(Q33803472)

29 July 2017

title

Circadian clock: linking epigenetics to aging (English)

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29 July 2017

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2

Paolo Sassone-Corsi

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29 July 2017

Ricardo Orozco-Solis

1

1 reference

29 July 2017

publication date

1 June 2014

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Current Opinion in Genetics & Development

29 July 2017

published in

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29 July 2017

volume

26

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29 July 2017

page(s)

66-72

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The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis.

29 July 2017

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BMAL1-dependent regulation of the mTOR signaling pathway delays aging

4 July 2018

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Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging

4 July 2018

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Reprogramming of the circadian clock by nutritional challenge.

4 July 2018

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ROS stress resets circadian clocks to coordinate pro-survival signals

4 July 2018

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mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome

4 July 2018

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Cycles in spatial and temporal chromosomal organization driven by the circadian clock

4 July 2018

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Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice

4 July 2018

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Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH.

4 July 2018

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Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling

4 July 2018

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Regulation of circadian clocks by redox homeostasis

4 July 2018

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SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging

4 July 2018

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Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

4 July 2018

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Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain

4 July 2018

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Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome

4 July 2018

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The circadian epigenome: how metabolism talks to chromatin remodeling

4 July 2018

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SIRT3 reverses aging-associated degeneration

4 July 2018

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Circadian acetylome reveals regulation of mitochondrial metabolic pathways

4 July 2018

1 reference

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Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1

4 July 2018

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mTOR is a key modulator of ageing and age-related disease

4 July 2018

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Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

4 July 2018

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Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption

4 July 2018

1 reference

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Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity

4 July 2018

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The circadian clock and pathology of the ageing brain

4 July 2018

1 reference

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The time of metabolism: NAD+, SIRT1, and the circadian clock

4 July 2018

1 reference

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SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance

4 July 2018

1 reference

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Serum factors in older individuals change cellular clock properties

4 July 2018

1 reference

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Metformin for aging and cancer prevention

4 July 2018

1 reference

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Plasticity and specificity of the circadian epigenome

4 July 2018

1 reference

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SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity

4 July 2018

1 reference

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4 July 2018

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The mammalian circadian timing system: organization and coordination of central and peripheral clocks

4 July 2018

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Hypothalamic Sirt1 regulates food intake in a rodent model system

4 July 2018

1 reference

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Metabolism and cancer: the circadian clock connection

4 July 2018

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AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

SIRT1 regulates circadian clock gene expression through PER2 deacetylation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

CLOCK-mediated acetylation of BMAL1 controls circadian function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Chronobiology in the endocrine system

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Environmental epigenomics and disease susceptibility

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Hypothalamic regulation of sleep and circadian rhythms

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Melatonin, aging, and age-related diseases: perspectives for prevention, intervention, and therapy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Living by the clock: the circadian pacemaker in older people

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Circadian rhythms, oxidative stress, and antioxidative defense mechanisms

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

The "other" circadian system: food as a Zeitgeber

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Rhythmic transcription: the molecular basis of circadian melatonin synthesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

Pineal cross-transplantation (old-to-young and vice versa) as evidence for an endogenous "aging clock".

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

In vivo evidence for a controlled offset of melatonin synthesis at dawn by the suprachiasmatic nucleus in the rat.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

The significance of circadian organization for longevity in the golden hamster

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472345

10.1016/J.GDE.2014.06.003

11 August 2018

Identifiers

DOI

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29 July 2017

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29 July 2017

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