(Q33898945)

29 July 2017

title

Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis (English)

1 reference

non-alcoholic steatohepatitis

29 July 2017

0 references

1 reference

Caroline C Duwaerts

1

1 reference

29 July 2017

Jacquelyn J Maher

series ordinal

2

1 reference

29 July 2017

publication date

1 June 2014

1 reference

Current hepatology reports

29 July 2017

published in

1 reference

29 July 2017

volume

13

1 reference

29 July 2017

issue

2

1 reference

29 July 2017

page(s)

119-129

1 reference

Systematic review with meta-analysis: non-alcoholic steatohepatitis - a case for personalised treatment based on pathogenic targets

29 July 2017

cites work

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5 July 2018

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Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase

5 July 2018

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Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease

5 July 2018

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Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

5 July 2018

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Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis

5 July 2018

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Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation

5 July 2018

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5 July 2018

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5 July 2018

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Expression and characterization of a PNPLA3 protein isoform (I148M) associated with nonalcoholic fatty liver disease

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease

5 July 2018

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5 July 2018

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Probiotics as an emerging therapeutic strategy to treat NAFLD: focus on molecular and biochemical mechanisms.

5 July 2018

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A dual sugar challenge test for lipogenic sensitivity to dietary fructose

5 July 2018

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Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice

5 July 2018

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Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis

5 July 2018

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Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice

5 July 2018

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Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease

5 July 2018

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Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis

5 July 2018

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Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

5 July 2018

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High-fat diet determines the composition of the murine gut microbiome independently of obesity

5 July 2018

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JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis

5 July 2018

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Correlates and heritability of nonalcoholic fatty liver disease in a minority cohort

5 July 2018

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Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-kappaB-dependent pathways

5 July 2018

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Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance

5 July 2018

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Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

5 July 2018

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GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice

5 July 2018

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Heritability of nonalcoholic fatty liver disease

5 July 2018

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Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction

5 July 2018

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5 July 2018

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A core gut microbiome in obese and lean twins

5 July 2018

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Adipocyte metabolism and obesity

5 July 2018

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Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes

5 July 2018

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Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.

5 July 2018

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Dietary sugars stimulate fatty acid synthesis in adults

5 July 2018

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Fructose consumption as a risk factor for non-alcoholic fatty liver disease

5 July 2018

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Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice

5 July 2018

1 reference

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TLR4 enhances TGF-beta signaling and hepatic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Obesity-associated improvements in metabolic profile through expansion of adipose tissue

5 July 2018

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Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis

5 July 2018

1 reference

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Metabolic endotoxemia initiates obesity and insulin resistance

5 July 2018

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Mechanisms underlying the resistance to diet-induced obesity in germ-free mice

5 July 2018

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Microbial ecology: human gut microbes associated with obesity

5 July 2018

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Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

5 July 2018

1 reference

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Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

5 July 2018

1 reference

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Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it.

5 July 2018

1 reference

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Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4.

5 July 2018

1 reference

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Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice

5 July 2018

1 reference

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Obesity alters gut microbial ecology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

The roles of leptin and adiponectin: a novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Diversity of the human intestinal microbial flora

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

The gut microbiota as an environmental factor that regulates fat storage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Mitochondrial adaptations to obesity-related oxidant stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Regulation of gene expression by dietary fat.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

The effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects

5 July 2018

1 reference

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Tumor necrosis factor-alpha in sera of obese patients: fall with weight loss

5 July 2018

1 reference

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Steatohepatitis: a tale of two "hits"?

5 July 2018

1 reference

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Contributions of different fatty acid sources to very low-density lipoprotein-triacylglycerol in the fasted and fed states

5 July 2018

1 reference

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Effects of fructose and glucose overfeeding on hepatic insulin sensitivity and intrahepatic lipids in healthy humans.

21 January 2018

1 reference

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Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP.

21 January 2018

1 reference

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JNK1 but not JNK2 promotes the development of steatohepatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

A lipidomic analysis of nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Fatty acid metabolism in the liver, measured by positron emission tomography, is increased in obese individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Increased hepatic de novo lipogenesis and mitochondrial efficiency in a model of obesity induced by diets rich in fructose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

A new model for nonalcoholic steatohepatitis in the rat utilizing total enteral nutrition to overfeed a high-polyunsaturated fat diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Contribution of TIR domain-containing adapter inducing IFN-beta-mediated IL-18 release to LPS-induced liver injury in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Type I Interferons Protect From Toll-Like Receptor 9–Associated Liver Injury and Regulate IL-1 Receptor Antagonist in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Bias in macrophage activation pattern influences non-alcoholic steatohepatitis (NASH) in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Intestinal microbiota in patients with nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11901-014-0224-8

Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Serum levels of tumor necrosis factor-alpha are increased in obese patients with noninsulin-dependent diabetes mellitus.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097318

Variant adiponutrin (PNPLA3) represents a common fibrosis risk gene: non-invasive elastography-based study in chronic liver disease

29 October 2018

1 reference

12 December 2020

Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet

1 reference

12 December 2020

Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis

1 reference

12 December 2020

Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice

1 reference

12 December 2020

Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis

1 reference

12 December 2020

Increased gastrointestinal ethanol production in obese mice: implications for fatty liver disease pathogenesis

1 reference

12 December 2020

Nutrition, intestinal permeability, and blood ethanol levels are altered in patients with nonalcoholic fatty liver disease (NAFLD)

1 reference

12 December 2020

TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-1c (SREBP-1c)

1 reference

12 December 2020

10.1007/S11901-014-0224-8

Identifiers

DOI

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference