(Q35868063)

10 August 2017

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title

Adult neuron survival strategies--slamming on the brakes (English)

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10 August 2017

Susanna C Benn

1

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10 August 2017

Clifford J Woolf

series ordinal

2

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10 August 2017

language of work or name

English

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publication date

1 September 2004

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Nature Reviews Neuroscience

10 August 2017

published in

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10 August 2017

volume

5

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10 August 2017

issue

9

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10 August 2017

page(s)

686-700

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https://scigraph.springernature.com/pub.10.1038/nrn1477

10 August 2017

exact match

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cites work

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BAX is required for neuronal death after trophic factor deprivation and during development

21 January 2018

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Characterization of the execution pathway of developing motoneurons deprived of trophic support.

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Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

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Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

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Men are but worms: neuronal cell death in C elegans and vertebrates

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Neurotrophin signal transduction in the nervous system

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Cellular survival: a play in three Akts

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Dependence of postnatal motoneurones on their targets: review and hypothesis

21 January 2018

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Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival.

21 January 2018

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Upregulation of heat shock proteins rescues motoneurones from axotomy-induced cell death in neonatal rats

21 January 2018

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IAP family proteins delay motoneuron cell death in vivo

21 January 2018

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IAPs are essential for GDNF-mediated neuroprotective effects in injured motor neurons in vivo

21 January 2018

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Herpes simplex virus vector-mediated expression of Bcl-2 protects spinal motor neurons from degeneration following root avulsion

21 January 2018

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Programmed cell death in the developing nervous system

21 January 2018

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Delayed loss of spinal motoneurons after peripheral nerve injury in adult rats: a quantitative morphological study.

21 January 2018

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Apoptotic pathways: the roads to ruin

21 January 2018

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21 January 2018

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21 January 2018

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Fas ligand/Fas system in the brain: regulator of immune and apoptotic responses

21 January 2018

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Fas and Fas-L expression in Huntington's disease and Parkinson's disease

21 January 2018

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The soluble form of Fas molecule is elevated in parkinsonian brain tissues.

21 January 2018

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Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

21 January 2018

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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

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Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

21 January 2018

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TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

21 January 2018

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Adding facets to TNF signaling. The JNK angle

21 January 2018

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Tumor necrosis factor-alpha in normal and diseased brain: Conflicting effects via intraneuronal receptor crosstalk?

21 January 2018

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Adult human microglia secrete cytokines when exposed to neurotoxic prion protein peptide: no intermediary role for prostaglandin E2.

21 January 2018

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Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

21 January 2018

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TNF receptor subtype signalling: differences and cellular consequences

21 January 2018

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Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling.

21 January 2018

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TNF-R1 signaling: a beautiful pathway

21 January 2018

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Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

21 January 2018

1 reference

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

21 January 2018

1 reference

Glial cells in neurotoxicity development

21 January 2018

1 reference

ASK1 is essential for JNK/SAPK activation by TRAF2

21 January 2018

1 reference

AIP1: a new player in TNF signaling

21 January 2018

1 reference

A decision between life and death during TNF-alpha-induced signaling

21 January 2018

1 reference

Microglia in human immunodeficiency virus-associated neurodegeneration.

21 January 2018

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Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells

21 January 2018

1 reference

Bid, but not Bax, regulates VDAC channels.

21 January 2018

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21 January 2018

1 reference

Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

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Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

21 January 2018

1 reference

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.

21 January 2018

1 reference

Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization

21 January 2018

1 reference

Endonuclease G is an apoptotic DNase when released from mitochondria

21 January 2018

1 reference

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

21 January 2018

1 reference

NMDA receptor pathways as drug targets

21 January 2018

1 reference

Localization of nitric oxide synthase indicating a neural role for nitric oxide

21 January 2018

1 reference

Role and regulation of p53 in depolarization-induced neuronal death.

21 January 2018

1 reference

Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels

21 January 2018

1 reference

Coupling endoplasmic reticulum stress to the cell death program

21 January 2018

1 reference

A trip to the ER: coping with stress

21 January 2018

1 reference

Roles of CHOP/GADD153 in endoplasmic reticulum stress

21 January 2018

1 reference

Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades

21 January 2018

1 reference

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

1 reference

Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

21 January 2018

1 reference

Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

21 January 2018

1 reference

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

21 January 2018

1 reference

Programmed cell death of embryonic motoneurons triggered through the Fas death receptor

21 January 2018

1 reference

Active killing of neurons during development and following stress: a role for p75(NTR) and Fas?

21 January 2018

1 reference

21 January 2018

A convoluted way to die.

1 reference

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

21 January 2018

1 reference

Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.

21 January 2018

1 reference

FADD: A link between TNF family receptors and caspases in Parkinson's disease

21 January 2018

1 reference

Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease.

21 January 2018

1 reference

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

21 January 2018

1 reference

Death receptors on reactive astrocytes: a key role in the fine tuning of brain inflammation?

21 January 2018

1 reference

Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates

21 January 2018

1 reference

Neurogenesis and apoptotic cell death.

21 January 2018

1 reference

Mitochondrial uncoupling protein 2 in the central nervous system: neuromodulator and neuroprotector

21 January 2018

1 reference

UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells

21 January 2018

1 reference

Inhibition of death receptor signals by cellular FLIP

21 January 2018

1 reference

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

21 January 2018

1 reference

MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly

21 January 2018

1 reference

A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes

21 January 2018

1 reference

An alternatively spliced long form of Fas apoptosis inhibitory molecule (FAIM) with tissue-specific expression in the brain.

21 January 2018

1 reference

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

21 January 2018

1 reference

Prevention of constitutive TNF receptor 1 signaling by silencer of death domains

21 January 2018

1 reference

Tumor necrosis factor receptor 1 is an ATPase regulated by silencer of death domain

21 January 2018

1 reference

New insights in the role of Bcl-2 Bcl-2 and the endoplasmic reticulum

21 January 2018

1 reference

The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum

21 January 2018

1 reference

Endoplasmic reticulum membrane-sorting protein of lymphocytes (BAP31) is highly expressed in neurons and discrete endocrine cells

21 January 2018

1 reference

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

21 January 2018

1 reference

Stress-induced decrease in TRAF2 stability is mediated by Siah2

21 January 2018

1 reference

Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death

21 January 2018

1 reference

NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis

21 January 2018

1 reference

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

21 January 2018

1 reference

IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition

21 January 2018

1 reference

Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1

21 January 2018

1 reference

Inhibition of Daxx-mediated apoptosis by heat shock protein 27

21 January 2018

1 reference

Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm

21 January 2018

1 reference

Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death

21 January 2018

1 reference

Hsp72 and stress kinase c-jun N-terminal kinase regulate the bid-dependent pathway in tumor necrosis factor-induced apoptosis

21 January 2018

1 reference

Hsp72 functions as a natural inhibitory protein of c-Jun N-terminal kinase

21 January 2018

1 reference

Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation

21 January 2018

1 reference

Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

1 reference

Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27.

21 January 2018

1 reference

Crosstalk between p38, Hsp25 and Akt in spinal motor neurons after sciatic nerve injury

21 January 2018

1 reference

Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways

21 January 2018

1 reference

ORP150 protects against hypoxia/ischemia-induced neuronal death

21 January 2018

1 reference

ORP150/HSP12A regulates Purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development

21 January 2018

1 reference

Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways

21 January 2018

1 reference

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

21 January 2018

1 reference

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

1 reference

Ku70 suppresses the apoptotic translocation of Bax to mitochondria.

21 January 2018

1 reference

hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria

21 January 2018

1 reference

Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis

21 January 2018

1 reference

Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance

21 January 2018

1 reference

Superoxide activates mitochondrial uncoupling proteins

21 January 2018

1 reference

Mitochondria, Ca2+ and neurodegenerative disease

21 January 2018

1 reference

Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts

21 January 2018

1 reference

Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

21 January 2018

1 reference

Mitochondria in cell death: novel targets for neuroprotection and cardioprotection

21 January 2018

1 reference

Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury.

21 January 2018

1 reference

BMCP1: a mitochondrial uncoupling protein in neurons which regulates mitochondrial function and oxidant production

21 January 2018

1 reference

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

21 January 2018

1 reference

Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3

21 January 2018

1 reference

A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis

21 January 2018

1 reference

Calpain and caspase: can you tell the difference?

21 January 2018

1 reference

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

21 January 2018

1 reference

Boo, a novel negative regulator of cell death, interacts with Apaf-1.

21 January 2018

1 reference

Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1

21 January 2018

1 reference

Permanent cerebral ischemia induces sustained procaspase 9L increase not controlled by Bcl-2.

21 January 2018

1 reference

Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin

21 January 2018

1 reference

Hsp27 negatively regulates cell death by interacting with cytochrome c.

