(Q34041770)

30 July 2017

title

Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma (English)

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30 July 2017

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10

Ernst J Kuipers

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30 July 2017

7

Peter D Siersema

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30 July 2017

Anouk van de Winkel

1

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30 July 2017

Vivianda Menke

2

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30 July 2017

Astrid Capello

3

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30 July 2017

Leon M G Moons

4

1 reference

30 July 2017

Raymond G J Pot

5

1 reference

30 July 2017

Herman van Dekken

6

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30 July 2017

Johannes G Kusters

8

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30 July 2017

Luc J W van der Laan

9

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30 July 2017

publication date

6 October 2011

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30 July 2017

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30 July 2017

volume

11

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30 July 2017

page(s)

108

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Creative Commons Attribution 2.0 Generic

30 July 2017

copyright license

start time

6 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Clinical puzzle: Barrett's oesophagus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Role of human pregnane X receptor in tamoxifen- and 4-hydroxytamoxifen-mediated CYP3A4 induction in primary human hepatocytes and LS174T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Intestinal drug transporter expression and the impact of grapefruit juice in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Pregnane X receptor: promiscuous regulator of detoxification pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Bile acids and Barrett's oesophagus: a sine qua non or coincidence?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

MRP2 and 3 in health and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Increasing incidence of Barrett's oesophagus in the general population

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Enterohepatic bile salt transporters in normal physiology and liver disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Experimental Evidence for Mutagenic Potential of Duodenogastric Juice on Barrett’s Esophagus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Importance of bile reflux in Barrett's esophagus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Failure of oesophageal acid control in candidates for Barrett's oesophagus reversal on a very high dose of proton pump inhibitor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Reflux disease and Barrett's esophagus.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204292

Barrett's esophagus-is it bad for your health?

5 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-230X-11-108

The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-230X-11-108

Screening for polymorphisms in the PXR gene in a Dutch population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-230X-11-108

Promiscuous regulator of xenobiotic removal

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-230X-11-108

ABC transporter regulation by bile acids: where PXR meets FXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-230X-11-108

Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-230X-11-108

[[Inflammation and drug metabolism: NF-kappB and the CAR and PXR xeno-receptors].

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-230X-11-108

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-230X-11-108

Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-230X-11-108

Barrett's esophagus. A prevalent, occult complication of gastroesophageal reflux disease

21 January 2018

1 reference

12 December 2020

1 reference

12 December 2020

COX-2 CA-haplotype is a risk factor for the development of esophageal adenocarcinoma

1 reference

12 December 2020

Effects of acid and bile salts on the rabbit esophageal mucosa

1 reference

12 December 2020

Polymorphisms in the steroid and xenobiotic receptor gene influence survival in primary sclerosing cholangitis

1 reference

12 December 2020

Acid and bile reflux in Barrett's esophagus: a tale of two evils

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-230X-11-108

1 reference

Dimensions Publication ID

30 July 2017

1030745381

0 references

Fatcat ID

release_ahyzb2lpwrhfne26zdqrmo325i

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ahyzb2lpwrhfne26zdqrmo325i

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3204292

1 reference

30 July 2017

1 reference