(Q33802540)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

review article

1 reference

title

Recent Developments Using Small Molecules to Target RAD51: How to Best Modulate RAD51 for Anticancer Therapy? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

author name string

Wei Lv

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Alan P Kozikowski

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Philip P Connell

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

publication date

26 October 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

page(s)

2468-2473

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

Replication fork stability confers chemoresistance in BRCA-deficient cells

26 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Combining carbon ion irradiation and non-homologous end-joining repair inhibitor NU7026 efficiently kills cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

A Small-Molecule Inhibitor of RAD51 Reduces Homologous Recombination and Sensitizes Multiple Myeloma Cells to Doxorubicin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Identification and characterization of human Rad51 inhibitors by screening of an existing drug library

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Targeting the homologous recombination pathway by small molecule modulators

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Real-time solution measurement of RAD51- and RecA-mediated strand assimilation without background annealing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Attenuating homologous recombination stimulates an AID-induced antileukemic effect

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Inhibition of homologous recombination in human cells by targeting RAD51 recombinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Identification of specific inhibitors of human RAD51 recombinase using high-throughput screening

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Crystal structure of an archaeal Rad51 homologue in complex with a metatungstate inhibitor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Use of the Rad51 promoter for targeted anti-cancer therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

RAD54 controls access to the invading 3'-OH end after RAD51-mediated DNA strand invasion in homologous recombination in Saccharomyces cerevisiae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

A chemical compound that stimulates the human homologous recombination protein RAD51

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Halenaquinone and xestoquinone derivatives, inhibitors of Cdc25B phosphatase from a Xestospongia sp.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Gleevec-mediated inhibition of Rad51 expression and enhancement of tumor cell radiosensitivity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Effects of HsRad51 overexpression on cell proliferation, cell cycle progression, and apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Homologous recombinational repair of DNA ensures mammalian chromosome stability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Antisense inhibition of the RAD51 enhances radiosensitivity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Model for Homologous Recombination During Transfer of DNA into Mouse L Cells: Role for DNA Ends in the Recombination Process

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Effects of paraventricular lesions on stimulated ACTH release and CRF in stalk-median eminence of the rat.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Marine sponge polyketide inhibitors of protein tyrosine kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

Regulation of homologous recombination in eukaryotes

28 July 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

The consequences of Rad51 overexpression for normal and tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

Homologous recombinational repair vis-à-vis chlorambucil resistance in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

A small molecule inhibitor of human RAD51 potentiates breast cancer cell killing by therapeutic agents in mouse xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

Halenaquinone, a chemical compound that specifically inhibits the secondary DNA binding of RAD51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

Development of Small Molecules that Specifically Inhibit the D-loop Activity of RAD51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201600426

Elevated levels of Rad51 recombination protein in tumor cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472043

BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27781374

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/CMDC.201600426

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781374%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

PubMed publication ID

27781374

1 reference