(Q33358637)

26 July 2017

Solving the puzzle of Parkinson's disease using induced pluripotent stem cells (English)

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26 July 2017

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8

Miguel A Esteban

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26 July 2017

Ping Zhao

1

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26 July 2017

Zhiwei Luo

2

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26 July 2017

Weihua Tian

3

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26 July 2017

Jiayin Yang

4

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26 July 2017

David P Ibáñez

5

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26 July 2017

Zhijian Huang

6

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26 July 2017

Micky D Tortorella

7

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26 July 2017

Wenxia Fan

9

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26 July 2017

17 June 2014

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Experimental Biology and Medicine

26 July 2017

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26 July 2017

239

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26 July 2017

11

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26 July 2017

1421-1432

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describes a project that uses

26 July 2017

induced pluripotent stem cell

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based on heuristic

inferred from title

cites work

Epidemiology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Staging of brain pathology related to sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Surgical management of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Genetics of Parkinson's disease--state of the art, 2013.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Recent advances in the genetics of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Parkinson's disease: insights from pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Neurotoxin-based models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Generation of human induced pluripotent stem cells from urine samples.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Progress made in the reprogramming field: new factors, new strategies and a new outlook

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Cellular reprogramming: a new approach to modelling Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Disease-specific induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Interplay of LRRK2 with chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Human iPSC-based modeling of late-onset disease via progerin-induced aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Genetic risk for Parkinson's disease correlates with alterations in neuronal manganese sensitivity between two human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Derivation of midbrain dopamine neurons from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using the bone morphogenic protein antagonist noggin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Small molecule modulation of Smoothened activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Investigating synapse formation and function using human pluripotent stem cell-derived neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Mechanisms and models of somatic cell reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Genetic and epigenetic variations in iPSCs: potential causes and implications for application

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Memory in induced pluripotent stem cells: reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

A functionally characterized test set of human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Erosion of dosage compensation impacts human iPSC disease modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Human induced pluripotent stem cells free of vector and transgene sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Opportunities and challenges of pluripotent stem cell neurodegenerative disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Glial degeneration and reactive gliosis in alpha-synucleinopathies: the emerging concept of primary gliodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Rapid single-step induction of functional neurons from human pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Environmental stress, ageing and glial cell senescence: a novel mechanistic link to Parkinson's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Cerebral organoids model human brain development and microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Remodeling neurodegeneration: somatic cell reprogramming-based models of adult neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370214538588

Induction of human neuronal cells by defined transcription factors

21 January 2018

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1038/NATURE10202

30 October 2021

Identifiers

DOI

10.1177/1535370214538588

1 reference

26 July 2017

1 reference