(Q35968442)

11 August 2017

1 reference

title

The genetics of cell death: approaches, insights and opportunities in Drosophila (English)

1 reference

11 August 2017

0 references

1 reference

2

Jun R Huh

1 reference

11 August 2017

Bruce A Hay

1

1 reference

PubMed ID

15573123

11 August 2017

Ming Guo

series ordinal

3

1 reference

11 August 2017

1 December 2004

1 reference

11 August 2017

Nature Reviews Genetics

1 reference

11 August 2017

5

1 reference

11 August 2017

911-922

1 reference

11 August 2017

12

1 reference

https://scigraph.springernature.com/pub.10.1038/nrg1491

11 August 2017

0 references

cites work

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

Social controls on cell survival and cell death

21 January 2018

1 reference

How death shapes life during development

21 January 2018

1 reference

To kill or be killed: viral evasion of apoptosis

21 January 2018

1 reference

Manipulation of apoptosis in the host-parasite interaction

21 January 2018

1 reference

Apoptosis in the development and maintenance of the immune system

21 January 2018

1 reference

Mechanism, origin, and evolution of anoxia tolerance in animals

21 January 2018

1 reference

Apoptosis genes and autoimmunity.

21 January 2018

1 reference

Mitochondrion-mediated apoptosis in HIV-1 infection

21 January 2018

1 reference

Modelling neurodegenerative diseases in Drosophila: a fruitful approach?

21 January 2018

1 reference

Human neurodegenerative disease modeling using Drosophila.

21 January 2018

1 reference

Death to flies: Drosophila as a model system to study programmed cell death

21 January 2018

1 reference

Of flies and men--studying human disease in Drosophila

21 January 2018

1 reference

Cell death regulation in Drosophila: conservation of mechanism and unique insights

21 January 2018

1 reference

Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons

21 January 2018

1 reference

Insect transgenesis and its potential role in agriculture and human health

21 January 2018

1 reference

The art and design of genetic screens: Drosophila melanogaster

21 January 2018

1 reference

From sequence to phenotype: reverse genetics in Drosophila melanogaster

21 January 2018

1 reference

Gene expression systems in Drosophila: a synthesis of time and space.

21 January 2018

1 reference

Genome-wide RNAi analysis of growth and viability in Drosophila cells

21 January 2018

1 reference

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

21 January 2018

1 reference

bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

21 January 2018

1 reference

hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

21 January 2018

1 reference

The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

21 January 2018

1 reference

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

21 January 2018

1 reference

The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis

21 January 2018

1 reference

Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

21 January 2018

1 reference

The Drosophila Sterile-20 Kinase Slik Controls Cell Proliferation and Apoptosis during Imaginal Disc Development

21 January 2018

1 reference

Caspase Activity and a Specific Cytochrome C Are Required for Sperm Differentiation in Drosophila

21 January 2018

1 reference

Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization

21 January 2018

1 reference

Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role

21 January 2018

1 reference

A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration.

21 January 2018

1 reference

21 January 2018

1 reference

Ways of dying: multiple pathways to apoptosis.

21 January 2018

1 reference

Cytochrome C-mediated apoptosis

21 January 2018

1 reference

Constitutive expression of the machinery for programmed cell death

21 January 2018

1 reference

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

21 January 2018

1 reference

Genetics of programmed cell death in C. elegans: past, present and future.

21 January 2018

1 reference

Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4.

21 January 2018

1 reference

Many cuts to ruin: a comprehensive update of caspase substrates

21 January 2018

1 reference

Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

1 reference

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

Down-regulation of DIAP1 triggers a novel Drosophila cell death pathway mediated by Dark and DRONC.

21 January 2018

1 reference

The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC.

21 January 2018

1 reference

Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark

21 January 2018

1 reference

The role of ARK in stress-induced apoptosis in Drosophila cells

21 January 2018

1 reference

Mechanism of Dronc activation in Drosophila cells

21 January 2018

1 reference

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

21 January 2018

1 reference

Understanding IAP function and regulation: a view from Drosophila

21 January 2018

1 reference

Regulators of IAP function: coming to grips with the grim reaper

21 January 2018

1 reference

Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila.

21 January 2018

1 reference

Regulatory roles of JNK in programmed cell death

21 January 2018

1 reference

Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms.

21 January 2018

1 reference

Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition

21 January 2018

1 reference

GH3, a novel proapoptotic domain in Drosophila Grim, promotes a mitochondrial death pathway

21 January 2018

1 reference

Bifunctional killing activity encoded by conserved reaper proteins

21 January 2018

1 reference

Apoptosis: sculpture of a fly's head.

