(Q33959452)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Cleavage of the sarcin-ricin loop of 23S rRNA differentially affects EF-G and EF-Tu binding (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

José G Gavilanes

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Alvaro Martínez-del-Pozo

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

2

Elisa Alvarez-García

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Simpson Joseph

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

9 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

published in

Nucleic Acids Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

4108-4119

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 2.5 Generic

19 January 2020

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2896532/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA

5 July 2018

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The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

5 July 2018

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GTPase activation of elongation factor EF-Tu by the ribosome during decoding

5 July 2018

1 reference

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The identification of the determinants of the cyclic, sequential binding of elongation factors tu and g to the ribosome

5 July 2018

1 reference

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Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

5 July 2018

1 reference

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Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin

5 July 2018

1 reference

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The process of mRNA-tRNA translocation

5 July 2018

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Thiostrepton inhibition of tRNA delivery to the ribosome

5 July 2018

1 reference

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Linkage between substrate recognition and catalysis during cleavage of sarcin/ricin loop RNA by restrictocin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Elongation factor G stabilizes the hybrid-state conformation of the 70S ribosome

5 July 2018

1 reference

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Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation

5 July 2018

1 reference

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Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Kinetically competent intermediates in the translocation step of protein synthesis

5 July 2018

1 reference

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Fungal ribotoxins: molecular dissection of a family of natural killers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The electrostatic character of the ribosomal surface enables extraordinarily rapid target location by ribotoxins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The hybrid state of tRNA binding is an authentic translation elongation intermediate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Ribose 2'-hydroxyl groups in the 5' strand of the acceptor arm of P-site tRNA are not essential for EF-G catalyzed translocation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

How can elongation factors EF-G and EF-Tu discriminate the functional state of the ribosome using the same binding site?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Mechanisms of elongation on the ribosome: dynamics of a macromolecular machine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The common and the distinctive features of the bulged-G motif based on a 1.04 A resolution RNA structure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Locking and unlocking of ribosomal motions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Crystal structures of restrictocin-inhibitor complexes with implications for RNA recognition and base flipping

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Identification of molecular interactions between P-site tRNA and the ribosome essential for translocation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

A ratchet-like inter-subunit reorganization of the ribosome during translocation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The highly refined solution structure of the cytotoxic ribonuclease alpha-sarcin reveals the structural requirements for substrate recognition and ribonucleolytic activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The phenotype of mutations of the base-pair C2658.G2663 that closes the tetraloop in the sarcin/ricin domain of Escherichia coli 23 S ribosomal RNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Large-scale movement of elongation factor G and extensive conformational change of the ribosome during translocation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The two faces of the Escherichia coli 23 S rRNA sarcin/ricin domain: the structure at 1.11 A resolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Thiostrepton inhibits the turnover but not the GTPase of elongation factor G on the ribosome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Induced fit in initial selection and proofreading of aminoacyl-tRNA on the ribosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The phenotype of mutations of G2655 in the sarcin/ricin domain of 23 S ribosomal RNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

EF-G-catalyzed translocation of anticodon stem-loop analogs of transfer RNA in the ribosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The site of action of alpha-sarcin on eukaryotic ribosomes. The sequence at the alpha-sarcin cleavage site in 28 S ribosomal ribonucleic acid.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The ribonuclease activity of the cytotoxin alpha-sarcin. The characteristics of the enzymatic activity of alpha-sarcin with ribosomes and ribonucleic acids as substrates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Evidence that the G2661 region of 23S rRNA is located at the ribosomal binding sites of both elongation factors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Effect of alpha-sarcin and ribosome-inactivating proteins on the interaction of elongation factors with ribosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

A functional pseudoknot in 16S ribosomal RNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The two main states of the elongating ribosome and the role of the α-sarcin stem-loop structure of 23S RNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Effects of some proteins that inactivate the eukaryotic ribosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Specific cleavage of ribosomal RNA caused by alpha sarcin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The sarcin-ricin loop of 23S rRNA is essential for assembly of the functional core of the 50S ribosomal subunit

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

The integrity of the sarcin/ricin domain of 23 S ribosomal RNA is not required for elongation factor-independent peptide synthesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Functional interactions between the G' subdomain of bacterial translation factor EF-G and ribosomal protein L7/L12.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

A conserved base-pair between tRNA and 23 S rRNA in the peptidyl transferase center is important for peptide release.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

EF-G-dependent GTPase on the ribosome. conformational change and fusidic acid inhibition.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

tRNA selection and kinetic proofreading in translation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Interactions of translational factor EF-G with the bacterial ribosome before and after mRNA translocation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Essential role of histidine 84 in elongation factor Tu for the chemical step of GTP hydrolysis on the ribosome

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Catalysis of ribosomal translocation by sparsomycin

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Coupling of GTP hydrolysis by elongation factor G to translocation and factor recycling on the ribosome

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Initiation factor IF2, thiostrepton and micrococcin prevent the binding of elongation factor G to the Escherichia coli ribosome

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896532

Affinity Purification of Ribosomes with a Lethal G2655C Mutation in 23 S rRNA That Affects the Translocation

29 October 2018

1 reference

12 December 2020

Mg2+/NH4+/polyamine system for polyuridine-dependent polyphenylalanine synthesis with near in vivo characteristics

1 reference

12 December 2020

Determination of the 28 S ribosomal RNA identity element (G4319) for alpha-sarcin and the relationship of recognition to the selection of the catalytic site

1 reference

12 December 2020

An A to U transversion at position 1067 of 23 S rRNA from Escherichia coli impairs EF-Tu and EF-G function 1 1Edited by D. E. Draper

1 reference

12 December 2020

Modeling the highly specific ribotoxin recognition of ribosomes

1 reference

12 December 2020

Effects of the active aldehyde group generated by RNA N-glycosidase in the sarcin/ricin domain of rat 28S ribosomal RNA on peptide elongation

1 reference

12 December 2020

RNase U2 and alpha-sarcin: a study of relationships

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKQ151

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215430%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

20215430

1 reference