(Q34038901)

30 July 2017

Immunity, inflammation and cancer: a leading role for adenosine (English)

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30 July 2017

3

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30 July 2017

Corrado Blandizzi

2

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author name string

Luca Antonioli

series ordinal

1

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30 July 2017

György Haskó

series ordinal

4

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30 July 2017

language of work or name

English

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publication date

14 November 2013

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30 July 2017

Nature Reviews Cancer

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30 July 2017

13

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30 July 2017

12

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30 July 2017

842-857

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https://scigraph.springernature.com/pub.10.1038/nrc3613

30 July 2017

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cites work

A2A adenosine receptor protects tumors from antitumor T cells.

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Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

31 March 2020

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Regulation of enteric functions by adenosine: pathophysiological and pharmacological implications.

31 March 2020

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Biological functions of ecto-enzymes in regulating extracellular adenosine levels in neoplastic and inflammatory disease states

31 March 2020

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Adenosine: an endogenous regulator of innate immunity

31 March 2020

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Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function.

31 March 2020

1 reference

Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death.

31 March 2020

1 reference

Adenosine signaling during acute and chronic disease states

31 March 2020

1 reference

Hypoxia-adenosinergic immunosuppression: tumor protection by T regulatory cells and cancerous tissue hypoxia

31 March 2020

1 reference

Regulation of macrophage function by adenosine

31 March 2020

1 reference

Host A(2B) adenosine receptors promote carcinoma growth

31 March 2020

1 reference

Tumor-promoting functions of adenosine

31 March 2020

1 reference

Adenosine metabolism and cancer. Focus on “Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatases and reducing ERK1/2 activity via a novel pathway”

31 March 2020

1 reference

Adenosine receptors: G protein-mediated signalling and the role of accessory proteins.

31 March 2020

1 reference

Extracellular nucleotides and adenosine independently activate AMP-activated protein kinase in endothelial cells: involvement of P2 receptors and adenosine transporters.

31 March 2020

1 reference

Adenosine kinase: exploitation for therapeutic gain

31 March 2020

1 reference

Methionine metabolism and liver disease

31 March 2020

1 reference

Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders.

31 March 2020

1 reference

CD39 and CD73 in immunity and inflammation

31 March 2020

1 reference

The equilibrative nucleoside transporter family, SLC29

31 March 2020

1 reference

The concentrative nucleoside transporter family, SLC28

31 March 2020

1 reference

Inflammation and cancer: back to Virchow?

31 March 2020

1 reference

Altered purinergic signaling in CD73-deficient mice inhibits tumor progression

31 March 2020

1 reference

Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production.

31 March 2020

1 reference

A glance at adenosine receptors: novel target for antitumor therapy

31 March 2020

1 reference

Adenosine receptors and cancer.

31 March 2020

1 reference

Immune cell regulation by autocrine purinergic signalling

31 March 2020

1 reference

Macrophage plasticity and polarization in tissue repair and remodelling

31 March 2020

1 reference

Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms

31 March 2020

1 reference

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

31 March 2020

1 reference

Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy

31 March 2020

1 reference

Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanism

31 March 2020

1 reference

Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis

31 March 2020

1 reference

Ecto-5'-nucleotidase (CD73) decreases mortality and organ injury in sepsis

31 March 2020

1 reference

Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms

31 March 2020

1 reference

A2A adenosine receptors and C/EBPbeta are crucially required for IL-10 production by macrophages exposed to Escherichia coli

31 March 2020

1 reference

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

31 March 2020

1 reference

Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin

31 March 2020

1 reference

An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors

31 March 2020

1 reference

Adenosine up-regulates vascular endothelial growth factor in human macrophages

31 March 2020

1 reference

Adenosine A2a receptor-mediated, normoxic induction of HIF-1 through PKC and PI-3K-dependent pathways in macrophages.

31 March 2020

1 reference

Synergistic up-regulation of vascular endothelial growth factor (VEGF) expression in macrophages by adenosine A2A receptor agonists and endotoxin involves transcriptional regulation via the hypoxia response element in the VEGF promoter

31 March 2020

1 reference

Adenosine receptors in regulation of dendritic cell differentiation and function

31 March 2020

1 reference

HIF-dependent induction of adenosine receptor A2b skews human dendritic cells to a Th2-stimulating phenotype under hypoxia

31 March 2020

1 reference

Adenosine A2B receptor blockade slows growth of bladder and breast tumors

31 March 2020

1 reference

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

31 March 2020

1 reference

Myeloid-derived suppressor cells: linking inflammation and cancer

31 March 2020

1 reference

Adenosinergic regulation of the expansion and immunosuppressive activity of CD11b+Gr1+ cells

31 March 2020

1 reference

Failure of immune homeostasis -- the consequences of under and over reactivity

31 March 2020

1 reference

Regulatory T cells and immune tolerance

31 March 2020

1 reference

Targeting regulatory T cells in cancer

31 March 2020

1 reference

Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells

31 March 2020

1 reference

Separation of human CD4+CD39+ T cells by magnetic beads reveals two phenotypically and functionally different subsets

31 March 2020

1 reference

Much ado about adenosine: adenosine synthesis and function in regulatory T cell biology

31 March 2020

1 reference

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

31 March 2020

1 reference

CD73 and adenosine generation in the creation of regulatory microenvironments.

31 March 2020

1 reference

Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness

31 March 2020

1 reference

Adenosine and prostaglandin E2 cooperate in the suppression of immune responses mediated by adaptive regulatory T cells

31 March 2020

1 reference

Increased ectonucleotidase expression and activity in regulatory T cells of patients with head and neck cancer

31 March 2020

1 reference

CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice

31 March 2020

1 reference

CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes

31 March 2020

1 reference

Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice

31 March 2020

1 reference

Extracellular adenosine triphosphate and adenosine in cancer.

31 March 2020

1 reference

ENTPD1/CD39 is a promising therapeutic target in oncology

31 March 2020

1 reference

Purinergic signalling and cancer

31 March 2020

1 reference

CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression

31 March 2020

1 reference

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

31 March 2020

1 reference

CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer

31 March 2020

1 reference

CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice

31 March 2020

1 reference

CD73-deficient mice are resistant to carcinogenesis

31 March 2020

1 reference

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

31 March 2020

1 reference

CD73 is involved in lymphocyte binding to the endothelium: characterization of lymphocyte-vascular adhesion protein 2 identifies it as CD73

31 March 2020

1 reference

CD73 engagement promotes lymphocyte binding to endothelial cells via a lymphocyte function-associated antigen-1-dependent mechanism.

31 March 2020

1 reference

CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis

31 March 2020

1 reference

Stat3 and Gfi-1 Transcription Factors Control Th17 Cell Immunosuppressive Activity via the Regulation of Ectonucleotidase Expression

31 March 2020

1 reference

2-chloroadenosine stimulates granule exocytosis from mouse natural killer cells: evidence for signal transduction through a novel extracellular receptor

31 March 2020

1 reference

Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells

31 March 2020

1 reference

Adenosine-mediated inhibition of the cytotoxic activity and cytokine production by activated natural killer cells

31 March 2020

1 reference

Adenosine-mediated inhibition of cytotoxic activity and cytokine production by IL-2/NKp46-activated NK cells: involvement of protein kinase A isozyme I (PKA I).

31 March 2020

1 reference

Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors

31 March 2020

1 reference

Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer

31 March 2020

1 reference

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

31 March 2020

1 reference

Targeting CD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs

31 March 2020

1 reference

Methotrexate--how does it really work?

31 March 2020

1 reference

Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.

31 March 2020

1 reference

Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms

31 March 2020

1 reference

Evolving functions of endothelial cells in inflammation

31 March 2020

1 reference

Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors

31 March 2020

1 reference

Tumor angiogenesis: molecular pathways and therapeutic targets

31 March 2020

1 reference

Ecto-5'-nucleotidase (CD73) promotes tumor angiogenesis

31 March 2020

1 reference

Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate

31 March 2020

1 reference

Disordered purinergic signaling inhibits pathological angiogenesis in cd39/Entpd1-null mice

31 March 2020

1 reference

A(2B) adenosine receptors in immunity and inflammation.

31 March 2020

1 reference

The A2B adenosine receptor protects against inflammation and excessive vascular adhesion

31 March 2020

1 reference

A2B adenosine receptor dampens hypoxia-induced vascular leak

31 March 2020

1 reference

Adenosine A2A receptor is a unique angiogenic target of HIF-2alpha in pulmonary endothelial cells.

