(Q34095986)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

High-throughput fluorescence polarization assay for chemical library screening against anti-apoptotic Bcl-2 family member Bfl-1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

2

1 reference

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18 January 2020

author name string

Dayong Zhai

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Eduard Sergienko

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Russell Dahl

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Xochella Chan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Brock Brown

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Justin Rascon

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Andrew Hurder

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Ying Su

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Thomas D Y Chung

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Chaofang Jin

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Paul Diaz

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

John C Reed

13

1 reference

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18 January 2020

publication date

7 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomolecular Screening

18 January 2020

published in

1 reference

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18 January 2020

volume

17

1 reference

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18 January 2020

issue

3

1 reference

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18 January 2020

page(s)

350-360

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

The BCL-2 protein family: opposing activities that mediate cell death

18 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

21 January 2018

The BCL-2 family reunion

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

How the Bcl-2 family of proteins interact to regulate apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Essential role of the prosurvival bcl-2 homologue A1 in mast cell survival after allergic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Constitutive expression of bcl-2 in B cells causes a lethal form of lupuslike autoimmune disease after induction of neonatal tolerance to H-2b alloantigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Downregulation of Bfl-1 protein expression sensitizes malignant B cells to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

High expression of bfl-1 contributes to the apoptosis resistant phenotype in B-cell chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Apoptosis-based therapies for hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Inhibition of Bfl-1 with N-aryl maleimides

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

IgE-receptor activation induces survival and Bfl-1 expression in human mast cells but not basophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

Overexpression of the antiapoptotic gene Bfl-1 in B cells from patients with familial systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

A1/Bfl-1 expression is restricted to TCR engagement in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057111429372

21 January 2018

Identifiers

DOI

10.1177/1087057111429372

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156224%20AND%20SRC:MED&resulttype=core&format=json

release_eblohrwkzjcepdqxuxr37eevbi

18 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/eblohrwkzjcepdqxuxr37eevbi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference