(Q33916789)

30 July 2017

title

Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer (English)

1 reference

30 July 2017

8

Swaminathan Sethu

1 reference

30 July 2017

Samah El Ghamrasni

1

1 reference

30 July 2017

Ashwin Pamidi

2

1 reference

30 July 2017

Marie Jo Halaby

3

1 reference

30 July 2017

Miyuki Bohgaki

4

1 reference

30 July 2017

Renato Cardoso

5

1 reference

30 July 2017

Li Li

6

1 reference

30 July 2017

Shriram Venkatesan

7

1 reference

30 July 2017

Atsushi Hirao

9

1 reference

30 July 2017

Tak W Mak

10

1 reference

30 July 2017

Manoor Prakash Hande

11

1 reference

30 July 2017

Anne Hakem

12

1 reference

30 July 2017

Razqallah Hakem

13

1 reference

30 July 2017

publication date

19 May 2011

1 reference

30 July 2017

1 reference

30 July 2017

volume

7

1 reference

30 July 2017

issue

5

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30 July 2017

page(s)

e1001385

1 reference

Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

19 May 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

p53--a Jack of all trades but master of none

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Cellular senescence: hot or what?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Death through a tragedy: mitotic catastrophe

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

DNA-damage repair; the good, the bad, and the ugly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

CHK2 kinase: cancer susceptibility and cancer therapy - two sides of the same coin?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Cellular responses to DNA damage: one signal, multiple choices

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Collaboration of Brca1 and Chk2 in tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Suppression of survivin expression inhibits in vivo tumorigenicity and angiogenesis in gastric cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Cancer predisposition and hematopoietic failure in Rad50(S/S) mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Perturbations of vascular homeostasis and aortic valve abnormalities in fibulin-4 deficient mice.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001385

Involvement of mammalian Mus81 in genome integrity and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001385

Decreased expression of methyl methansulfonate and ultraviolet-sensitive gene clone 81 (Mus81) is correlated with a poor prognosis in patients with hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001385

The impact of a negligent G2/M checkpoint on genomic instability and cancer induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001385

Survivin, cancer networks and pathway-directed drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001385

The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001385

Complex chromosome aberrations persist in individuals many years after occupational exposure to densely ionizing radiation: an mFISH study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001385

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3098187

Functional Interplay of p53 and Mus81 in DNA Damage Responses and Cancer

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21625617

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1001385

1 reference

30 July 2017

1 reference

30 July 2017

1 reference