(Q34100703)

31 July 2017

title

Hippocampal proliferation is increased in presymptomatic Parkinson's disease and due to microglia (English)

1 reference

31 July 2017

0 references

1 reference

2

Benjamin Drukarch

1 reference

31 July 2017

Karlijn J Doorn

1

1 reference

31 July 2017

Anne-Marie van Dam

series ordinal

3

1 reference

31 July 2017

Paul J Lucassen

series ordinal

4

1 reference

31 July 2017

publication date

14 August 2014

1 reference

31 July 2017

1 reference

31 July 2017

volume

2014

1 reference

31 July 2017

page(s)

959154

1 reference

Creative Commons Attribution 3.0 Unported

31 July 2017

copyright license

start time

1 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Proliferation in the Alzheimer hippocampus is due to microglia, not astroglia, and occurs at sites of amyloid deposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson's disease patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Harnessing neurogenesis for the possible treatment of Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Increased precursor cell proliferation after deep brain stimulation for Parkinson's disease: a human study.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Neurogenesis in the striatum of the adult human brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Increased amoeboid microglial density in the olfactory bulb of Parkinson's and Alzheimer's patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

A quantitative study of α-synuclein pathology in fifteen cases of dementia associated with Parkinson disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Regulation of microglial proliferation during chronic neurodegeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Parkinson's disease and alpha synuclein: is Parkinson's disease a prion-like disorder?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Adult neurogenesis in Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Emerging roles of microglial activation and non-motor symptoms in Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Prion-like spread of protein aggregates in neurodegeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Neurogenesis and progenitor cells in the adult human brain: a comparison between hippocampal and subventricular progenitor proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Patterns of α-synuclein pathology in incidental cases and clinical subtypes of Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Neuroinflammation in Parkinson's disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Immunohistological markers for proliferative events, gliogenesis, and neurogenesis within the adult hippocampus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Neurodegenerative disease and adult neurogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

The patients' perception of prodromal symptoms before the initial diagnosis of Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Microglia in the CNS: immigrants from another world

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

The epidemiology of dementia associated with Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Neurogenesis in substantia nigra of parkinsonian brains?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Mechanisms underlying inflammation in neurodegeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Destruction of dopaminergic neurons in the midbrain by 6-hydroxydopamine decreases hippocampal cell proliferation in rats: reversal by fluoxetine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Neurogenesis and Alzheimer's disease: Biology and pathophysiology in mice and men.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Brainstem pathology and non-motor symptoms in PD.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Dopaminergic modulation of neurogenesis in the subventricular zone of the adult brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

A functional role for adult hippocampal neurogenesis in spatial pattern separation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Clearance and deposition of extracellular alpha-synuclein aggregates in microglia.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Glial reactions in Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Adult neurogenesis: can analysis of cell cycle proteins move us "Beyond BrdU"?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Immunohistological markers for staging neurogenesis in adult hippocampus.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Synuclein activates microglia in a model of Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Dopamine and adult neurogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Cognitive decline correlates with neuropathological stage in Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Detection of presymptomatic Parkinson's disease: combining smell tests, transcranial sonography, and SPECT.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

MCM2 and Ki-67 expression in human lung adenocarcinoma: prognostic implications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Dopamine depletion impairs precursor cell proliferation in Parkinson disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Evidence for neurogenesis in the adult mammalian substantia nigra

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Staging of brain pathology related to sporadic Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Continuation of neurogenesis in the hippocampus of the adult macaque monkey

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Neurogenesis in the adult human hippocampus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Turnover of resident microglia in the normal adult mouse brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Cell cycle dependent expression and stability of the nuclear protein detected by Ki-67 antibody in HL-60 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

5 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Hippocampal abnormalities and memory deficits in Parkinson disease: a multimodal imaging study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Possibility for neurogenesis in substantia nigra of parkinsonian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Quantitative evaluation of the human subventricular zone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Minichromosome maintenance protein 2 is a reliable proliferative marker in breast carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Decreased numbers of progenitor cells but no response to antidepressant drugs in the hippocampus of elderly depressed patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Granule cell dispersion is not accompanied by enhanced neurogenesis in temporal lobe epilepsy patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Spatial and temporal patterns of cell division during early Xenopus embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

The window and mechanisms of major age-related decline in the production of new neurons within the dentate gyrus of the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Combination of 'idiopathic' REM sleep behaviour disorder and olfactory dysfunction as possible indicator for alpha-synucleinopathy demonstrated by dopamine transporter FP-CIT-SPECT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Impairment of in vivo calcium signaling in amyloid plaque-associated microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Dopaminergic nigrostriatal projections regulate neural precursor proliferation in the adult mouse subventricular zone

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Origin of the dopaminergic innervation of adult neurogenic areas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Cortical Lewy body pathology in the diagnosis of dementia.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147270

The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain

28 October 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Reply: Quantitative evaluation of the human subventricular zone

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Human Wild-Type α-Synuclein Impairs Neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F959154

Epidemiology of Parkinson's disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25197578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2014/959154

1 reference

31 July 2017

1 reference

31 July 2017

1 reference