(Q33894600)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

review article

3 references

4 July 2020

22 December 2020

Beyond oxygen: complex regulation and activity of hypoxia inducible factors in pregnancy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

9 references

14 March 2019

19 June 2019

7 October 2019

19 October 2019

4 November 2019

11 December 2019

22 December 2019

4 July 2020

22 December 2020

1 reference

19 October 2019

1 reference

4 November 2019

1 reference

11 December 2019

1 reference

22 December 2019

1 reference

4 July 2020

hypoxia-inducible factor 1

1 reference

22 December 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Amanda Sferruzzi-Perri

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Jeremy G. Thompson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Claire T. Roberts

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

K L Kind

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

1 reference

19 November 2009

10 references

14 March 2019

19 June 2019

7 October 2019

19 October 2019

4 November 2019

11 December 2019

22 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

4 July 2020

22 December 2020

Human Reproduction Update

10 references

14 March 2019

19 June 2019

7 October 2019

19 October 2019

4 November 2019

11 December 2019

22 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

4 July 2020

22 December 2020

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

415-431

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial

12 February 2020

copyright license

9 references

14 March 2019

19 June 2019

7 October 2019

19 October 2019

4 November 2019

11 December 2019

22 December 2019

4 July 2020

22 December 2020

on focus list of Wikimedia project

ScienceSource

0 references

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Hypoxic upregulation of glucose transporters in BeWo choriocarcinoma cells is mediated by hypoxia-inducible factor-1

5 July 2018

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5 July 2018

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Chronic hypoxia in vivo reduces placental oxidative stress

5 July 2018

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5 July 2018

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Effect of low oxygen concentrations on trophoblast-like cell line invasion

5 July 2018

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Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression.

5 July 2018

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Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta

5 July 2018

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5 July 2018

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TNFalpha-mediated induction of PAI-1 restricts invasion of HTR-8/SVneo trophoblast cells

5 July 2018

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Effects of chronic hypoxia in vivo on the expression of human placental glucose transporters

5 July 2018

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Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Induction of glucose transporter 1 expression through hypoxia-inducible factor 1alpha under hypoxic conditions in trophoblast-derived cells

5 July 2018

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Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae

5 July 2018

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5 July 2018

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Natural antisense transcripts of HIF-1alpha are conserved in rodents.

5 July 2018

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What's new in the IGF-binding proteins?

5 July 2018

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Insulin-like growth factor-II regulates the expression of vascular endothelial growth factor by the human keratinocyte cell line HaCaT.

5 July 2018

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Hypoxia-inducible factor-1 transactivates transforming growth factor-beta3 in trophoblast

5 July 2018

1 reference

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Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor

5 July 2018

1 reference

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Maternal adaptation to high-altitude pregnancy: an experiment of nature--a review.

5 July 2018

1 reference

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Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha

5 July 2018

1 reference

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Failure of physiologic transformation of the spiral arteries in patients with preterm labor and intact membranes

5 July 2018

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UTERINE BLOOD FLOW AND PLACENTAL CIRCULATION.

5 July 2018

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The placenta at high altitude

5 July 2018

1 reference

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Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1alpha through a nuclear factor-kappaB-dependent pathway

5 July 2018

1 reference

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Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2

5 July 2018

1 reference

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Noncatalytic domain of uPA stimulates human extravillous trophoblast migration by using phospholipase C, phosphatidylinositol 3-kinase and mitogen-activated protein kinase

5 July 2018

1 reference

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Binding of urokinase-type plasminogen activator receptor (uPAR) to the mannose 6-phosphate/insulin-like growth factor II receptor: contrasting interactions of full-length and soluble forms of uPAR

5 July 2018

1 reference

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HIF hydroxylation and the mammalian oxygen-sensing pathway

5 July 2018

1 reference

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Hypoxia-inducible factor and its biomedical relevance

5 July 2018

1 reference

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Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

5 July 2018

1 reference

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Trophoblastic oxidative stress in relation to temporal and regional differences in maternal placental blood flow in normal and abnormal early pregnancies

5 July 2018

1 reference

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Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1

5 July 2018

1 reference

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IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms

5 July 2018

1 reference

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Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex

5 July 2018

1 reference

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Angiotensin II inhibits human trophoblast invasion through AT1 receptor activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Adriana and Luisa Castellucci Award lecture 2001. Hypoxia inducible factor-1: oxygen regulation of trophoblast differentiation in normal and pre-eclamptic pregnancies--a review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

The regional expression of insulin-like growth factor II (IGF-II) and insulin-like growth factor binding protein-1 (IGFBP-1) in the placentae of women with pre-eclampsia

5 July 2018

1 reference

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Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Transforming growth factor-beta1 inhibits steroidogenesis in human trophoblast cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

The regulation and localization of angiopoietin-1, -2, and their receptor Tie2 in normal and pathologic human placentae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

