(Q33926389)

30 July 2017

title

A phosphoramidate substrate analog is a competitive inhibitor of the Tetrahymena group I ribozyme (English)

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30 July 2017

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3

Doudna JA

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30 July 2017

Hanna RL

1

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30 July 2017

Gryaznov SM

series ordinal

2

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30 July 2017

publication date

1 November 2000

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30 July 2017

number of pages

10

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inferred from page(s)

published in

Chemistry and Biology

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30 July 2017

volume

7

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30 July 2017

issue

11

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30 July 2017

page(s)

845-854

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Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis

30 July 2017

cites work

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A comparative database of group I intron structures

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In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence

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7 January 2021

Emerging themes in RNA folding

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The chemistry of self-splicing RNA and RNA enzymes

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7 January 2021

Stereochemical course of catalysis by the Tetrahymena ribozyme

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7 January 2021

The intervening sequence RNA of Tetrahymena is an enzyme

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7 January 2021

Metal ion catalysis in the Tetrahymena ribozyme reaction

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7 January 2021

A second catalytic metal ion in group I ribozyme

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7 January 2021

Three metal ions at the active site of the Tetrahymena group I ribozyme

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7 January 2021

Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes

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7 January 2021

Ribozyme recognition of RNA by tertiary interactions with specific ribose 2′-OH groups

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7 January 2021

DNA cleavage catalysed by the ribozyme from Tetrahymena

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7 January 2021

Quantitating tertiary binding energies of 2' OH groups on the P1 duplex of the Tetrahymena ribozyme: intrinsic binding energy in an RNA enzyme

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7 January 2021

Guanosine binding to the Tetrahymena ribozyme: thermodynamic coupling with oligonucleotide binding

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7 January 2021

Crystal structure of a group I ribozyme domain: principles of RNA packing

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7 January 2021

A preorganized active site in the crystal structure of the Tetrahymena ribozyme

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7 January 2021

The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction

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7 January 2021

Antileukemia effect of c-myc N3'-->P5' phosphoramidate antisense oligonucleotides in vivo

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7 January 2021

Modified (PNA, 2'-O-methyl and phosphoramidate) anti-TAR antisense oligonucleotides as strong and specific inhibitors of in vitro HIV-1 reverse transcription

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7 January 2021

RNase H-independent antisense activity of oligonucleotide N3 '--> P5 ' phosphoramidates.

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7 January 2021

Inhibition of IL-6 in mice by anti-NF-kappaB oligodeoxyribonucleotide N3'-->oligodeoxyribonnucleotide N3' --> P5' phosphoramidates

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7 January 2021

RNA mimetics: oligoribonucleotide N3'-->P5' phosphoramidates

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7 January 2021

Zwitterionic oligodeoxyribonucleotide N3'-->P5' phosphoramidates: synthesis and properties

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7 January 2021

Synthesis of oligodeoxyribonucleotide N3'-->P5' phosphoramidates

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7 January 2021

NMR solution structure of the N3' --> P5' phosphoramidate duplex d(CGCGAATTCGCG)2 by the iterative relaxation matrix approach

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7 January 2021

Stable triple helices formed by oligonucleotide N3'-->P5' phosphoramidates inhibit transcription elongation

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7 January 2021

Oligonucleotide N3'-->P5' phosphoramidates as antisense agents

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7 January 2021

Structural RNA mimetics: N3'-->P5' phosphoramidate DNA analogs of HIV-1 RRE and TAR RNA form A-type helices that bind specifically to Rev and Tat-related peptides

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7 January 2021

Antisense binding enhanced by tertiary interactions: binding of phosphorothioate and N3'-->P5' phosphoramidate hexanucleotides to the catalytic core of a group I ribozyme from the mammalian pathogen Pneumocystis carinii

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7 January 2021

In vitro suicide inhibition of self-splicing of a group I intron from Pneumocystis carinii by an N3' --> P5' phosphoramidate hexanucleotide

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7 January 2021

Synthesis and properties of RNA analogs-oligoribonucleotide N3'-->P5' phosphoramidates

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7 January 2021

Staphylococcal nuclease: Proposed mechanism of action based on structure of enzyme—thymidine 3′,5′-bisphosphate—calcium ion complex at 1.5-Å resolution

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7 January 2021

Optimizing the substrate specificity of a group I intron ribozyme

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7 January 2021

Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site

1 reference

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7 January 2021

Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozyme

1 reference

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7 January 2021

The P5abc peripheral element facilitates preorganization of the tetrahymena group I ribozyme for catalysis

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7 January 2021

Isolation of a local tertiary folding transition in the context of a globally folded RNA.

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7 January 2021

Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting

1 reference

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7 January 2021

Chemical synthesis of biologically active oligoribonucleotides using beta-cyanoethyl protected ribonucleoside phosphoramidites

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7 January 2021

A hydrogen-bonding triad stabilizes the chemical transition state of a group I ribozyme

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7 January 2021

10.1016/S1074-5521(00)00033-8

Identifiers

DOI

1 reference

30 July 2017

1 reference