11L2/X11gamma/MINT3 scaffold proteins shuttle between the nucleus and cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

Fasciclin II signals new synapse formation through amyloid precursor protein and the scaffolding protein dX11/Mint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

The adaptor protein X11Lalpha/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002495

C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2429963

The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18575606

12 December 2020

inferred from PubMed ID database lookup

The Neuronal Adaptor Protein X11β Reduces Amyloid β-Protein Levels and Amyloid Plaque Formation in the Brains of Transgenic Mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18575606

12 December 2020

inferred from PubMed ID database lookup

Lack of association between UBQLN1 and Alzheimer disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18575606

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0002495

1 reference

release_favwtbmc5ne43huvoq7gkhegce

26 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/favwtbmc5ne43huvoq7gkhegce

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2429963

1 reference

26 July 2017

1 reference