(Q33488925)

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Exploratory population pharmacokinetics (e-PPK) analysis for predicting human PK using exploratory ADME data during early drug discovery research

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Exploratory population pharmacokinetics (e-PPK) analysis for predicting human PK using exploratory ADME data during early drug discovery research (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Kenji Tabata

1

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Nozomu Hamakawa

2

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Seigo Sanoh

3

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Shigeyuki Terashita

4

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Toshio Teramura

5

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

publication date

1 April 2009

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

European Journal of Drug Metabolism and Pharmacokinetics

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

34

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

117-128

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Prediction of human clearance from animal data and molecular structural parameters using multivariate regression analysis

1 reference

https://api.crossref.org/works/10.1007%2FBF03191160

21 January 2018

Correlation between in-vitro microsomal enzyme activity and whole organ hepatic elimination kinetics: analysis with a dispersion model

1 reference

https://api.crossref.org/works/10.1007%2FBF03191160

21 January 2018

Prediction of human pharmacokinetics from animal data and molecular structural parameters using multivariate regression analysis: volume of distribution at steady state

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bayesian individualization of pharmacokinetics: simple implementation and comparison with non-Bayesian methods.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of oral absorption and bioavailablity of drugs between monkey and human

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prediction of drug metabolism, tissue distribution, and bioavailability of 50 structurally diverse compounds in rat using mechanism-based absorption, distribution, and metabolism prediction tools

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of gastrointestinal drug absorption in cynomolgus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological parameters in laboratory animals and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of human pharmacokinetics using physiologically based modeling: a retrospective analysis of 26 clinically tested drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Utility of physiologically based pharmacokinetic models to drug development and rational drug discovery candidate selection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism-based concepts of size and maturity in pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The absolute oral bioavailability of selected drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accuracy of allometrically predicted pharmacokinetic parameters in humans: role of species selection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel strategy for physiologically based predictions of human pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of metabolic drug clearance in humans: in vitro-in vivo extrapolation vs allometric scaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of intrinsic clearance of loxtidine from kinetic studies in rat, dog and human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polar molecular surface properties predict the intestinal absorption of drugs in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19645221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF03191160

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

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