(Q33753629)

29 July 2017

title

Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks (English)

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29 July 2017

3

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29 July 2017

Oliver Limbo

1

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author name string

Mary E Porter-Goff

series ordinal

2

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29 July 2017

Paul Russell

series ordinal

4

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29 July 2017

language of work or name

English

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publication date

22 November 2010

1 reference

Molecular and Cellular Biology

29 July 2017

published in

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29 July 2017

volume

31

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29 July 2017

issue

3

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29 July 2017

page(s)

573-583

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3028622/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage

21 June 2018

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Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

21 June 2018

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CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

21 June 2018

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Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks

21 June 2018

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The role of MRN in the S-phase DNA damage checkpoint is independent of its Ctp1-dependent roles in double-strand break repair and checkpoint signaling

21 June 2018

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Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

21 June 2018

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Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation

21 June 2018

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Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

21 June 2018

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Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends

21 June 2018

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Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response

21 June 2018

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Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair

21 June 2018

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ATR-dependent pathways control hEXO1 stability in response to stalled forks.

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Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex

21 June 2018

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Human CtIP promotes DNA end resection

21 June 2018

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Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination

21 June 2018

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Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

21 June 2018

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Replication protein A directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions

21 June 2018

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21 June 2018

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21 June 2018

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Rapid activation of ATR by ionizing radiation requires ATM and Mre11

21 June 2018

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

21 June 2018

1 reference

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The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

21 June 2018

1 reference

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Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activity

21 June 2018

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ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1.

21 June 2018

1 reference

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ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

21 June 2018

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage

21 June 2018

1 reference

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Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.

21 June 2018

1 reference

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Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Regulation of checkpoint kinases through dynamic interaction with Crb2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Replication protein A-mediated recruitment and activation of Rad17 complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

The G2-phase DNA-damage checkpoint

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Schizosaccharomyces pombe rad32 protein: a phosphoprotein with an essential phosphoesterase motif required for repair of DNA double strand breaks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Covalent protein-DNA complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

The P. furiosus mre11/rad50 complex promotes 5' strand resection at a DNA double-strand break

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Homo-oligomerization is the essential function of the tandem BRCT domains in the checkpoint protein Crb2.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

Association of Mre11p with double-strand break sites during yeast meiosis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028622

A DNA damage response pathway controlled by Tel1 and the Mre11 complex

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21098122

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.00994-10

1 reference

29 July 2017

1 reference

29 July 2017

1 reference