(Q33604490)

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Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 July 2017

Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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alternative mRNA splicing, via spliceosome

1 reference

based on heuristic

inferred from title

object named as

Fernanda Ortis

1

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author name string

Najib Naamane

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Daisy Flamez

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Laurence Ladrière

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Fabrice Moore

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Daniel A Cunha

6

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Maikel L Colli

7

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Thomas Thykjaer

8

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Kasper Thorsen

9

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Torben F Orntoft

10

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Decio L Eizirik

11

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Europe PubMed Central

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28 July 2017

language of work or name

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publication date

23 November 2009

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Europe PubMed Central

PubMed publication ID

28 July 2017

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Europe PubMed Central

PubMed publication ID

28 July 2017

59

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Europe PubMed Central

PubMed publication ID

28 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

358-374

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

28 August 2021

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April 2022 Public Data File from Crossref

copyright status

0 references

Overestimation of alternative splicing caused by variable probe characteristics in exon arrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

The anti-interleukin-1 in type 1 diabetes action trial--background and rationale

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Etanercept treatment in children with new-onset type 1 diabetes: pilot randomized, placebo-controlled, double-blind study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

HIF-1 in the inflammatory microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Beta cell apoptosis in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

The SR protein family of splicing factors: master regulators of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Identification of common genetic variants that account for transcript isoform variation between human populations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Alternative isoform regulation in human tissue transcriptomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

A23187, ionomycin and thapsigargin upregulate mRNA of HIF-1alpha via endoplasmic reticulum stress rather than a rise in intracellular calcium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

The role for endoplasmic reticulum stress in diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

The chemokine network. II. On how polymorphisms and alternative splicing increase the number of molecular species and configure intricate patterns of disease susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

The vicious cycle of apoptotic beta-cell death in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

IRF-7: new role in the regulation of genes involved in adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Alternative splicing: new insights from global analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Is HIF-1alpha a pro- or an anti-apoptotic protein?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Differential splicing of the IA-2 mRNA in pancreas and lymphoid organs as a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

21 June 2018

Intolerant of glucose and gasping for oxygen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

30 October 2018

Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

30 October 2018

Beta cell proliferation and growth factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

30 October 2018

Expression of the citrulline-nitric oxide cycle in rodent and human pancreatic beta-cells: induction of argininosuccinate synthetase by cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809955

30 October 2018

Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/19934004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19934004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-lβ-Induced Nitric Oxide Production in Isolated Rat Pancreatic Islets Requires Gene Transcription and May Lead to Inhibition of the Krebs Cycle Enzyme Aconitase*

1 reference

https://pubmed.ncbi.nlm.nih.gov/19934004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative Splicing of Human Inducible Nitric-Oxide Synthase mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19934004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

1 reference

https://pubmed.ncbi.nlm.nih.gov/19934004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19934004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-Inducible Factor-1 (HIF-1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19934004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophages and dendritic cells infiltrating islets with or without beta cells produce tumour necrosis factor-alpha in patients with recent-onset type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19934004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19934004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19934004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB09-1159

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

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