(Q34015960)

30 July 2017

A requirement for sustained ERK signaling during thymocyte positive selection in vivo (English)

1 reference

30 July 2017

0 references

Timothy K Starr

2

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Kristin A. Hogquist

object named as

Kristin A Hogquist

series ordinal

3

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author name string

Lisa K McNeil

series ordinal

1

1 reference

PubMed ID

16174747

30 July 2017

language of work or name

English

0 references

publication date

8 September 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

1 reference

30 July 2017

102

1 reference

30 July 2017

13574-13579

1 reference

30 July 2017

38

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PubMed ID

16174747

describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1224638/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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5 July 2018

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BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

5 July 2018

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Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

5 July 2018

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Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

5 July 2018

1 reference

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Regulation of early lymphocyte development by E2A family proteins

5 July 2018

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RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.

5 July 2018

1 reference

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Positive and negative selection of T cells

5 July 2018

1 reference

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Id: a target of BMP signaling

5 July 2018

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Rare, structurally homologous self-peptides promote thymocyte positive selection

5 July 2018

1 reference

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Thymocyte development in early growth response gene 1-deficient mice

5 July 2018

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Molecular interpretation of ERK signal duration by immediate early gene products

5 July 2018

1 reference

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The function of E- and Id proteins in lymphocyte development

5 July 2018

1 reference

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

5 July 2018

1 reference

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Protein tyrosine phosphatases

5 July 2018

1 reference

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The cap-to-tail guide to mRNA turnover

5 July 2018

1 reference

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Signal strength in thymic selection and lineage commitment.

5 July 2018

1 reference

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Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

RasGRP is essential for mouse thymocyte differentiation and TCR signaling

5 July 2018

1 reference

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Extracellular signals and scores of phosphatases: all roads lead to MAP kinase

5 July 2018

1 reference

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A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Antigen-induced coreceptor down-regulation on thymocytes is not a result of apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

The helix-loop-helix transcription factors Id1 and Id3 have a functional role in control of cell division in human normal and neoplastic chondrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Induction of the early growth response (Egr) family of transcription factors during thymic selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

T cell receptor antagonist peptides induce positive selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Involvement of p21ras distinguishes positive and negative selection in thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Positive selection of T cells: rescue from programmed cell death and differentiation require continual engagement of the T cell receptor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

The majority of postselection CD4+ single-positive thymocytes requires the thymus to produce long-lived, functional T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Calcium oscillations regulate thymocyte motility during positive selection in the three-dimensional thymic environment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Cloning and characterization of Xenopus Id4 reveals differing roles for Id genes

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Notch signaling is involved in the regulation of Id3 gene transcription during Xenopus embryogenesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-beta

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Disruption of T cell signaling networks and development by Grb2 haploid insufficiency.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Early growth response (Egr)-1 gene induction in the thymus in response to TCR ligation during early steps in positive selection is not required for CD8 lineage commitment.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

MEK activity regulates negative selection of immature CD4+CD8+ thymocytes.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Selective requirement for MAP kinase activation in thymocyte differentiation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Positive selection of thymocytes involves sustained interactions with the thymic microenvironment.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224638

Degree of ERK activation influences both positive and negative thymocyte selection

29 October 2018

1 reference

12 December 2020

Assays of thymic selection. Fetal thymus organ culture and in vitro thymocyte dulling assay

1 reference

12 December 2020

Co-regulation of the mitogen-activated protein kinase, extracellular signal-regulated kinase 1, and the 90-kDa ribosomal S6 kinase in PC12 cells. Distinct effects of the neurotrophic factor, nerve growth factor, and the mitogenic factor, epidermal g

1 reference

12 December 2020

Normal sequence of phenotypic transitions in one cohort of 5-bromo-2'-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression

1 reference

12 December 2020

Production, selection, and maturation of thymocytes with high surface density of TCR

1 reference

12 December 2020

Growth and differentiation proceeds normally in cells deficient in the immediate early gene NGFI-A

1 reference

12 December 2020

Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)

1 reference

12 December 2020

Slow accumulation of active mitogen-activated protein kinase during thymocyte differentiation regulates the temporal pattern of transcription factor gene expression

1 reference

12 December 2020

Duration and Strength of Extracellular Signal-Regulated Kinase Signals Are Altered During Positive Versus Negative Thymocyte Selection

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0505110102

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference

PubMed ID

16174747