31 March 2020

1 reference

Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells

31 March 2020

1 reference

A(2B) and A(3) adenosine receptors modulate vascular endothelial growth factor and interleukin-8 expression in human melanoma cells treated with etoposide and doxorubicin.

31 March 2020

1 reference

Adenosine modulates vascular endothelial growth factor expression via hypoxia-inducible factor-1 in human glioblastoma cells

31 March 2020

1 reference

A3 adenosine receptors modulate hypoxia-inducible factor-1alpha expression in human A375 melanoma cells

31 March 2020

1 reference

Tumor regression of B16F10 melanoma in vivo by prevention of neovascularization: study on theophylline

31 March 2020

1 reference

RNA interference of ecto-5'-nucleotidase (CD73) inhibits human breast cancer cell growth and invasion

31 March 2020

1 reference

Ecto-5'-nucleotidase/CD73 inhibition by quercetin in the human U138MG glioma cell line

31 March 2020

1 reference

The role of ecto-5'-nucleotidase/CD73 in glioma cell line proliferation

31 March 2020

1 reference

Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway

31 March 2020

1 reference

Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: implications for cancer cell behavior

31 March 2020

1 reference

Differential expression of human nucleoside transporters in normal and tumor tissue

31 March 2020

1 reference

Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy

31 March 2020

1 reference

Nucleoside analogues: mechanisms of drug resistance and reversal strategies.

31 March 2020

1 reference

EGFR antagonists in cancer treatment

31 March 2020

1 reference

Cause and consequences of genetic and epigenetic alterations in human cancer.

31 March 2020

1 reference

Cyclins and cell cycle checkpoints

31 March 2020

1 reference

Differential effect of adenosine on tumor and normal cell growth: focus on the A3 adenosine receptor

31 March 2020

1 reference

RNA interference targeting of A1 receptor-overexpressing breast carcinoma cells leads to diminished rates of cell proliferation and induction of apoptosis

31 March 2020

1 reference

Adenosine A1 receptor, a target and regulator of estrogen receptoralpha action, mediates the proliferative effects of estradiol in breast cancer

31 March 2020

1 reference

Hypoxia-inducible adenosine A2B receptor modulates proliferation of colon carcinoma cells

31 March 2020

1 reference

A2B adenosine receptor blockade inhibits growth of prostate cancer cells.

31 March 2020

1 reference

An adenosine analog (IB-MECA) inhibits anchorage-dependent cell growth of various human breast cancer cell lines

31 March 2020

1 reference

Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells.

31 March 2020

1 reference

A3 adenosine receptor activation in melanoma cells: association between receptor fate and tumor growth inhibition

31 March 2020

1 reference

A3 adenosine receptor activation inhibits cell proliferation via phosphatidylinositol 3-kinase/Akt-dependent inhibition of the extracellular signal-regulated kinase 1/2 phosphorylation in A375 human melanoma cells

31 March 2020

1 reference

An agonist to the A3 adenosine receptor inhibits colon carcinoma growth in mice via modulation of GSK-3 beta and NF-kappa B.

31 March 2020

1 reference

Adenosine acts as an inhibitor of lymphoma cell growth: a major role for the A3 adenosine receptor

31 March 2020

1 reference

Inhibition of primary colon carcinoma growth and liver metastasis by the A3 adenosine receptor agonist CF101

31 March 2020

1 reference

Adenosine modulates cell growth in the human breast cancer cells via adenosine receptors

31 March 2020

1 reference

Resistance of muscle to tumor metastases: a role for a3 adenosine receptor agonists

31 March 2020

1 reference

The A3 adenosine receptor as a new target for cancer therapy and chemoprotection

31 March 2020

1 reference

Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway.

