(Q34082661)

30 July 2017

Dimerization of HIV-1 protease occurs through two steps relating to the mechanism of protease dimerization inhibition by darunavir (English)

1 reference

30 July 2017

1 reference

Hironori Hayashi

1

1 reference

30 July 2017

Nobutoki Takamune

2

1 reference

30 July 2017

Takashi Nirasawa

3

1 reference

30 July 2017

Manabu Aoki

4

1 reference

30 July 2017

Yoshihiko Morishita

5

1 reference

30 July 2017

Debananda Das

6

1 reference

30 July 2017

Yasuhiro Koh

7

1 reference

30 July 2017

Arun K Ghosh

8

1 reference

30 July 2017

Shogo Misumi

9

1 reference

30 July 2017

Hiroaki Mitsuya

10

1 reference

30 July 2017

language of work or name

English

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publication date

4 August 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

1 reference

30 July 2017

111

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30 July 2017

33

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30 July 2017

12234-12239

1 reference

How Does Darunavir Prevent HIV-1 Protease Dimerization?

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

GRL-0519, a novel oxatricyclic ligand-containing nonpeptidic HIV-1 protease inhibitor (PI), potently suppresses replication of a wide spectrum of multi-PI-resistant HIV-1 variants in vitro.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Kinetic characterization of the critical step in HIV-1 protease maturation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Loss of the protease dimerization inhibition activity of tipranavir (TPV) and its association with the acquisition of resistance to TPV by HIV-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Activity of human immunodeficiency virus type 1 protease inhibitors against the initial autocleavage in Gag-Pol polyprotein processing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Terminal Interface Conformations Modulate Dimer Stability Prior to Amino Terminal Autoprocessing of HIV-1 Protease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Loss of protease dimerization inhibition activity of darunavir is associated with the acquisition of resistance to darunavir by HIV-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Inhibition of autoprocessing of natural variants and multidrug resistant mutant precursors of HIV-1 protease by clinical inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

In vitro selection of highly darunavir-resistant and replication-competent HIV-1 variants by using a mixture of clinical HIV-1 isolates resistant to multiple conventional protease inhibitors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Interactions of different inhibitors with active-site aspartyl residues of HIV-1 protease and possible relevance to pepsin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

HIV-1 protease: structure, dynamics, and inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Inhibition of HIV-1 replication by a peptide dimerization inhibitor of HIV-1 protease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Small-molecule dimerization inhibitors of wild-type and mutant HIV protease: a focused library approach

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Initial cleavage of the human immunodeficiency virus type 1 GagPol precursor by its activated protease occurs by an intramolecular mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Systematic mutational analysis of the active-site threonine of HIV-1 proteinase: rethinking the "fireman's grip" hypothesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Trans-dominant inhibitory human immunodeficiency virus type 1 protease monomers prevent protease activation and virion maturation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Comparison of the crystal structures and intersubunit interactions of human immunodeficiency and Rous sarcoma virus proteases.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Synthetic "interface" peptides alter dimeric assembly of the HIV 1 and 2 proteases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Revisiting monomeric HIV-1 protease. Characterization and redesign for improved properties

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1400027111

Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1400027111

Binding kinetics of darunavir to human immunodeficiency virus type 1 protease explain the potent antiviral activity and high genetic barrier

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1400027111

Application of electrospray ionization mass spectrometry for studying human immunodeficiency virus protein complexes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142999

Mutational and structural studies aimed at characterizing the monomer of HIV-1 protease and its precursor

28 October 2018

1 reference

12 December 2020

Determination of monoisotopic masses and ion populations for large biomolecules from resolved isotopic distributions

1 reference

12 December 2020

The structural stability of the HIV-1 protease

1 reference

12 December 2020

Probing the role of interfacial residues in a dimerization inhibitor of HIV-1 protease

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1400027111

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tbzoai2a5jd3xjgagmqmbcdgdi

30 July 2022

release_tbzoai2a5jd3xjgagmqmbcdgdi

ADS bibcode

2014PNAS..11112234H

0 references

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tbzoai2a5jd3xjgagmqmbcdgdi

30 July 2022

https://api.fatcat.wiki/v0/release/tbzoai2a5jd3xjgagmqmbcdgdi

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/tbzoai2a5jd3xjgagmqmbcdgdi

1 reference

30 July 2022