(Q34104525)

31 July 2017

Combinatorial reshaping of the Candida antarctica lipase A substrate pocket for enantioselectivity using an extremely condensed library (English)

1 reference

31 July 2017

1 reference

0 references

Candida antarctica

1 reference

5

Jan-E Bäckvall

1 reference

31 July 2017

Anders G Sandström

1

1 reference

31 July 2017

Ylva Wikmark

series ordinal

2

1 reference

31 July 2017

Karin Engström

series ordinal

3

1 reference

31 July 2017

Jonas Nyhlén

series ordinal

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

16 December 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

31 July 2017

109

1 reference

31 July 2017

78-83

1 reference

31 July 2017

1

1 reference

Combinatorial alanine substitution enables rapid optimization of cytochrome P450BM3 for selective hydroxylation of large substrates

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Laboratory evolution of stereoselective enzymes: a prolific source of catalysts for asymmetric reactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

The alpha/beta-hydrolase fold 3DM database (ABHDB) as a tool for protein engineering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Iterative saturation mutagenesis accelerates laboratory evolution of enzyme stereoselectivity: rigorous comparison with traditional methods.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Consensus protein design without phylogenetic bias

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Structural classification by the Lipase Engineering Database: a case study of Candida antarctica lipase A

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Exploring protein fitness landscapes by directed evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Enzyme engineering for enantioselectivity: from trial-and-error to rational design?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Industrial biotechnology: tools and applications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Directed evolution drives the next generation of biocatalysts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Directed evolution of Candida antarctica lipase A using an episomaly replicating yeast plasmid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Advances in generating functional diversity for directed protein evolution.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Constructing and analyzing the fitness landscape of an experimental evolutionary process

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Addressing the numbers problem in directed evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

X-ray structure of Candida antarctica lipase A shows a novel lid structure and a likely mode of interfacial activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Empirical fitness landscapes reveal accessible evolutionary paths

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Computationally designed libraries of fluorescent proteins evaluated by preservation and diversity of function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Biased mutation-assembling: an efficient method for rapid directed evolution through simultaneous mutation accumulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

An episomal expression vector for screening mutant gene libraries in Pichia pastoris

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Improving enzyme properties: when are closer mutations better?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Mathematical expressions useful in the construction, description and evaluation of protein libraries.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

WebLogo: A Sequence Logo Generator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Conserved residue clustering and protein structure prediction.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Multiple sequence alignment with the Clustal series of programs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Directed enzyme evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Recombinant protein expression in Pichia pastoris

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Natural Selection and the Concept of a Protein Space

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Directed evolution of enantioselective enzymes: an unconventional approach to asymmetric catalysis in organic chemistry

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111537108

Construction of stabilized proteins by combinatorial consensus mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111537108

Enzymatic removal of carboxyl protecting groups. 1. Cleavage of the tert-butyl moiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111537108

Rapid creation of a novel protein function by in vitro coevolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111537108

Increased enantioselectivity by engineering bottleneck mutants in an esterase from Pseudomonas fluorescens

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111537108

A rapid and efficient method for multiple-site mutagenesis with a modified overlap extension PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111537108

A direct and efficient PAGE-mediated overlap extension PCR method for gene multiple-site mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111537108

Finding better protein engineering strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111537108

Directed evolution of an enantioselective lipase with broad substrate scope for hydrolysis of alpha-substituted esters

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Greatly reduced amino acid alphabets in directed evolution: making the right choice for saturation mutagenesis at homologous enzyme positions

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252943

Charge distribution from a simple molecular orbital type calculation and non-bonding interaction terms in the force field MAB

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22178758

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expanding the range of substrate acceptance of enzymes: combinatorial active-site saturation test

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22178758

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1111537108

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference