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Targeting DNA repair pathways for cancer treatment: what's new?
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Europe PubMed Central
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4125008
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
title
Targeting DNA repair pathways for cancer treatment: what's new?
(English)
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stated in
Europe PubMed Central
PMC publication ID
4125008
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
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20 March 2020
author
Melissa Fishel
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3
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Europe PubMed Central
PMC publication ID
4125008
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
author name string
Mark R Kelley
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1
1 reference
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Europe PubMed Central
PMC publication ID
4125008
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
Derek Logsdon
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2
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Europe PubMed Central
PMC publication ID
4125008
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
language of work or name
English
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publication date
1 May 2014
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Europe PubMed Central
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4125008
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retrieved
20 March 2020
published in
Future Oncology
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stated in
Europe PubMed Central
PMC publication ID
4125008
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
volume
10
1 reference
stated in
Europe PubMed Central
PMC publication ID
4125008
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
4125008
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
page(s)
1215-1237
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Europe PubMed Central
PMC publication ID
4125008
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
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Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells
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Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms
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Hsp90 modulates CAG repeat instability in human cells
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Homologous recombination in cancer development, treatment and development of drug resistance.
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PARP inhibition: PARP1 and beyond
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Human AP endonuclease 1 (APE1): from mechanistic insights to druggable target in cancer.
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5 July 2018
Synthetic lethality: a framework for the development of wiser cancer therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Identification of a small molecule inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Redox regulation of DNA repair: implications for human health and cancer therapeutic development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Coordination of DNA mismatch repair and base excision repair processing of chemotherapy and radiation damage for targeting resistant cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
DNA repair in mammalian cells: Base excision repair: the long and short of it.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
DNA-PK: the means to justify the ends?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
The many functions of APE1/Ref-1: not only a DNA repair enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Recent advances in Hsp90 inhibitors as antitumor agents
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Going ape as an approach to cancer therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Implications of apurinic/apyrimidinic endonuclease in reactive oxygen signaling response after cisplatin treatment of dorsal root ganglion neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
DNA repair proteins as molecular targets for cancer therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Inhibitors of DNA polymerase beta: activity and mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
DNA repair pathways as targets for cancer therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
The endless tale of non-homologous end-joining
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Mechanisms and functions of DNA mismatch repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Repair capacity for platinum-DNA adducts determines the severity of cisplatin-induced peripheral neuropathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
DNA repair in neurons: so if they don't divide what's to repair?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Genetic predictors of adverse radiotherapy effects: the Gene-PARE project
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
The human apurinic/apyrimidinic endonuclease-1 suppresses activation of poly(adp-ribose) polymerase-1 induced by DNA single strand breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
The life and death of DNA-PK.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
MGMT: its role in cancer aetiology and cancer therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Inhibition of nucleotide excision repair and sensitisation of cells to DNA cross-linking anticancer drugs by F 11782, a novel fluorinated epipodophylloid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Repair pathways for processing of 8-oxoguanine in DNA by mammalian cell extracts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4125008
retrieved
5 July 2018
Beyond PARP Inhibitors: Agents in Pipelines Target DNA Repair Mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.2217%2FFON.14.60
retrieved
21 January 2018
Inhibition of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors: comparison with nonconjugated inhibitors and effect on fotemustine and temozolomide-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.2217%2FFON.14.60
retrieved
21 January 2018
The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.2217%2FFON.14.60
retrieved
21 January 2018
Comparison of two chemotherapy-induced peripheral neuropathy measurement approaches in children
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.2217%2FFON.14.60
retrieved
21 January 2018
Mission therapeutics
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24947262
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.2217/FON.14.60
1 reference
stated in
Europe PubMed Central
PMC publication ID
4125008
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
PMC publication ID
4125008
1 reference
stated in
Europe PubMed Central
PMC publication ID
4125008
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
PubMed publication ID
24947262
1 reference
stated in
Europe PubMed Central
PMC publication ID
4125008
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947262%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
ResearchGate publication ID
263296423
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