(Q33508929)

27 July 2017

title

Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke (English)

1 reference

27 July 2017

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Cesar V Borlongan

10

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author name string

Noriyuki Matsukawa

1

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27 July 2017

Takao Yasuhara

2

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27 July 2017

Koichi Hara

3

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27 July 2017

Lin Xu

4

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27 July 2017

Mina Maki

5

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27 July 2017

Guolong Yu

6

1 reference

27 July 2017

Yuji Kaneko

7

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27 July 2017

Kosei Ojika

8

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27 July 2017

David C Hess

9

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27 July 2017

publication date

6 October 2009

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27 July 2017

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27 July 2017

volume

10

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27 July 2017

page(s)

126

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https://scigraph.springernature.com/pub.10.1186/1471-2202-10-126

27 July 2017

exact match

0 references

cites work

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Minocycline protects PC12 cells from ischemic-like injury and inhibits 5-lipoxygenase activation

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Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats

14 July 2018

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14 July 2018

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Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria

14 July 2018

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Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury

14 July 2018

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14 July 2018

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Regulation of chemokine receptor expression in human microglia and astrocytes

14 July 2018

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The yin and the yang of 5-lipoxygenase pathway activation

14 July 2018

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Protective effects of glial cell line-derived neurotrophic factor in ischemic brain injury

14 July 2018

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Delayed minocycline but not delayed mild hypothermia protects against embolic stroke

14 July 2018

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Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

14 July 2018

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Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia

14 July 2018

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Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.

14 July 2018

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Calcium antagonists for ischemic stroke: a systematic review

14 July 2018

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Reactive oxygen radicals in signaling and damage in the ischemic brain

14 July 2018

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14 July 2018

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Apoptosis in the nervous system

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Ions, cell volume, and apoptosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Reducing calcium overload in the ischemic brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Transplantation of cryopreserved human embryonal carcinoma-derived neurons (NT2N cells) promotes functional recovery in ischemic rats

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Testis-derived Sertoli cells have a trophic effect on dopamine neurons and alleviate hemiparkinsonism in rats

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Hypothermia and hyperbaric oxygen as treatment modalities for severe head injury

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Microglia potentiate damage to blood-brain barrier constituents: improvement by minocycline in vivo and in vitro.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Antioxidant properties of minocycline: neuroprotection in an oxidative stress assay and direct radical-scavenging activity

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Minocycline prevents glutamate-induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Minocycline worsens hypoxic-ischemic brain injury in a neonatal mouse model.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Rise and fall of minocycline in neuroprotection: need to promote publication of negative results

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Cooling for Acute Ischemic Brain Damage (COOL AID): a feasibility trial of endovascular cooling

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Optimal delivery of minocycline to the brain: implication for human studies of acute neuroprotection

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Nitric oxide-induced apoptosis is mediated by Bax/Bcl-2 gene expression, transition of cytochrome c, and activation of caspase-3 in rat vascular smooth muscle cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Suppression of cytochrome c release and apoptosis in testes with heat stress by minocycline

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Minocycline enhances MPTP toxicity to dopaminergic neurons

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Effects of minocycline alone and in combination with mild hypothermia in embolic stroke

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Minocycline blocks nitric oxide-induced neurotoxicity by inhibition p38 MAP kinase in rat cerebellar granule neurons

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Increased expression of hippocampal cholinergic neurostimulating peptide-related components and their messenger RNAs in the hippocampus of aged senescence-accelerated mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Prolonged expression of interferon-inducible protein-10 in ischemic cortex after permanent occlusion of the middle cerebral artery in rat.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762982

Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases

31 October 2018

1 reference

12 December 2020

Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species

1 reference

12 December 2020

Local immune responses in the rat cerebral cortex after middle cerebral artery occlusion

1 reference

12 December 2020

Glial cell survival is enhanced during melatonin-induced neuroprotection against cerebral ischemia

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2202-10-126

1 reference

Dimensions Publication ID

27 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2202-10-126

9 September 2019

1 reference

27 July 2017

1 reference