(Q34022861)

30 July 2017

title

MAF mediates crosstalk between Ras-MAPK and mTOR signaling in NF1. (English)

1 reference

30 July 2017

A Jegga

7

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author name string

M E Brundage

1

1 reference

30 July 2017

P Tandon

2

1 reference

30 July 2017

D W Eaves

3

1 reference

30 July 2017

J P Williams

4

1 reference

30 July 2017

S J Miller

5

1 reference

30 July 2017

R H Hennigan

6

1 reference

30 July 2017

T P Cripe

8

1 reference

30 July 2017

N Ratner

9

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30 July 2017

language of work or name

English

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publication date

10 February 2014

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30 July 2017

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

Oncogene

1 reference

30 July 2017

volume

33

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30 July 2017

issue

49

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30 July 2017

page(s)

5626-5636

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describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4127377/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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RAS/MEK-independent gene expression reveals BMP2-related malignant phenotypes in the Nf1-deficient MPNST.

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5 July 2018

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A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition

5 July 2018

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5 July 2018

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Prognostic significance of AKT/mTOR and MAPK pathways and antitumor effect of mTOR inhibitor in NF1-related and sporadic malignant peripheral nerve sheath tumors.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

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The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors

5 July 2018

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NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome

5 July 2018

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

5 July 2018

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5 July 2018

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Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene

5 July 2018

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Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis

5 July 2018

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DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

5 July 2018

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Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor

5 July 2018

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Mechanisms in the pathogenesis of malignant tumours in neurofibromatosis type 1.

5 July 2018

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5 July 2018

A new MAFia in cancer.

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Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential.

5 July 2018

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Somatic mutations affect key pathways in lung adenocarcinoma

5 July 2018

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Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

5 July 2018

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Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors

5 July 2018

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TORC1 is essential for NF1-associated malignancies

5 July 2018

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Integration of high-resolution array comparative genomic hybridization analysis of chromosome 16q with expression array data refines common regions of loss at 16q23-qter and identifies underlying candidate tumor suppressor genes in prostate cancer

5 July 2018

1 reference

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5 July 2018

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A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene

5 July 2018

1 reference

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Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/small Maf by antirheumatic gold(I) compounds

5 July 2018

1 reference

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Mouse tumor model for neurofibromatosis type 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

The regulation of AP-1 activity by mitogen-activated protein kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

The transcription factor c-Maf controls touch receptor development and function.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

Nfl gene inactivation in acute myeloid leukemia cells confers cytarabine resistance through MAPK and mTOR pathways

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

Cell context reveals a dual role for Maf in oncogenesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

Hyperactivation of protein kinase B and ERK have discrete effects on survival, proliferation, and cytokine expression in Nf1-deficient myeloid cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127377

Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis

29 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2013.506

Neoplasms with schwannian differentiation express transcription factors known to regulate normal schwann cell development

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2013.506

Neural crest development is regulated by the transcription factor Sox9.

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2013.506

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.506

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference