(Q33807844)

29 July 2017

1 reference

title

Maintenance of genomic integrity by p53: complementary roles for activated and non-activated p53. (English)

1 reference

29 July 2017

Albrechtsen N

1

1 reference

29 July 2017

Dornreiter I

2

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29 July 2017

Grosse F

3

1 reference

29 July 2017

Kim E

4

1 reference

29 July 2017

Wiesmüller L

5

1 reference

29 July 2017

Deppert W

6

1 reference

29 July 2017

language of work or name

English

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publication date

1 December 1999

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29 July 2017

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29 July 2017

volume

18

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29 July 2017

issue

53

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29 July 2017

page(s)

7706-7717

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1202952

29 July 2017

exact match

0 references

cites work

Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

The role of specific isoforms of 14-3-3 protein in regulating protein kinase activity in the brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Post-translationally modified 14-3-3 isoforms and inhibition of protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Recruitment of p300/CBP in p53-dependent signal pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

The CBP co-activator is a histone acetyltransferase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Mechanisms of p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Mutator phenotypes in human colorectal carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Genetic steps in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Expression of SV40 large T antigen stimulates reversion of a chromosomal gene duplication in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Tumour suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Female embryonic lethality in mice nullizygous for both Msh2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Evidence for free and metabolically stable p53 protein in nuclear subfractions of simian virus 40-transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Specific mismatch recognition in heteroduplex intermediates by p53 suggests a role in fidelity control of homologous recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Definition of a consensus binding site for p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Enhancement of DNA repair in human skin cells by thymidine dinucleotides: evidence for a p53-mediated mammalian SOS response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Identification of mismatch repair genes and their role in the development of cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Isolation and characterization of DNA sequences that are specifically bound by wild-type p53 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Modulation of DNA Topoisomerase I Activity byp53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53 in growth control and neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

A super new twist on the initiation of meiotic recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53--integrating the complexity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Illegitimate recombination leading to allelic loss and unbalanced translocation in p53-mutated human lymphoblastoid cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Excision of mismatched nucleotides from DNA: a potential mechanism for enhancing DNA replication fidelity by the wild-type p53 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Allosteric activation of latent p53 tetramers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Regulation of the specific DNA binding function of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Small peptides activate the latent sequence-specific DNA binding function of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53-dependent growth arrest of REF52 cells containing newly amplified DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Different regulation of the p53 core domain activities 3'-to-5' exonuclease and sequence-specific DNA binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

High frequency of homologous recombination in mammalian cells between endogenous and introduced SV40 genomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

High mobility group protein-1 (HMG-1) is a unique activator of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Covalent and noncovalent modifiers of the p53 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Homologous recombination of monkey alpha-satellite repeats in an in vitro simian virus 40 replication system: possible association of recombination with DNA replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

DNA-conformation is an important determinant of sequence-specific DNA binding by tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Surface plasmon resonance measurements reveal stable complex formation between p53 and DNA polymerase alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

MDM2--arbiter of p53's destruction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Human p53 binds Holliday junctions strongly and facilitates their cleavage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

The BRCA2 gene product functionally interacts with p53 and RAD51

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Regulation of DNA binding and transactivation in p53 by nuclear localization and phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Inactivation of p53 results in high rates of homologous recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Faulty DNA polymerase delta/epsilon-mediated excision repair in response to gamma radiation or ultraviolet light in p53-deficient fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

DNA mismatch correction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Mismatch repair, genetic stability, and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53 Protein exhibits 3'-to-5' exonuclease activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

DNA polymerases alpha and beta are required for DNA repair in an efficient nuclear extract from Xenopus oocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

The transcriptional coactivators p300 and CBP are histone acetyltransferases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

BRCA1 regulates p53-dependent gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Simian virus 40 large tumor antigen alone or two cooperating oncogenes convert REF52 cells to a state permissive for gene amplification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Carcinogenesis. Missing mismatch repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

DNA damage activates p53 through a phosphorylation-acetylation cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Excision repair of UV-damaged plasmid DNA in Xenopus oocytes is mediated by DNA polymerase alpha (and/or delta)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Regulation of CAK kinase activity by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Role of wild type p53 in the G2 phase: regulation of the gamma-irradiation-induced delay and DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Aphidicolin-induced topological and recombinational events in simian virus 40

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Molecular cloning of the human DNA excision repair gene ERCC-6

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53 function and dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Eukaryotic DNA polymerases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Molecular evolution of the 14-3-3 protein family.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p53 modulation of TFIIH-associated nucleotide excision repair activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Which DNA polymerases are used for DNA-repair in eukaryotes?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Meiotic cells monitor the status of the interhomolog recombination complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202952

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202952

1 reference

Dimensions Publication ID

29 July 2017

1023665084

0 references

1 reference