A conserved family of prolyl-4-hydroxylases that modify HIF

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Stimulation of human extravillous trophoblast migration by IGF-II is mediated by IGF type 2 receptor involving inhibitory G protein(s) and phosphorylation of MAPK.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Onset of maternal arterial blood flow and placental oxidative stress. A possible factor in human early pregnancy failure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Does plasminogen activator inhibitor-1 (PAI-1) control trophoblast invasion? A study of fetal and maternal tissue in intrauterine, tubal and molar pregnancies.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Oxygen and placental development during the first trimester: implications for the pathophysiology of pre-eclampsia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Extracellular matrix composition and hypoxia regulate the expression of HLA-G and integrins in a human trophoblast cell line.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Role of HIF-1 as a transcription factor involved in embryonic development, cancer progression and apoptosis (review).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Maternal arterial connections to the placental intervillous space during the first trimester of human pregnancy: the Boyd collection revisited

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Inhibition of TGF-beta 3 restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Regulated expression of cadherin-11 in human extravillous cytotrophoblasts undergoing aggregation and fusion in response to transforming growth factor beta 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Molecular genetics of implantation in the mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Variations in expression of copper/zinc superoxide dismutase in villous trophoblast of the human placenta with gestational age.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Plasminogen activator inhibitor-1 represses integrin- and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Effect of transforming growth factor-beta on the plasminogen activator system in cultured first trimester human cytotrophoblasts.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

An essential role for p300/CBP in the cellular response to hypoxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

In vivo expression of mRNAs encoding hypoxia-inducible factor 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Transforming growth factor-beta stimulates trophoblast oncofetal fibronectin synthesis in vitro: implications for trophoblast implantation in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Purification and characterization of hypoxia-inducible factor 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Somatomedins in pregnancy: a cross-sectional study of insulin-like growth factors I and II and somatomedin peptide content in normal human pregnancies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Histological study of the materno-embryonic interface in spontaneous abortion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

The human placenta becomes haemochorial at the 13th week of pregnancy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Placental bed biopsies in placental abruption

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Insulin-like growth factor-II and its binding proteins in placental development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Involvement of the plasmin system in dissociation of the insulin-like growth factor-binding protein complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

The effect of vascular origin, oxygen, and tumour necrosis factor alpha on trophoblast invasion of maternal arteries in vitro.

5 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Expression of hypoxia-inducible factors in the peri-implantation mouse uterus is regulated in a cell-specific and ovarian steroid hormone-dependent manner. Evidence for differential function of HIFs during early pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Opposite effects of transforming growth factor-beta activation and rho-associated kinase inhibition on human trophoblast migration in a reconstituted placental-endometrial coculture system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Transforming growth factor-beta stimulates trophoblast oncofetal fibronectin synthesis in vitro: implications for trophoblast implantation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Urokinase type plasminogen activator receptor is involved in insulin-like growth factor-induced migration of rhabdomyosarcoma cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Regulation of human placental development by oxygen tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Human cytotrophoblast expression of the von Hippel-Lindau protein is downregulated during uterine invasion in situ and upregulated by hypoxia in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Hypoxia up-regulates hypoxia-inducible factor-1alpha expression through RhoA activation in trophoblast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Hypoxia rapidly activates HIF-3alpha mRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Non-hypoxic induction of HIF-3alpha by 2-deoxy-D-glucose and insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Regulation of trophoblast invasion by IL-1beta and TGF-beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Elevated Serum Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR-1) Levels in Women with Preeclampsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Uteroplacental ischemia results in proteinuric hypertension and elevated sFLT-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Normoxic induction of the hypoxic-inducible factor-1 alpha by interleukin-1 beta involves the extracellular signal-regulated kinase 1/2 pathway in normal human cytotrophoblast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Inducible expression of endothelial PAS domain protein-1 by hypoxia in human lung adenocarcinoma A549 cells. Role of Src family kinases-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

First-trimester placentation and the risk of antepartum stillbirth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Insulin-like growth factor-II and its binding proteins in placental development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Oxygen regulates human cytotrophoblast differentiation and invasion: implications for endovascular invasion in normal pregnancy and in pre-eclampsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

Placental stress and pre-eclampsia: a revised view.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Complex interactions between hypoxia inducible factors, insulin-like growth factor-II and oxygen in early murine trophoblasts.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Oxygen-regulated Expression of TGF-β3, a Growth Factor Involved in Trophoblast Differentiation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Natural antisense transcripts of hypoxia-inducible factor 1alpha are detected in different normal and tumour human tissues.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Endocrine, paracrine and autocrine regulation of trophoblastic metalloproteinases

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880912

Failure of physiologic transformation of the spiral arteries in the placental bed in preterm premature rupture of membranes

29 October 2018

2 references

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP046

21 January 2018

12 December 2020

Changes in concentration, localization and activity of catalase within the human placenta during early gestation

1 reference

12 December 2020

Hypoxia stimulates urokinase receptor expression through a heme protein-dependent pathway

