(Q33944889)

30 July 2017

title

Subcellular distribution of epothilones in human tumor cells (English)

1 reference

30 July 2017

R B Lichtner

1

1 reference

30 July 2017

A Rotgeri

2

1 reference

30 July 2017

T Bunte

3

1 reference

30 July 2017

B Buchmann

4

1 reference

30 July 2017

J Hoffmann

5

1 reference

30 July 2017

W Schwede

6

1 reference

30 July 2017

W Skuballa

7

1 reference

30 July 2017

U Klar

8

1 reference

30 July 2017

language of work or name

English

0 references

publication date

18 September 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

98

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30 July 2017

issue

20

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30 July 2017

page(s)

11743-11748

1 reference

The microtubule-stabilizing agents epothilones A and B and their desoxy-derivatives induce mitotic arrest and apoptosis in human prostate cancer cells.

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Epothilones and related structures--a new class of microtubule inhibitors with potent in vivo antitumor activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Structure of the alpha beta tubulin dimer by electron crystallography

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Synthesis of epothilones A and B in solid and solution phase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Examination by laser scanning confocal fluorescence imaging microscopy of the subcellular localisation of anthracyclines in parent and multidrug resistant cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Taxol: mechanisms of action and resistance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Removal of beta III isotype enhances taxol induced microtubule assembly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Structure and utilization of tubulin isotypes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug-resistant cell lines using laser-assisted confocal microscopy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Kinetics of colchicine binding to purified beta-tubulin isotypes from bovine brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58800

Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Total Synthesis of(–)-Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Development and characterisation of novel human multidrug resistant mammary carcinoma lines in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

New synthetic inhibitors of microtubule depolymerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Beta-tubulin isotypes purified from bovine brain have different relative stabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified beta-tubulin isotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Total Synthesis of(–)-Epothilone A

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Total Synthesis of(−)-Epothilone A

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Total Synthesis of Epothilone A: The Olefin Metathesis Approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

On the total synthesis and preliminary biological evaluations of 15(R) and 15(S) aza-dEpoB: a Mitsunobu inversion at C15 in pre-epothilone fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Characterization of the Taxol Binding Site on the Microtubule

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Immunocytochemical localization of cytoskeletal proteins and histone 2B in isolated membrane-depleted nuclei, metaphase chromatin, and whole Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Presence of the betaII isotype of tubulin in the nuclei of cultured mesangial cells from rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.171023398

Quantification of cells cultured on 96-well plates

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11562452

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.171023398

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference