(Q34124847)

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Differences in the expression of endogenous efflux transporters in MDR1-transfected versus wildtype cell lines affect P-glycoprotein mediated drug transport

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Differences in the expression of endogenous efflux transporters in MDR1-transfected versus wildtype cell lines affect P-glycoprotein mediated drug transport (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Konstantin Kuteykin-Teplyakov

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Carlos Luna-Tortós

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Kamila Ambroziak

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Wolfgang Löscher

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

0 references

publication date

1 July 2010

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

British Journal of Pharmacology

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Europe PubMed Central

PubMed publication ID

31 July 2017

160

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1453-1463

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

The antiepileptic drug topiramate is a substrate for human P-glycoprotein but not multidrug resistance proteins

1 reference

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5 July 2018

Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.

1 reference

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Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar

1 reference

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5 July 2018

Substrate-dependent breast cancer resistance protein (Bcrp1/Abcg2)-mediated interactions: consideration of multiple binding sites in in vitro assay design

1 reference

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5 July 2018

Permeability--in vitro assays for assessing drug transporter activity

1 reference

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5 July 2018

Several major antiepileptic drugs are substrates for human P-glycoprotein

1 reference

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5 July 2018

Application and limitation of inhibitors in drug-transporter interactions studies

1 reference

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5 July 2018

In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system

1 reference

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5 July 2018

Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor

1 reference

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5 July 2018

Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein

1 reference

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5 July 2018

The role of the transporter P-glycoprotein for disposition and effects of centrally acting drugs and for the pathogenesis of CNS diseases

1 reference

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5 July 2018

Multidrug resistance-associated proteins 3, 4, and 5.

1 reference

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5 July 2018

Targeting multidrug resistance in cancer

1 reference

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5 July 2018

In vitro p-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: a recommendation for probe substrates.

1 reference

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5 July 2018

Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity

1 reference

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5 July 2018

Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938816

5 July 2018

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938816

5 July 2018

Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man.

1 reference

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5 July 2018

Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938816

5 July 2018

Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938816

5 July 2018

Mammalian ABC transporters in health and disease

1 reference

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5 July 2018

Comparison of furosemide and vinblastine secretion from cell lines overexpressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2).

1 reference

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5 July 2018

Rational use of in vitro P-glycoprotein assays in drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938816

5 July 2018

In vitro substrate identification studies for p-glycoprotein-mediated transport: species difference and predictability of in vivo results

1 reference

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5 July 2018

Multidrug-resistance transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938816

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Effect of multidrug resistance-reversing agents on transporting activity of human canalicular multispecific organic anion transporter

1 reference

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5 July 2018

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

1 reference

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P-glycoprotein is a dimer in the kidney and brain capillary membranes: effect of cyclosporin A and SDZ-PSC 833.

1 reference

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5 July 2018

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells

1 reference

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Transepithelial transport of drugs by the multidrug transporter in cultured Madin-Darby canine kidney cell epithelia

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5 July 2018

Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells

1 reference

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5 July 2018

Transfection of nonmuscle beta- and gamma-actin genes into myoblasts elicits different feedback regulatory responses from endogenous actin genes

1 reference

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5 July 2018

Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays

1 reference

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21 January 2018

Synergistic influence of Abcb1 and Abcc2 on disposition and sterol lowering effects of ezetimibe in rats.

1 reference

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21 January 2018

Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery

1 reference

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21 January 2018

Characterization of polarized expression of point- or deletion-mutated human BCRP/ABCG2 in LLC-PK1 cells.

1 reference

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21 January 2018

Guide to Receptors and Channels (GRAC), 4th Edition

1 reference

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Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

1 reference

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28 October 2018

Identifiers

10.1111/J.1476-5381.2010.00801.X

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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