(Q33934010)

30 July 2017

title

Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma (English)

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30 July 2017

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14

Michael Andreeff

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30 July 2017

7

Sattva S Neelapu

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30 July 2017

8

Larry W Kwak

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30 July 2017

Mariko Yoshimura

1

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30 July 2017

Jo Ishizawa

2

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30 July 2017

Vivian Ruvolo

3

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30 July 2017

Archana Dilip

4

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30 July 2017

Alfonso Quintás-Cardama

5

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30 July 2017

Timothy J McDonnell

6

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30 July 2017

Sharon Shacham

9

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30 July 2017

Michael Kauffman

10

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30 July 2017

Yoko Tabe

11

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30 July 2017

Masako Yokoo

12

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30 July 2017

Shinya Kimura

13

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30 July 2017

Kensuke Kojima

15

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30 July 2017

publication date

3 June 2014

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30 July 2017

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30 July 2017

volume

105

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30 July 2017

issue

7

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30 July 2017

page(s)

795-801

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Novel treatment for mantle cell lymphoma including therapy-resistant tumor by NF-κB and mTOR dual-targeting approach.

30 July 2017

cites work

1 reference

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CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications.

28 July 2018

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Prognostic impact and targeting of CRM1 in acute myeloid leukemia

28 July 2018

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Selective inhibitors of nuclear export for the treatment of non-Hodgkin's lymphomas

28 July 2018

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Selective inhibitors of nuclear export block pancreatic cancer cell proliferation and reduce tumor growth in mice

28 July 2018

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Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia

28 July 2018

1 reference

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Novel selective inhibitors of nuclear export CRM1 antagonists for therapy in mantle cell lymphoma

28 July 2018

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Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells

28 July 2018

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NESdb: a database of NES-containing CRM1 cargoes

28 July 2018

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Nuclear export of proteins and drug resistance in cancer

28 July 2018

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Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells.

28 July 2018

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The nucleolus directly regulates p53 export and degradation

28 July 2018

1 reference

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Decreased sensitivity of 17p-deleted chronic lymphocytic leukemia cells to a small molecule BCL-2 antagonist ABT-737

28 July 2018

1 reference

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Acquisition of p53 mutations in response to the non-genotoxic p53 activator Nutlin-3.

28 July 2018

1 reference

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Transcriptional regulation by p53.

28 July 2018

1 reference

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Cytoplasmic functions of the tumour suppressor p53.

28 July 2018

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The expression of CRM1 is associated with prognosis in human osteosarcoma

28 July 2018

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Advances in the understanding of mantle cell lymphoma

28 July 2018

1 reference

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Expression of the nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 is a prognostic factor in human ovarian cancer

28 July 2018

1 reference

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Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

28 July 2018

1 reference

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A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.

28 July 2018

1 reference

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Small molecule inhibition of HDM2 leads to p53-mediated cell death in retinoblastoma cells

28 July 2018

1 reference

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Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106990

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106990

The importance of p53 location: nuclear or cytoplasmic zip code?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106990

Nuclear transport and cancer: from mechanism to intervention

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106990

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106990

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106990

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106990

Expression of CRM1 in human gliomas and its significance in p27 expression and clinical prognosis.

28 July 2018

1 reference

The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.

21 January 2018

1 reference

Mutation and genomic deletion status of ataxia telangiectasia mutated (ATM) and p53 confer specific gene expression profiles in mantle cell lymphoma

21 January 2018

1 reference

Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome

21 January 2018

1 reference

Systematic identification of genomic markers of drug sensitivity in cancer cells

21 January 2018

1 reference

The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells

21 January 2018

1 reference

Impact of TP53 mutation and 17p deletion in mantle cell lymphoma

21 January 2018

1 reference

CDK4andMDM2Gene Alterations Mainly Occur in Highly Proliferative and Aggressive Mantle Cell Lymphomas with Wild-typeINK4a/ARFLocus

21 January 2018

1 reference

Immunohistochemical evaluation of MYC expression in mantle cell lymphoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106990

29 October 2018

Identifiers

DOI

10.1111/CAS.12430

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30 July 2017

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30 July 2017

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