(Q83204523)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16640456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

A novel strategy for physiologically based predictions of human pharmacokinetics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16640456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Hannah M Jones

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16640456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Neil Parrott

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16640456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Karin Jorga

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16640456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Thierry Lavé

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16640456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

1 January 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16640456%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacokinetics

20 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16640456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

45

1 reference

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20 January 2020

issue

5

1 reference

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20 January 2020

page(s)

511-542

1 reference

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Application of a generic physiologically based pharmacokinetic model to the estimation of xenobiotic levels in human plasma

20 January 2020

cites work

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Interspecies correlation of plasma concentration history of methotrexate (NSC-740)

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A comparison of physiochemical property profiles of development and marketed oral drugs

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12 December 2020

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12 December 2020

Incorporating measures of variability and uncertainty into the prediction of in vivo hepatic clearance from in vitro data

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12 December 2020

Man versus beast: pharmacokinetic scaling in mammals

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12 December 2020

Prediction of hepatic metabolic clearance based on interspecies allometric scaling techniques and in vitro-in vivo correlations

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12 December 2020

Use of a biophysical-kinetic model to understand the roles of protein binding and membrane partitioning on passive diffusion of highly lipophilic molecules across cellular barriers

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12 December 2020

Interspecies pharmacokinetic scaling of metazosin, a novel alpha-adrenergic antagonist

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12 December 2020

Biorelevant dissolution testing to predict the plasma profile of lipophilic drugs after oral administration

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12 December 2020

Physiological Parameter Values for Physiologically Based Pharmacokinetic Models

1 reference

12 December 2020

The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data.

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12 December 2020

Animal pharmacokinetics and interspecies scaling from animals to man of lamifiban, a new platelet aggregation inhibitor

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12 December 2020

Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism.

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12 December 2020

Physiologically based pharmacokinetic modeling 1: predicting the tissue distribution of moderate-to-strong bases.

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12 December 2020

Effect of fat tissue volume on the distribution kinetics of biperiden as a function of age in rats.

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12 December 2020

Prediction of hepatic metabolic clearance: comparison and assessment of prediction models

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12 December 2020

Physiological pharmacokinetics of ethoxybenzamide based on biochemical data obtained in vitro as well as on physiological data

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12 December 2020

Prediction of the pharmacokinetic parameters of reduced-dolasetron in man using in vitro-in vivo and interspecies allometric scaling.

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12 December 2020

Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes

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12 December 2020

Prediction of hepatic clearance from microsomes, hepatocytes, and liver slices

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12 December 2020

Forecasting the in vivo performance of four low solubility drugs from their in vitro dissolution data

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12 December 2020

Increased lipophilicity and subsequent cell partitioning decrease passive transcellular diffusion of novel, highly lipophilic antioxidants

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12 December 2020

Measurement of interstitial albumin in human skeletal muscle and adipose tissue by open-flow microperfusion

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12 December 2020

Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans.

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12 December 2020