(Q39198938)

English

IL1- and TGFβ-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine 'bystander senescence'.

scientific article published on December 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

IL1- and TGFβ-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine 'bystander senescence'. (English)

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

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3

object named as

Jiri Bartek

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

author name string

Sona Hubackova

1

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Katerina Krejcikova

2

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Zdenek Hodny

4

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Europe PubMed Central

PMC publication ID

9 September 2017

publication date

1 December 2012

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Europe PubMed Central

PMC publication ID

9 September 2017

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

4

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

12

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

932-951

1 reference

Europe PubMed Central

PMC publication ID

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

15 June 2018

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

15 June 2018

Upregulation of Nox4 by TGF{beta}1 oxidizes SERCA and inhibits NO in arterial smooth muscle of the prediabetic Zucker rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

15 June 2018

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

The NADPH oxidase Nox4 and aging in the heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Cytokines shape chemotherapy-induced and 'bystander' senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Tumor stroma-derived TGF-beta limits myc-driven lymphomagenesis via Suv39h1-dependent senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

High resolution imaging of changes in the structure and spatial organization of chromatin, gamma-H2A.X and the MRN complex within etoposide-induced DNA repair foci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Up-regulation of ROS by mitochondria-dependent bystander signaling contributes to genotoxicity of bystander effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

NADPH oxidases 1 and 4 mediate cellular senescence induced by resveratrol in human endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Interferon-gamma induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Overexpression of human NOX1 complex induces genome instability in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Interleukin-1 and nitric oxide increase NADPH oxidase activity in human coronary artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Reducing mammary cancer risk through premature stem cell senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Subcytotoxic H2O2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Microarray analysis of replicative senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Altered expression of plasminogen activator and plasminogen activator inhibitor during cellular senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615160

21 August 2018

Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide activates NFkappaB and the interleukin-6 promoter through NFkappaB-inducing kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine loops driving senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PML NBs associate with the hMre11 complex and p53 at sites of irradiation induced DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of circulating plasma cytokines in cancer patients with high plasma parathyroid hormone-related protein levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hybridoma growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic TGF beta 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic low-grade systemic inflammation causes DNA damage in the lungs of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23385065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/AGING.100520

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Sitelinks

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