31 March 2020

1 reference

Evidence for involvement of Wnt signaling pathway in IB-MECA mediated suppression of melanoma cells

31 March 2020

1 reference

The antitumor effect of LJ-529, a novel agonist to A3 adenosine receptor, in both estrogen receptor-positive and estrogen receptor-negative human breast cancers

31 March 2020

1 reference

Cl-IB-MECA inhibits human thyroid cancer cell proliferation independently of A3 adenosine receptor activation

31 March 2020

1 reference

Apoptotic pathways in tumor progression and therapy

31 March 2020

1 reference

Hallmarks of Cancer: The Next Generation

31 March 2020

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Mitochondria and cell death: outer membrane permeabilization and beyond

31 March 2020

1 reference

Apoptosis in cancer: from pathogenesis to treatment

31 March 2020

1 reference

Tuning of apoptosis-mediator gene transcription in HepG2 human hepatoma cells through an adenosine signal

31 March 2020

1 reference

Adenosine suppresses CW2 human colonic cancer growth by inducing apoptosis via A(1) adenosine receptors

31 March 2020

1 reference

Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li‐7A cells via the A3 adenosine receptor

31 March 2020

1 reference

A novel adenosine analog, thio-Cl-IB-MECA, induces G0/G1 cell cycle arrest and apoptosis in human promyelocytic leukemia HL-60 cells

31 March 2020

1 reference

p53-Independent induction of Fas and apoptosis in leukemic cells by an adenosine derivative, Cl-IB-MECA.

31 March 2020

1 reference

P-glycoprotein mediates resistance to A3 adenosine receptor agonist 2-chloro-N6-(3-iodobenzyl)-adenosine-5'-n-methyluronamide in human leukemia cells

31 March 2020

1 reference

CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver

31 March 2020

1 reference

Cl-IB-MECA enhances TRAIL-induced apoptosis via the modulation of NF-kappaB signalling pathway in thyroid cancer cells.

31 March 2020

1 reference

Extracellular adenosine induces apoptosis in Caco-2 human colonic cancer cells by activating caspase-9/-3 via A(2a) adenosine receptors

31 March 2020

1 reference

A3 adenosine receptor-mediated p53-dependent apoptosis in Lu-65 human lung cancer cells

31 March 2020

1 reference

Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3.

31 March 2020

1 reference

Intracellularly transported adenosine induces apoptosis in HuH-7 human hepatoma cells by downregulating c-FLIP expression causing caspase-3/-8 activation

31 March 2020

1 reference

Adenosine-induced caspase-3 activation by tuning Bcl-XL/DIABLO/IAP expression in HuH-7 human hepatoma cells

31 March 2020

1 reference

AMP converted from intracellularly transported adenosine upregulates p53 expression to induce malignant pleural mesothelioma cell apoptosis

31 March 2020

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Adenosine activates AMPK to phosphorylate Bcl-XL responsible for mitochondrial damage and DIABLO release in HuH-7 cells

31 March 2020

1 reference

A(1) adenosine receptor signal and AMPK involving caspase-9/-3 activation are responsible for adenosine-induced RCR-1 astrocytoma cell death

31 March 2020

1 reference

Cell death independent of caspases: a review.

31 March 2020

1 reference

Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death?

31 March 2020

1 reference

A(3) adenosine receptor mediates apoptosis in 5637 human bladder cancer cells by G(q) protein/PKC-dependent AIF upregulation.

31 March 2020

1 reference

AMID mediates adenosine-induced caspase-independent HuH-7 cell apoptosis

31 March 2020

1 reference

A3 adenosine receptor mediates apoptosis in in vitro RCC4-VHL human renal cancer cells by up-regulating AMID expression

31 March 2020

1 reference

Adenosine induces apoptosis in SBC-3 human lung cancer cells through A(3) adenosine receptor-dependent AMID upregulation

31 March 2020

1 reference

AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis

31 March 2020

1 reference

Intracellularly transported adenosine induces apoptosis in [corrected] MCF-7 human breast cancer cells by accumulating AMID in the nucleus

31 March 2020

1 reference

Molecular basis of metastasis.

31 March 2020

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Permissive role of endothelin receptors in tumor metastasis

31 March 2020

1 reference

Molecular networks that regulate cancer metastasis

31 March 2020

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Impact of CD39 and purinergic signalling on the growth and metastasis of colorectal cancer

31 March 2020

1 reference

Overexpression of Ecto-5'-Nucleotidase (CD73) promotes T-47D human breast cancer cells invasion and adhesion to extracellular matrix

31 March 2020

1 reference

Ecto-5′-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells

31 March 2020

1 reference

Characterization of ectonucleotidases in human medulloblastoma cell lines: ecto-5'NT/CD73 in metastasis as potential prognostic factor

