(Q34119497)

31 July 2017

Neuroprotection by caspase inhibitors (English)

1 reference

31 July 2017

Braun JS

1

1 reference

31 July 2017

Tuomanen EI

series ordinal

2

1 reference

31 July 2017

Cleveland JL

series ordinal

3

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 October 1999

1 reference

Expert Opinion on Investigational Drugs

31 July 2017

1 reference

31 July 2017

8

1 reference

31 July 2017

10

1 reference

31 July 2017

1599-1610

1 reference

Human ICE/CED-3 protease nomenclature

31 July 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Structure and mechanism of interleukin-1 beta converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

21 January 2018

Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Caspases: intracellular signaling by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Inhibition of human caspases by peptide-based and macromolecular inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Non-specific effects of methyl ketone peptide inhibitors of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Caspases: key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

IAP family proteins--suppressors of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Ischemia-induced neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

A caspase inhibitor blocks ischaemia-induced delayed neuronal death in the gerbil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Neuroprotection by a caspase inhibitor in acute bacterial meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Elevated central nervous system prostaglandins in human immunodeficiency virus-associated dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Apoptosis induced by HIV-1 infection of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Virus infection induces neuronal apoptosis: A comparison with trophic factor withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Inhibition of virus-induced neuronal apoptosis by Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Apoptotic neurodegeneration following trauma is markedly enhanced in the immature brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Regional calpain and caspase-3 proteolysis of alpha-spectrin after traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Apoptosis in adult retinal ganglion cells after axotomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Caspase inhibitors block the retinal ganglion cell death following optic nerve transection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Is apoptosis key in Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Translating cell biology into therapeutic advances in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Terminal dUTP nick end labeling (TUNEL) positive cells in the different regions of the brain in normal aging and Alzheimer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Evidence for apoptotic cell death in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Trinucleotide (CAG) repeat length is positively correlated with the degree of DNA fragmentation in Huntington's disease striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Kainate-induced apoptotic cell death in hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Apoptosis. Dead end for neurodegeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Apoptotic pathways: the roads to ruin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

Inhibition of ICE slows ALS in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1599

10.1517/13543784.8.10.1599

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference