(Q34141402)

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Telomerase inhibitors

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scholarly article

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

Telomerase inhibitors. (English)

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Europe PubMed Central

31 July 2017

Woodring E. Wright

2

object named as

Wright WE

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Europe PubMed Central

31 July 2017

author name string

White LK

1

1 reference

Europe PubMed Central

31 July 2017

Shay JW

3

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Europe PubMed Central

31 July 2017

publication date

1 March 2001

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Europe PubMed Central

31 July 2017

Trends in Biotechnology

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Europe PubMed Central

31 July 2017

19

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Europe PubMed Central

31 July 2017

114-120

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Europe PubMed Central

31 July 2017

3

1 reference

Europe PubMed Central

31 July 2017

Hayflick, his limit, and cellular ageing.

1 reference

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A role for both RB and p53 in the regulation of human cellular senescence

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The two-stage mechanism controlling cellular senescence and immortalization

1 reference

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Specific association of human telomerase activity with immortal cells and cancer

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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

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The RNA component of human telomerase

1 reference

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Telomere elongation in immortal human cells without detectable telomerase activity

1 reference

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Mice without telomerase: what can they teach us about human cancer?

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Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology

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Antisense oligonucleotides as therapeutic agents

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Inhibition of telomerase activity of melanoma cells in vitro by antisense oligonucleotides.

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Inhibition of human telomerase by a retrovirus expressing telomeric antisense RNA.

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A hexameric phosphorothioate oligonucleotide telomerase inhibitor arrests growth of Burkitt's lymphoma cells in vitro and in vivo.

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Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA.

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2-5A antisense directed against telomerase RNA produces apoptosis in ovarian cancer cells

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Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component.

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Inhibition of human telomerase activity by peptide nucleic acids.

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Telomerase inhibition by peptide nucleic acids reverses 'immortality' of transformed human cells

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Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

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Inhibition of Telomerase Activity by a Hammerhead Ribozyme Targeting the RNA Component of Telomerase in Human Melanoma Cells

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Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

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Inhibition of telomerase limits the growth of human cancer cells.

1 reference

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Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines

1 reference

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Inhibition of telomerase activity and cell proliferation by a reverse transcriptase inhibitor in gynaecological cancer cell lines

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Irreversible telomere shortening by 3'-azido-2',3'-dideoxythymidine (AZT) treatment

1 reference

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The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes

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Cytotoxic T cell immunity against telomerase reverse transcriptase in humans

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Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

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Human telomerase inhibition by substituted acridine derivatives

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Inhibition of human telomerase by a G-quadruplex-interactive compound

1 reference

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2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase

1 reference

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Molecular modeling studies on G-quadruplex complexes of telomerase inhibitors: structure-activity relationships

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Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

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10.1016/S0167-7799(00)01541-9

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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