1 reference

12 December 2020

Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms

1 reference

12 December 2020

Comparison of ultrasonographic and Doppler mapping of the intervillous circulation in normal and abnormal early pregnancies

1 reference

12 December 2020

Impaired oxygen-dependent reduction of HIF-1alpha and -2alpha proteins in pre-eclamptic placentae

1 reference

12 December 2020

Immunohistochemical study of transferrin receptor expression in the placenta of pre-eclamptic pregnancy

1 reference

12 December 2020

Regulation of hypoxia-inducible factor-1alpha by cyclical mechanical stretch in rat vascular smooth muscle cells

1 reference

12 December 2020

Overexpression of the soluble vascular endothelial growth factor receptor in preeclamptic patients: pathophysiological consequences

1 reference

12 December 2020

Tumor necrosis factor-alpha inhibits trophoblast migration through elevation of plasminogen activator inhibitor-1 in first-trimester villous explant cultures

1 reference

12 December 2020

Expression of urokinase receptors by human trophoblast. A histochemical and ultrastructural analysis

1 reference

12 December 2020

Functional role of cell surface integrins on human trophoblast cell migration: regulation by TGF-beta, IGF-II, and IGFBP-1

1 reference

12 December 2020

Comparison of colour Doppler features and pathological findings in complicated early pregnancy

1 reference

12 December 2020

Longitudinal evaluation of uteroplacental and umbilical blood flow changes in normal early pregnancy

1 reference

12 December 2020

Purification and characterization of the insulin-like growth factor-binding protein-1 phosphoform found in normal plasma

1 reference

12 December 2020

The effect of hypoxia on human trophoblast in culture: morphology, glucose transport and metabolism

1 reference

12 December 2020

Role of insulin-like growth factor binding proteins in controlling IGF actions

1 reference

12 December 2020

Autocrine-paracrine regulation of human trophoblast invasiveness by insulin-like growth factor (IGF)-II and IGF-binding protein (IGFBP)-1

1 reference

12 December 2020

A Vascular Endothelial Growth Factor Antagonist Is Produced by the Human Placenta and Released into the Maternal Circulation1

1 reference

12 December 2020

Stimulation of plasminogen activator inhibitor-1 expression in immortalized human trophoblast cells cultured under low levels of oxygen

1 reference

12 December 2020

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

1 reference

12 December 2020

M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1

1 reference

12 December 2020

Effects of tumour necrosis factor-alpha, interleukin-1 alpha, macrophage colony stimulating factor and transforming growth factor beta on trophoblastic matrix metalloproteinases

1 reference

12 December 2020

Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation

1 reference

12 December 2020

Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1

1 reference

12 December 2020

Regulation of human villous trophoblast by insulin-like growth factors and insulin-like growth factor-binding protein-1

1 reference

12 December 2020

Low oxygen concentrations inhibit trophoblast cell invasion from early gestation placental explants via alterations in levels of the urokinase plasminogen activator system

1 reference

12 December 2020

Dynamic HIF1A Regulation During Human Placental Development1

1 reference

12 December 2020

The effects of oxygen concentration and gestational age on extravillous trophoblast outgrowth in a human first trimester villous explant model

1 reference

12 December 2020

Induction of vascular endothelial growth factor by IGF-I in osteoblast-like cells is mediated by the PI3K signaling pathway through the hypoxia-inducible factor-2alpha

1 reference

12 December 2020

Placental HIF-1 alpha, HIF-2 alpha, membrane and soluble VEGF receptor-1 proteins are not increased in normotensive pregnancies complicated by late-onset intrauterine growth restriction

1 reference

12 December 2020

Differential gene expression of somatotrophic and growth factors in response to in vivo hypoxia in human placenta

1 reference

12 December 2020

Angiotensin II mimics the hypoxic effect on regulating trophoblast proliferation and differentiation in human placental explant cultures

1 reference

12 December 2020

Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta

1 reference

12 December 2020

Placental vascular morphogenesis

1 reference

12 December 2020

Selective overexpression of the hypoxia-inducible transcription factor, HIF-2alpha, in placentas from women with preeclampsia

1 reference

12 December 2020

Evaluation of respiratory gases and acid-base gradients in human fetal fluids and uteroplacental tissue between 7 and 16 weeks' gestation

1 reference

12 December 2020

Hypoxia: Implications for Implantation to Delivery—A Workshop Report

1 reference

12 December 2020

Inadequate maternal vascular response to placentation in pregnancies complicated by pre-eclampsia and by small-for-gestational age infants

1 reference

12 December 2020

Echographic [corrected] and anatomic studies of the maternotrophoblastic border during the first trimester of pregnancy

1 reference

12 December 2020

Defective haemochorial placentation as a cause of miscarriage: a preliminary study

1 reference

12 December 2020

Circulating levels of insulin-like growth factors increase and molecular forms of their serum binding proteins change with human pregnancy

1 reference

12 December 2020

Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy

1 reference

12 December 2020

Identifiers

DOI

10.1093/HUMUPD/DMP046

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926662%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference