(Q33809888)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284830%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

First pharmacophore model of CCR3 receptor antagonists and its homology model-assisted, stepwise virtual screening (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284830%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

4

1 reference

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21 January 2020

author name string

Vaibhav Jain

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284830%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Parameswaran Saravanan

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284830%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Akanksha Arvind

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284830%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

publication date

1 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284830%20AND%20SRC:MED&resulttype=core&format=json

Chemical Biology and Drug Design

21 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284830%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

volume

77

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284830%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284830%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

373-387

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21284830%20AND%20SRC:MED&resulttype=core&format=json

Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease

21 January 2020

cites work

1 reference

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The chemokine, eotaxin, activates guinea-pig eosinophils in vitro and causes their accumulation into the lung in vivo

21 January 2018

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Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis

21 January 2018

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Chemokines, leukocytes, and atherosclerosis

21 January 2018

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CCL chemokines and asthma

21 January 2018

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The eosinophil and bronchial asthma: current understanding

21 January 2018

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CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation

21 January 2018

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The N-terminal extracellular segments of the chemokine receptors CCR1 and CCR3 are determinants for MIP-1alpha and eotaxin binding, respectively, but a second domain is essential for efficient receptor activation

21 January 2018

1 reference

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Alanine scanning mutagenesis of the chemokine receptor CCR3 reveals distinct extracellular residues involved in recognition of the eotaxin family of chemokines

21 January 2018

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

21 January 2018

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A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry.

21 January 2018

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In vitro and in vivo characterization of a novel CCR3 antagonist, YM-344031.

21 January 2018

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A novel, selective, and orally available antagonist for CC chemokine receptor 3.

21 January 2018

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Novel ligands for the chemokine receptor-3 (CCR3): a receptor-modeling study based on 5D-QSAR.

21 January 2018

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Small molecule receptor agonists and antagonists of CCR3 provide insight into mechanisms of chemokine receptor activation.

21 January 2018

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Ligand-based molecular design of 4-benzylpiperidinealkylureas and amides as CCR3 antagonists

21 January 2018

1 reference

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The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure

21 January 2018

1 reference

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Comparative protein structure modeling of genes and genomes

21 January 2018

1 reference

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PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

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Verification of protein structures: patterns of nonbonded atomic interactions

21 January 2018

1 reference

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Recognition of errors in three-dimensional structures of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01088.X

A fast SHAKE algorithm to solve distance constraint equations for small molecules in molecular dynamics simulations

21 January 2018

1 reference

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Urea based CCR3 antagonists employing a tetrahydro-1,3-oxazin-2-one spacer

21 January 2018

1 reference

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From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: the discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis

21 January 2018

1 reference

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From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part II: Acyclic replacements for the (3S)-3-benzylpiperidine in a series of potent CCR3 antagonists

21 January 2018

1 reference

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CC chemokine receptor-3 (CCR3) antagonists: improving the selectivity of DPC168 by reducing central ring lipophilicity.

21 January 2018

1 reference

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Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potency.

21 January 2018

1 reference

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N-Arylalkylpiperidine urea derivatives as CC chemokine receptor-3 (CCR3) antagonists

21 January 2018

1 reference

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Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists

21 January 2018

1 reference

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CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure-activity relationships

21 January 2018

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Discovery and structure-activity relationship of N-(ureidoalkyl)-benzyl-piperidines as potent small molecule CC chemokine receptor-3 (CCR3) antagonists.

21 January 2018

1 reference

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Discovery of a novel CCR3 selective antagonist

21 January 2018

1 reference

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Discovery of potent and selective phenylalanine derived CCR3 receptor antagonists. Part 2.

21 January 2018

1 reference

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Structure-activity relationships of 2-(benzothiazolylthio)acetamide class of CCR3 selective antagonist

21 January 2018

1 reference

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Synthesis and structure-activity relationships of N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide derivatives as novel CCR3 antagonists.

21 January 2018

1 reference

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Development and validation of a genetic algorithm for flexible docking

21 January 2018

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Site-directed mutagenesis of CC chemokine receptor 1 reveals the mechanism of action of UCB 35625, a small molecule chemokine receptor antagonist.

21 January 2018

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Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle

21 January 2018

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A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5

21 January 2018

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Chemokines, chemokine receptors and small-molecule antagonists: recent developments

21 January 2018

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Binding of 2-aryl-4-(piperidin-1-yl)butanamines and 1,3,4-trisubstituted pyrrolidines to human CCR5: a molecular modeling-guided mutagenesis study of the binding pocket

21 January 2018

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Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry.

21 January 2018

1 reference

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The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle

21 January 2018

1 reference

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Drug-like properties and the causes of poor solubility and poor permeability

21 January 2018

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Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities

21 January 2018

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Distinct functional sites for human immunodeficiency virus type 1 and stromal cell-derived factor 1alpha on CXCR4 transmembrane helical domains

21 January 2018

1 reference

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