(Q33580123)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

main subject

DNA damage

0 references

reactive oxygen species

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Lorenzo Bombardelli

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

M C. Mione

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Marzia Fumagalli

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Vassilis Gorgoulis

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Fabrizio Daddadifagagna

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

author name string

M Ogrunc

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

M Liontos

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

publication date

28 February 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

9 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

page(s)

998-1012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

9 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4013514/fullTextXML

inferred from PubMed Central ID database lookup

cites work

ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation

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IL1- and TGFβ-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine 'bystander senescence'.

14 July 2018

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Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration

14 July 2018

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ROS-generating oxidases Nox1 and Nox4 contribute to oncogenic Ras-induced premature senescence

14 July 2018

1 reference

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Repair or regenerate--how can we tip the balance?

14 July 2018

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Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

14 July 2018

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14 July 2018

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Aiding and abetting roles of NOX oxidases in cellular transformation

14 July 2018

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Production and detection of reactive oxygen species (ROS) in cancers

14 July 2018

1 reference

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ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

14 July 2018

1 reference

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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

14 July 2018

1 reference

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Checks and balances: interplay of RTKs and PTPs in cancer progression

14 July 2018

1 reference

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Never-ageing cellular senescence

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Hallmarks of Cancer: The Next Generation

14 July 2018

1 reference

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The essence of senescence

14 July 2018

1 reference

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Small-Molecule Inhibitors of NADPH Oxidase 4

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Redox metabolism and malignancy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Constitutive NADPH-dependent electron transferase activity of the Nox4 dehydrogenase domain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

The senescence-associated secretory phenotype: the dark side of tumor suppression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

p53--a Jack of all trades but master of none

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Mutational analysis reveals distinct features of the Nox4-p22 phox complex

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Living on a break: cellular senescence as a DNA-damage response

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Oncogene addiction versus oncogene amnesia: perhaps more than just a bad habit?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

An oncogene-induced DNA damage model for cancer development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Cellular senescence: when bad things happen to good cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

14 July 2018

1 reference

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

BRAFE600-associated senescence-like cell cycle arrest of human naevi

14 July 2018

1 reference

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Tumour biology: senescence in premalignant tumours

14 July 2018

1 reference

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

ONCOMINE: a cancer microarray database and integrated data-mining platform

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Reactive oxygen species in oncogenic transformation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Oxidative DNA damage: mechanisms, mutation, and disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Molecular mechanisms of N-acetylcysteine actions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Prevention of lung cancer: summary of published evidence.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Gemcitabine: progress in the treatment of pancreatic cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

DNA damage-dependent nuclear dynamics of the Mre11 complex

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Signaling from Ras to Rac and beyond: not just a matter of GEFs

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Cell transformation by the superoxide-generating oxidase Mox1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Creation of human tumour cells with defined genetic elements

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

A Rac1 effector site controlling mitogenesis through superoxide production

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Lovastatin inhibits pancreatic cancer growth regardless of RAS mutation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Cell cycle-dependent variations in the distribution of the nuclear protein cyclin proliferating cell nuclear antigen in cultured cells: subdivision of S phase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Production of large amounts of hydrogen peroxide by human tumor cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Oncogene-induced senescence as an initial barrier in lymphoma development

14 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.16

Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.16

Requirement for Rac1 in a K-ras induced lung cancer in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.16

Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.16

Rac1 GTPase regulates cell genomic stability and senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.16

N-acetil-l-cysteine and 2-amino-2-thiiazoline N-acetyl-l-cysteinate as a possible cancer chemopreventive agents in murine models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.16

First-line treatment for advanced pancreatic cancer. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013514

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24583638

12 December 2020

inferred from PubMed ID database lookup

Molecular pathogenesis of pancreatic cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24583638

12 December 2020

inferred from PubMed ID database lookup

Complex engagement of DNA damage response pathways in human cancer and in lung tumor progression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24583638

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/CDD.2014.16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

24583638

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24583638%20AND%20SRC:MED&resulttype=core&format=json