21 January 2018

1 reference

Transcriptional control of the core cell-death machinery

21 January 2018

1 reference

The Drosophila Hox gene deformed sculpts head morphology via direct regulation of the apoptosis activator reaper

21 January 2018

1 reference

Drosophila p53 binds a damage response element at the reaper locus

21 January 2018

1 reference

Ecdysone receptor directly binds the promoter of the Drosophila caspase dronc, regulating its expression in specific tissues

21 January 2018

1 reference

Caspase-independent cell engulfment mirrors cell death pattern in Drosophila embryos

21 January 2018

1 reference

Role of Bcl-2 family members in invertebrates

21 January 2018

1 reference

Eggs over easy: cell death in the Drosophila ovary

21 January 2018

1 reference

Autophagic programmed cell death in Drosophila

21 January 2018

1 reference

Dying for a cause: invertebrate genetics takes on human neurodegeneration

21 January 2018

1 reference

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

21 January 2018

1 reference

Limited role of developmental programmed cell death pathways in Drosophila norpA retinal degeneration.

21 January 2018

1 reference

The kinder side of killer proteases: caspase activation contributes to neuroprotection and CNS remodeling

21 January 2018

1 reference

Non-apoptotic functions of caspases in cellular proliferation and differentiation

21 January 2018

1 reference

Flying in the face of total disruption.

21 January 2018

1 reference

Dmp53 protects the Drosophila retina during a developmentally regulated DNA damage response

21 January 2018

1 reference

Reversible chromosome condensation induced in Drosophila embryos by anoxia: visualization of interphase nuclear organization

21 January 2018

1 reference

Nitric oxide-induced suspended animation promotes survival during hypoxia

21 January 2018

1 reference

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

21 January 2018

1 reference

Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila.

21 January 2018

1 reference

Coupling cell growth, proliferation, and death. Hippo weighs in.

21 January 2018

1 reference

Activation of the cAMP/PKA signaling pathway is required for post-ecdysial cell death in wing epidermal cells of Drosophila melanogaster

21 January 2018

1 reference

The identification of novel genes required for Drosophila anteroposterior axis formation in a germline clone screen using GFP-Staufen.

21 January 2018

1 reference

An F1 genetic screen for maternal-effect mutations affecting embryonic pattern formation in Drosophila melanogaster

21 January 2018

1 reference

Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1.

21 January 2018

1 reference

P element insertion-dependent gene activation in the Drosophila eye.

21 January 2018

1 reference

A modular misexpression screen in Drosophila detecting tissue-specific phenotypes

21 January 2018

1 reference

Drosophila Bruce can potently suppress Rpr- and Grim-dependent but not Hid-dependent cell death

21 January 2018

1 reference

Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis.

21 January 2018

1 reference

Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1.

21 January 2018

1 reference

Gene targeting by homologous recombination: a powerful addition to the genetic arsenal for Drosophila geneticists.

21 January 2018

1 reference

Mechanisms of gene silencing by double-stranded RNA

21 January 2018

1 reference

Functional dissection of an innate immune response by a genome-wide RNAi screen

21 January 2018

1 reference

Cell-biological applications of transfected-cell microarrays

21 January 2018

1 reference

Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.

21 January 2018

1 reference

Caspase-independent cell death?

21 January 2018

1 reference

Multiple cell death pathways as regulators of tumour initiation and progression.

21 January 2018

1 reference

A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster

21 January 2018

1 reference

A protein interaction map of Drosophila melanogaster

21 January 2018

1 reference

Inhibitor of apoptosis proteins physically interact with and block apoptosis induced by Drosophila proteins HID and GRIM.

21 January 2018

1 reference

Cell Death in Development

21 January 2018

1 reference

A matter of life and death

31 March 2020

1 reference

The strange case of the armored scale insect and its bacteriome

31 March 2020

1 reference

The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

31 March 2020

1 reference

Genetic control of programmed cell death in Drosophila

31 March 2020

1 reference

The head involution defective gene of Drosophila melanogaster functions in programmed cell death.

31 March 2020

1 reference

grim, a novel cell death gene in Drosophila

31 March 2020

1 reference

The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation

31 March 2020

1 reference

Drosophila immunity: paths and patterns

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1491

1 reference

11 August 2017

1 reference

PubMed ID

15573123