(Q33784656)

29 July 2017

title

Antiretroviral therapy-induced mitochondrial toxicity: potential mechanisms beyond polymerase-γ inhibition (English)

1 reference

29 July 2017

main subject

anti-retroviral agent

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author name string

S Selvaraj

1

1 reference

29 July 2017

M Ghebremichael

2

1 reference

29 July 2017

M Li

3

1 reference

29 July 2017

Y Foli

4

1 reference

29 July 2017

A Langs-Barlow

5

1 reference

29 July 2017

A Ogbuagu

6

1 reference

29 July 2017

L Barakat

7

1 reference

29 July 2017

E Tubridy

8

1 reference

29 July 2017

R Edifor

9

1 reference

29 July 2017

W Lam

10

1 reference

29 July 2017

Y-C Cheng

11

1 reference

29 July 2017

E Paintsil

12

1 reference

29 July 2017

language of work or name

English

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publication date

17 March 2014

1 reference

Clinical Pharmacology & Therapeutics

29 July 2017

published in

1 reference

29 July 2017

volume

96

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29 July 2017

issue

1

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29 July 2017

page(s)

110-120

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Short communication: The relationship between mitochondrial dysfunction and insulin resistance in HIV-infected children receiving antiretroviral therapy.

29 July 2017

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Altered expression of nucleoside transporter genes (SLC28 and SLC29) in adipose tissue from HIV-1-infected patients

4 July 2018

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Review of recent studies on resistance to cytotoxic deoxynucleoside analogues

4 July 2018

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Some HIV antiretrovirals increase oxidative stress and alter chemokine, cytokine or adiponectin production in human adipocytes and macrophages.

4 July 2018

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Uridine supplementation in HIV lipoatrophy: pilot trial on safety and effect on mitochondrial indices

4 July 2018

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Expression of adenosine triphosphate-binding cassette (ABC) drug transporters in peripheral blood cells: relevance for physiology and pharmacotherapy

4 July 2018

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A brief overview of mechanisms of mitochondrial toxicity from NRTIs

4 July 2018

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Cell culture models for the investigation of NRTI-induced mitochondrial toxicity. Relevance for the prediction of clinical toxicity

4 July 2018

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Possible ways nucleoside analogues can affect mitochondrial DNA content and gene expression during HIV therapy

4 July 2018

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4 July 2018

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4 July 2018

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ATP-binding cassette superfamily transporter gene expression in human primary ovarian carcinoma.

4 July 2018

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Increased replication of non-syncytium-inducing HIV type 1 isolates in monocyte-derived macrophages is linked to advanced disease in infected children

4 July 2018

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Long-term exposure to lifelong therapies

4 July 2018

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Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases

4 July 2018

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4 July 2018

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Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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21 January 2018

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21 January 2018

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Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells

21 January 2018

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Distinct mechanisms for mitochondrial DNA loss in T and B lymphocytes from HIV-infected patients exposed to nucleoside reverse-transcriptase inhibitors and those naive to antiretroviral treatment

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Uridine supplementation for the treatment of antiretroviral therapy-associated lipoatrophy: a randomized, double-blind, placebo-controlled trial.

21 January 2018

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Deoxynucleotide pools and DNA synthesis in resting and PHA-stimulated human lymphocytes treated with mutagens

30 October 2018

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12 December 2020

Tissue distribution and disease manifestations of the tRNA(Lys) A-->G(8344) mitochondrial DNA mutation in a case of myoclonus epilepsy and ragged red fibres

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12 December 2020

Differential incorporation of ara-C, gemcitabine, and fludarabine into replicating and repairing DNA in proliferating human leukemia cells

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12 December 2020

Adverse effects of reverse transcriptase inhibitors: mitochondrial toxicity as common pathway

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12 December 2020

Mitochondrial DNA levels of peripheral blood mononuclear cells and subcutaneous adipose tissue from thigh, fat and abdomen of HIV-1 seropositive and negative individuals

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12 December 2020

Tissue-specific associations between mitochondrial DNA levels and current treatment status in HIV-infected individuals

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12 December 2020

Mitochondrial (mt)DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patients

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12 December 2020

Expression of MDR1 in epithelial ovarian cancer and its association with disease progression

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12 December 2020

Identifiers

DOI

10.1038/CLPT.2014.64

1 reference

29 July 2017

1 reference

29 July 2017

1 reference