(Q33993746)

30 July 2017

Designed divergent evolution of enzyme function (English)

1 reference

30 July 2017

0 references

Thomas E Ferrin

2

0 references

Jay Keasling

series ordinal

3

object named as

Jay D Keasling

1 reference

30 July 2017

Yasuo Yoshikuni

1

1 reference

PubMed ID

16495946

30 July 2017

language of work or name

English

0 references

publication date

22 February 2006

1 reference

30 July 2017

1 reference

30 July 2017

440

1 reference

30 July 2017

1078-1082

1 reference

30 July 2017

7087

1 reference

https://scigraph.springernature.com/pub.10.1038/nature04607

30 July 2017

0 references

cites work

Enzyme recruitment in evolution of new function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Catalytic promiscuity and the evolution of new enzymatic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Enzymes with extra talents: moonlighting functions and catalytic promiscuity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Divergent evolution in the enolase superfamily: the interplay of mechanism and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Structural plasticity broadens the specificity of an engineered protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Inversion of stereospecificity of vanillyl-alcohol oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

In vitro evolution of beta-glucuronidase into a beta-galactosidase proceeds through non-specific intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of delta-selinene synthase and gamma-humulene synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases delta-selinene synthase and gamma-humulene synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Crystal structure determination of aristolochene synthase from the blue cheese mold, Penicillium roqueforti

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Functional characterization of nine Norway Spruce TPS genes and evolution of gymnosperm terpene synthases of the TPS-d subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Plant terpenoid synthases: molecular biology and phylogenetic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

An evolutionary trace method defines binding surfaces common to protein families

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Rapid evolution of a protein in vitro by DNA shuffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Comparative protein modeling by satisfaction of spatial restraints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Protein structure prediction and structural genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

X-ray crystal structures of D100E trichodiene synthase and its pyrophosphate complex reveal the basis for terpene product diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Inverse thinking about double mutants of enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Antibody multispecificity mediated by conformational diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

Conformational diversity and protein evolution--a 60-year-old hypothesis revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

inferred from DOI database lookup

7 January 2021

based on heuristic

The 'evolvability' of promiscuous protein functions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

inferred from DOI database lookup

7 January 2021

based on heuristic

Genomic analysis of the terpenoid synthase ( AtTPS) gene family of Arabidopsis thaliana

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04607

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE04607

1 reference

PubMed ID

16495946

Dimensions Publication ID

30 July 2017

0 references

1 reference

PubMed ID

16495946