21 January 2018

1 reference

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

21 January 2018

1 reference

Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90

21 January 2018

1 reference

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

21 January 2018

1 reference

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

21 January 2018

1 reference

Heat-shock protein 70 antagonizes apoptosis-inducing factor

21 January 2018

1 reference

The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

21 January 2018

1 reference

Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis

21 January 2018

1 reference

Natural cellular inhibitors of caspases

21 January 2018

1 reference

Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells

21 January 2018

1 reference

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

21 January 2018

1 reference

Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

21 January 2018

1 reference

Motoneuron resistance to apoptotic cell death in vivo correlates with the ratio between X-linked inhibitor of apoptosis proteins (XIAPs) and its inhibitor, XIAP-associated factor 1.

21 January 2018

1 reference

RING finger proteins: mediators of ubiquitin ligase activity

21 January 2018

1 reference

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

21 January 2018

1 reference

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

21 January 2018

1 reference

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

1 reference

Roles of the metallothionein family of proteins in the central nervous system

21 January 2018

1 reference

Growth inhibitory factor prevents neurite extension and the death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging

21 January 2018

1 reference

Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat

21 January 2018

1 reference

Role of neurotrophic factors in motoneuron development

21 January 2018

1 reference

Cell death during development of the nervous system

21 January 2018

1 reference

Widespread elimination of naturally occurring neuronal death in Bax-deficient mice

31 March 2020

1 reference

Neurotrophins support the development of diverse sensory axon morphologies.

31 March 2020

1 reference

Neonatal sciatic nerve transection induces TUNEL labeling of neurons in the rat spinal cord and DRG

31 March 2020

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Axotomy-induced neuronal death during development

31 March 2020

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IAP family proteins--suppressors of apoptosis

31 March 2020

1 reference

Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.

31 March 2020

1 reference

Adult spinal motoneurons remain viable despite prolonged absence of functional synaptic contact with muscle

31 March 2020

1 reference

Delayed loss of small dorsal root ganglion cells after transection of the rat sciatic nerve

31 March 2020

1 reference

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

31 March 2020

1 reference

31 March 2020

1 reference

A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis

31 March 2020

1 reference

Tumor necrosis factor-alpha at the crossroads of neuronal life and death during HIV-associated dementia

31 March 2020

1 reference

Therapeutic potential of anti-inflammatory drugs in focal stroke

31 March 2020

1 reference

Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway

31 March 2020

1 reference

Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways.

31 March 2020

1 reference

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

31 March 2020

1 reference

Control of mitochondrial permeability by Bcl-2 family members

31 March 2020

1 reference

Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease

31 March 2020

1 reference

Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore

31 March 2020

1 reference

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

31 March 2020

1 reference

Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis

31 March 2020

1 reference

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

31 March 2020

1 reference

Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP

31 March 2020

1 reference

Neurotrophin signalling pathways regulating neuronal apoptosis

31 March 2020

1 reference

Neurotrophins live or let die: does p75NTR decide?

31 March 2020

1 reference

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

31 March 2020

1 reference

Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis

31 March 2020

1 reference

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

31 March 2020

1 reference

Fas/tumor necrosis factor receptor death signaling is required for axotomy-induced death of motoneurons in vivo

31 March 2020

1 reference

Induction of apoptosis signal regulating kinase 1 (ASK1) after spinal cord injury in rats: possible involvement of ASK1-JNK and -p38 pathways in neuronal apoptosis

31 March 2020

1 reference

Cellular FLICE-inhibitory protein: an attractive therapeutic target?

31 March 2020

1 reference

Killer wiles: growing interest in Fas

31 March 2020

1 reference

Fas engagement induces neurite growth through ERK activation and p35 upregulation

31 March 2020

1 reference

FAP-1: a protein tyrosine phosphatase that associates with Fas

31 March 2020

1 reference

X-linked inhibitor of apoptosis protein activates the phosphatidylinositol 3-kinase/Akt pathway in rat granulosa cells during follicular development

31 March 2020

1 reference

Expression of TAK1, a mediator of TGF-β and BMP signaling, during mouse embryonic development

31 March 2020

1 reference

Hsp27 as a negative regulator of cytochrome C release

31 March 2020

1 reference

Mitochondria, AIF and caspases--rivaling for cell death execution.

31 March 2020

1 reference

Prevention of apoptotic neuronal death by controlling procaspases? A point of view

31 March 2020

1 reference

31 March 2020

Controlling cell death

1 reference

Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO

31 March 2020

1 reference

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRN1477

1 reference

Dimensions Publication ID

10 August 2017

1042351136

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