(Q33771763)

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Regulated nuclear localization of stress-responsive factors: how the nuclear trafficking of protein kinases and transcription factors contributes to cell survival

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scholarly article

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Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

Regulated nuclear localization of stress-responsive factors: how the nuclear trafficking of protein kinases and transcription factors contributes to cell survival (English)

1 reference

Europe PubMed Central

29 July 2017

author name string

Ferrigno P

1

1 reference

Europe PubMed Central

29 July 2017

Silver PA

2

1 reference

Europe PubMed Central

29 July 2017

language of work or name

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publication date

1 November 1999

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

18

1 reference

Europe PubMed Central

29 July 2017

45

1 reference

Europe PubMed Central

29 July 2017

6129-6134

1 reference

Europe PubMed Central

29 July 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203132

0 references

Mechanism of activation and function of protein kinase B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Identification of a nuclear export receptor for tRNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

The role of exportin-t in selective nuclear export of mature tRNAs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Cell cycle oscillation of phosphatase inhibitor-2 in rat fibroblasts coincident with p34cdc2 restriction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nucleocytoplasmic transport: driving and directing transport.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Protein phosphatase type 1 in mammalian cell mitosis: chromosomal localization and involvement in mitotic exit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

CRM1 is an export receptor for leucine-rich nuclear export signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

MEKK1/JNK signaling stabilizes and activates p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Phosphorylation and association with the transcription factor Atf1 regulate localization of Spc1/Sty1 stress-activated kinase in fission yeast.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Active nucleocytoplasmic shuttling required for function and regulation of stress-activated kinase Spc1/StyI in fission yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Transport into and out of the cell nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

A novel class of RanGTP binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nucleocytoplasmic transport

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Insulin-like growth factor-1-mediated neuroprotection against oxidative stress is associated with activation of nuclear factor kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

In or out? Regulating nuclear transport

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Induction of NF-kappaB by the Akt/PKB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT In vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

A GTPase controlling nuclear trafficking: running the right way or walking RANdomly?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Dynamic localization of the nuclear import receptor and its interactions with transport factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Identification of a tRNA-specific nuclear export receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nucleocytoplasmic transport: the soluble phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Two-way trafficking with Ran.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

The tumor suppressor p53 is subject to both nuclear import and export, and both are fast, energy-dependent and lectin-inhibited

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nucleocytoplasmic transport: signals, mechanisms and regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nucleocytoplasmic transport: the last 200 nanometers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Evidence for a role of CRM1 in signal-mediated nuclear protein export

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Phosphorylation of the transcription factor NFATp inhibits its DNA binding activity in cyclosporin A-treated human B and T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Transport routes through the nuclear pore complex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Transcription factors of the NFAT family: regulation and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Kinase activity-dependent nuclear export opposes stress-induced nuclear accumulation and retention of Hog1 mitogen-activated protein kinase in the budding yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Yrb4p, a yeast ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

How proteins enter the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Exportin 1 (Crm1p) is an essential nuclear export factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

A GTPase distinct from Ran is involved in nuclear protein import

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression. Requirement for phosphorylation at the activation lip and signaling downstream of MKK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Differential methylation and altered conformation of cytoplasmic and nuclear forms of protein phosphatase 2A during cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

RanBP1 is crucial for the release of RanGTP from importin β-related nuclear transport factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

21 January 2018

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning of a second form of rac protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of mRNA export in response to stress in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of IκBα Nuclear Import Pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear uptake control of NF-kappa B by MAD-3, an I kappa B protein present in the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203132

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1203132

1 reference

Europe PubMed Central

29 July 2017

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1 reference

Europe PubMed Central

29 July 2017

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