(Q33570384)

28 July 2017

Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury (English)

1 reference

28 July 2017

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Matthew N Rasband

6

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author name string

Dorothy P Schafer

1

1 reference

28 July 2017

Smita Jha

2

1 reference

28 July 2017

Fudong Liu

3

1 reference

28 July 2017

Trupti Akella

4

1 reference

28 July 2017

Louise D McCullough

5

1 reference

28 July 2017

language of work or name

English

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publication date

1 October 2009

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28 July 2017

Journal of Neuroscience

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28 July 2017

29

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28 July 2017

42

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28 July 2017

13242-13254

1 reference

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2801423/fullTextXML

inferred from PubMed Central ID database lookup

cites work

AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity.

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Remyelination in the CNS: from biology to therapy

21 June 2018

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The functional organization and assembly of the axon initial segment.

21 June 2018

1 reference

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Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

21 June 2018

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Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons

21 June 2018

1 reference

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K+ channels at the axon initial segment dampen near-threshold excitability of neocortical fast-spiking GABAergic interneurons

21 June 2018

1 reference

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Spectrin and ankyrin-based cytoskeletons at polarized domains in myelinated axons.

21 June 2018

1 reference

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Action potential generation requires a high sodium channel density in the axon initial segment

21 June 2018

1 reference

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Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene

21 June 2018

1 reference

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Mechanistic role of calpains in postischemic neurodegeneration

21 June 2018

1 reference

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Neurofascin assembles a specialized extracellular matrix at the axon initial segment

21 June 2018

1 reference

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Nodes of Ranvier and axon initial segments are ankyrin G-dependent domains that assemble by distinct mechanisms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

betaIV spectrin is recruited to axon initial segments and nodes of Ranvier by ankyrinG.

21 June 2018

1 reference

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Development of calpain-specific inactivators by screening of positional scanning epoxide libraries

21 June 2018

1 reference

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Specific role of the truncated betaIV-spectrin Sigma6 in sodium channel clustering at axon initial segments and nodes of ranvier

21 June 2018

1 reference

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Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton

21 June 2018

1 reference

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A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Excitatory effect of GABAergic axo-axonic cells in cortical microcircuits

21 June 2018

1 reference

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Developments in the design and synthesis of calpain inhibitors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Temporary focal ischemia in the mouse: technical aspects and patterns of Fluoro-Jade evident neurodegeneration.

21 June 2018

1 reference

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Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Estradiol regulates angiopoietin-1 mRNA expression through estrogen receptor-alpha in a rodent experimental stroke model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Adult neuron survival strategies--slamming on the brakes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Signaling mechanisms of the myelin inhibitors of axon regeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Neuroprotective effects of MK-801 in different rat stroke models for permanent middle cerebral artery occlusion: adverse effects of hypothalamic damage and strategies for its avoidance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Evaluation of the neuroprotective effects of sodium channel blockers after spinal cord injury: improved behavioral and neuroanatomical recovery with riluzole.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Brain ischemia and reperfusion: molecular mechanisms of neuronal injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

A survey of calpain inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

A diffusion barrier maintains distribution of membrane proteins in polarized neurons.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Proteolysis of erythrocyte-type and brain-type ankyrins in rat heart after postischemic reperfusion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Distribution of ankyrin isoforms and their proteolysis after ischemia and reperfusion in rat brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Microtubular proteolysis in focal cerebral ischemia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Development and therapeutic potential of calpain inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Brain fodrin: substrate for calpain I, an endogenous calcium-activated protease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

A selective filter for cytoplasmic transport at the axon initial segment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Neurofascin regulates the formation of gephyrin clusters and their subsequent translocation to the axon hillock of hippocampal neurons.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Clinical significance of alphaII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Action potential initiation and propagation in CA3 pyramidal axons.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Relative contributions of axonal and somatic Na channels to action potential initiation in cerebellar Purkinje neurons.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Site of action potential initiation in layer 5 pyramidal neurons.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Regenerating supernumerary axons are cholinergic and emerge from both autonomic and motor neurons in the rat spinal cord

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Infarct volume quantification in mouse focal cerebral ischemia: a comparison of triphenyltetrazolium chloride and cresyl violet staining techniques.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Does paranode formation and maintenance require partitioning of neurofascin 155 into lipid rafts?

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Accumulation of calpain and caspase-3 proteolytic fragments of brain-derived alphaII-spectrin in cerebral spinal fluid after middle cerebral artery occlusion in rats.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Microtubule-associated protein 2 (MAP2) associates with the NMDA receptor and is spatially redistributed within rat hippocampal neurons after oxygen-glucose deprivation.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

A targeting motif involved in sodium channel clustering at the axonal initial segment.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Calpains mediate p53 activation and neuronal death evoked by DNA damage.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Immunohistochemical and biochemical assessment of caspase-3 activation and DNA fragmentation following transient focal ischemia in the rat.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Regional vulnerability after traumatic brain injury: gender differences in mice that overexpress human copper, zinc superoxide dismutase

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

A microtiter trypan blue absorbance assay for the quantitative determination of excitotoxic neuronal injury in cell culture.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

Plasticity of Polarization: Changing Dendrites into Axons in Neurons Integrated in Neuronal Circuits

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801423

BetaIV spectrins are essential for membrane stability and the molecular organization of nodes of Ranvier

31 October 2018

1 reference

12 December 2020

Regeneration by supernumerary axons with synaptic terminals in spinal motoneurons of cats

1 reference

12 December 2020

Upregulation of calpain correlates with increased neurodegeneration in acute experimental auto-immune encephalomyelitis

1 reference

12 December 2020

A novel calpain inhibitor for the treatment of acute experimental autoimmune encephalomyelitis

1 reference

12 December 2020

10.1523/JNEUROSCI.3376-09.2009

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference