(Q33914338)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

title

Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

1 reference

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

8

Marc Peschanski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1

Anne-Laure Egesipe

1 reference

25 March 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

2

Sophie Blondel

1 reference

25 March 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

4

Anne-Laure Jaskowiak

1 reference

25 March 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

Alessandra Lo Cicero

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Claire Navarro

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Annachiara De Sandre-Giovannoli

series ordinal

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Nicolas Levy

series ordinal

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

publication date

10 November 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

NPJ aging and mechanisms of disease

25 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

page(s)

16026

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

25 March 2020

copyright license

start time

10 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5515002/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Modulation of LMNA splicing as a strategy to treat prelamin A diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Enhanced SRSF5 Protein Expression Reinforces Lamin A mRNA Production in HeLa Cells and Fibroblasts of Progeria Patients.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Pluripotent stem cells to model Hutchinson-Gilford progeria syndrome (HGPS): Current trends and future perspectives for drug discovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

A high-content imaging-based screening pipeline for the systematic identification of anti-progeroid compounds.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Antisense oligonucleotide induction of progerin in human myogenic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Induced pluripotent stem cells reveal functional differences between drugs currently investigated in patients with hutchinson-gilford progeria syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Distinct perturbation of the translatome by the antidiabetic drug metformin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Metformin use and mortality among patients with diabetes and atherothrombosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Increased expression of the Hutchinson-Gilford progeria syndrome truncated lamin A transcript during cell aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Phenotype and course of Hutchinson-Gilford progeria syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Trends in acute myocardial infarction in 4 US states between 1992 and 2001: clinical characteristics, quality of care, and outcomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Lamin A-dependent nuclear defects in human aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Lamin a truncation in Hutchinson-Gilford progeria.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5515002

A conserved splicing mechanism of the LMNA gene controls premature aging.

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPJAMD.2016.26

Metformin decelerates aging and development of mammary tumors in HER-2/neu transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPJAMD.2016.26

Metformin slows down aging and extends life span of female SHR mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPJAMD.2016.26

Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPJAMD.2016.26

Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPJAMD.2016.26

Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPJAMD.2016.26

inferred from DOI database lookup

7 January 2021

based on heuristic

Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls

1 reference

https://api.crossref.org/works/10.1038%2FNPJAMD.2016.26

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NPJAMD.2016.26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

25 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28721276%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

PubMed publication ID

28721276

1 reference