31 March 2020

1 reference

Gene expression profiling of tumor xenografts: In vivo analysis of organ‐specific metastasis

31 March 2020

1 reference

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis

31 March 2020

1 reference

An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering

31 March 2020

1 reference

Exosomes drive premetastatic niche formation

31 March 2020

1 reference

Cancer and inflammation: an old intuition with rapidly evolving new concepts

31 March 2020

1 reference

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

31 March 2020

1 reference

Immunity, Inflammation, and Cancer

31 March 2020

1 reference

Helicobacter pylori in gastric malignancies

31 March 2020

1 reference

Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma

31 March 2020

1 reference

Human papillomavirus and cancer: the epidemiological evidence

31 March 2020

1 reference

Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8: a new virus in human pathology.

31 March 2020

1 reference

Inflammation, DNA methylation and colitis-associated cancer

31 March 2020

1 reference

Mechanistic links between COPD and lung cancer

31 March 2020

1 reference

Inflammation in prostate carcinogenesis

31 March 2020

1 reference

Neutralizing tumor-promoting chronic inflammation: a magic bullet?

31 March 2020

1 reference

Smoldering and polarized inflammation in the initiation and promotion of malignant disease

31 March 2020

1 reference

Involvement of G-protein betagamma subunits in coupling the adenosine A1 receptor to phospholipase C in transfected CHO cells

31 March 2020

1 reference

Human adenosine A(1), A(2A), A(2B), and A(3) receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2

31 March 2020

1 reference

Activation of mitogen-activated protein kinase by the A(2A)-adenosine receptor via a rap1-dependent and via a p21(ras)-dependent pathway

31 March 2020

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MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases

31 March 2020

1 reference

Stimulation of the mitogen-activated protein kinase via the A2A-adenosine receptor in primary human endothelial cells

31 March 2020

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Signalling from adenosine receptors to mitogen-activated protein kinases

31 March 2020

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The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38.

31 March 2020

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Adenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated process

31 March 2020

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Regulation of p42/p44 mitogen-activated protein kinase by the human adenosine A3 receptor in transfected CHO cells

31 March 2020

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Involvement of mitogen protein kinase cascade in agonist-mediated human A(3) adenosine receptor regulation

31 March 2020

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Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth

31 March 2020

1 reference

Adenosine A(3) receptor suppresses prostate cancer metastasis by inhibiting NADPH oxidase activity

31 March 2020

1 reference

Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type

31 March 2020

1 reference

Anti-CD73 therapy impairs tumor angiogenesis

31 March 2020

1 reference

Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma

31 March 2020

1 reference

Adenosine receptor antagonism causes inhibition of angiogenic activity of human ovarian cancer cells.

31 March 2020

1 reference

12 December 2020

Chronic inflammation and cancer: the role of the mitochondria.

1 reference

12 December 2020

The A3 adenosine receptor agonist CF102 induces apoptosis of hepatocellular carcinoma via de-regulation of the Wnt and NF-kappaB signal transduction pathways.

1 reference

12 December 2020

Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo.

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12 December 2020

Chronic inflammation and cancer

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12 December 2020

Adenosine in fibrosis.

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12 December 2020

Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review).

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12 December 2020

A microRNA component of the neoplastic microenvironment: microregulators with far-reaching impact.

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12 December 2020

Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice.

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12 December 2020

Role of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinase kinase in adenosine A2B receptor-mediated interleukin-8 production in human mast cells

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12 December 2020

Crosstalk between adenosine receptor (A2A isoform) and ERalpha mediates ethanol action in MCF-7 breast cancer cells.

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12 December 2020

An adenosine analogue, IB-MECA, down-regulates estrogen receptor alpha and suppresses human breast cancer cell proliferation

1 reference

12 December 2020

A(2a) adenosine receptor mediates HepG2 cell apoptosis by downregulating Bcl-X(L) expression and upregulating Bid expression

1 reference

12 December 2020

Adenosine inhibits the adhesion of anti-CD3-activated killer lymphocytes to adenocarcinoma cells through an A3 receptor

1 reference

12 December 2020

The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine

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12 December 2020

cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells

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12 December 2020

Natural killer cells: role in local tumor growth and metastasis

1 reference

12 December 2020

Role of tumour-associated macrophages in cancer-related inflammation

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC3613

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference