(Q34147129)

31 July 2017

title

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy (English)

1 reference

31 July 2017

main subject

cognitive dysfunction

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inferred from title

author

Andreas Meyer-Lindenberg

18

1 reference

31 July 2017

2

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Bruno Dubois

11

Bruno Dubois

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Edward T. Bullmore

4

Edward T Bullmore

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Thérèse M Jay

Thérèse M Jay

15

1 reference

ORCID Public Data File 2021

Philip Gorwood

Philip Gorwood

14

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Robert J. DeRubeis

Robert J DeRubeis

10

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Michael Spedding

Michael Spedding

22

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Nicola Clayton

Nicola S Clayton

6

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Bill Deakin

Bill Deakin

9

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Edmund Rolls

Edmund Rolls

20

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Declan Murphy

Declan Murphy

19

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Martin Brüne

Martin Brüne

3

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Guy M. Goodwin

13

Guy M Goodwin

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31 July 2017

Mark J Millan

1

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31 July 2017

Cameron S Carter

5

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31 July 2017

Richard Connor

7

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31 July 2017

Sabrina Davis

8

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31 July 2017

Mark A Geyer

12

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31 July 2017

Marian Joëls

16

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31 July 2017

Isabelle M Mansuy

17

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31 July 2017

Bernd Saletu

21

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31 July 2017

John Sweeney

23

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31 July 2017

Miles Whittington

24

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31 July 2017

Larry J Young

25

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31 July 2017

publication date

1 February 2012

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Nature Reviews Drug Discovery

31 July 2017

published in

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31 July 2017

volume

11

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31 July 2017

issue

2

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31 July 2017

page(s)

141-168

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https://scigraph.springernature.com/pub.10.1038/nrd3628

31 July 2017

exact match

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Altered corticostriatal functional connectivity in obsessive-compulsive disorder

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Enhanced resting-state connectivity of amygdala in the immediate aftermath of acute psychological stress.

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Reversing neurodevelopmental disorders in adults

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Vulnerability genes or plasticity genes?

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Systems genetics for drug target discovery

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Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA.

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Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1.

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Removing obstacles in neuroscience drug discovery: the future path for animal models

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Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia

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Neurocognitive endophenotypes (endophenocognitypes) from studies of relatives of bipolar disorder subjects: a systematic review.

31 March 2020

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Effects of a genome-wide supported psychosis risk variant on neural activation during a theory-of-mind task.

31 March 2020

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Neurobehavioral Abnormalities in First-Degree Relatives of Individuals With Autism

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Endophenotypes of obsessive-compulsive disorder: rationale, evidence and future potential.

31 March 2020

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Treatment of cognitive deficits associated with schizophrenia: potential role of catechol-O-methyltransferase inhibitors

31 March 2020

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Tolcapone effects on gating, working memory, and mood interact with the synonymous catechol-O-methyltransferase rs4818c/g polymorphism.

31 March 2020

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Prefrontal-hippocampal coupling during memory processing is modulated by COMT val158met genotype.

31 March 2020

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Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition

31 March 2020

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Cognitive state and connectivity effects of the genome-wide significant psychosis variant in ZNF804A.

31 March 2020

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The impact of a genome-wide supported psychosis variant in the ZNF804A gene on memory function in schizophrenia.

31 March 2020

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22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia

31 March 2020

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Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia

31 March 2020

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The neuro-symphony of stress

31 March 2020

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Effects of stress throughout the lifespan on the brain, behaviour and cognition

31 March 2020

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Forebrain CRF₁ modulates early-life stress-programmed cognitive deficits

31 March 2020

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Memory formation under stress: quantity and quality

31 March 2020

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Synaptic plasticity in learning and memory: stress effects in the hippocampus.

31 March 2020

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Protection of stress-induced impairment of hippocampal/prefrontal LTP through blockade of glucocorticoid receptors: implication of MEK signaling.

31 March 2020

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Glucocorticoids act on glutamatergic pathways to affect memory processes.

31 March 2020

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Stress and glucocorticoid footprints in the brain-the path from depression to Alzheimer's disease

31 March 2020

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Membrane mineralocorticoid but not glucocorticoid receptors of the dorsal hippocampus mediate the rapid effects of corticosterone on memory retrieval

31 March 2020

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The prefrontal cortex as a key target of the maladaptive response to stress.

31 March 2020

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Stress-induced prefrontal reorganization and executive dysfunction in rodents

31 March 2020

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Stress, memory and the amygdala

31 March 2020

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Early maternal deprivation affects dentate gyrus structure and emotional learning in adult female rats.

31 March 2020

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Maternal care and hippocampal plasticity: evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress.

31 March 2020

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Pharmacological strategies for enhancing cognition in schizophrenia.

31 March 2020

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Deconstructing memory in Drosophila

31 March 2020

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Molecular mechanisms of memory storage in Aplysia

31 March 2020

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Translating rodent behavioral repertoire to zebrafish (Danio rerio): relevance for stress research.

31 March 2020

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Comparative social cognition

31 March 2020

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Twitter evolution: converging mechanisms in birdsong and human speech

31 March 2020

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Drug targets for cognitive enhancement in neuropsychiatric disorders

31 March 2020

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Attention-modulating effects of cognitive enhancers

31 March 2020

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The use of cognitive enhancers in animal models of fear extinction

31 March 2020

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Cognitive neuroscience of sleep

31 March 2020

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Circadian clocks: genes, sleep, and cognition.

31 March 2020

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Interactions between age, stress and insulin on cognition: implications for Alzheimer's disease

31 March 2020

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Insights into the role of dopamine receptor systems in learning and memory

31 March 2020

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A randomized clinical trial of MK-0777 for the treatment of cognitive impairments in people with schizophrenia

31 March 2020

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Cholinergic receptor subtypes and their role in cognition, emotion, and vigilance control: an overview of preclinical and clinical findings

31 March 2020

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A role for the 5-HT(1A), 5-HT4 and 5-HT6 receptors in learning and memory

31 March 2020

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5-HT(6) receptor and cognition.

31 March 2020

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31 March 2020

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The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior

31 March 2020

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31 March 2020

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Atomoxetine: a review of its use in attention-deficit hyperactivity disorder in children and adolescents

31 March 2020

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Adrenergic pharmacology and cognition: focus on the prefrontal cortex

31 March 2020

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The role of alpha2-adrenergic agonists in attention-deficit/hyperactivity disorder

31 March 2020

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The effects of the glycine reuptake inhibitor R213129 on the central nervous system and on scopolamine-induced impairments in psychomotor and cognitive function in healthy subjects

31 March 2020

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Modafinil improves information processing speed and increases energetic resources for orientation of attention in narcoleptics: double-blind, placebo-controlled ERP studies with low-resolution brain electromagnetic tomography (LORETA).

31 March 2020

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Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus.

31 March 2020

1 reference

Bell-shaped D-serine actions on hippocampal long-term depression and spatial memory retrieval

31 March 2020

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Under the curve: critical issues for elucidating D1 receptor function in working memory

31 March 2020

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New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

31 March 2020

1 reference

Structural dynamics of dendritic spines in memory and cognition

31 March 2020

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Protein serine/threonine phosphatases in neuronal plasticity and disorders of learning and memory

31 March 2020

1 reference

Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist.

31 March 2020

1 reference

Noradrenergic modulation of cognitive function in rat medial prefrontal cortex as measured by attentional set shifting capability

31 March 2020

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RGS14 at the interface of hippocampal signaling and synaptic plasticity

31 March 2020

1 reference

The inhibitory GABA system as a therapeutic target for cognitive symptoms in schizophrenia: investigational agents in the pipeline

31 March 2020

1 reference

Mechanism-based approaches to treating fragile X

31 March 2020

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Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease

31 March 2020

1 reference

mTOR signaling: at the crossroads of plasticity, memory and disease

31 March 2020

1 reference

Epigenetic inheritance in mammals: evidence for the impact of adverse environmental effects

31 March 2020

1 reference

Epigenetic treatments for cognitive impairments

31 March 2020

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Histamine H3 antagonists for treatment of cognitive deficits in CNS diseases

31 March 2020

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A cog in cognition: how the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits

31 March 2020

1 reference

Selective phosphodiesterase inhibitors: a promising target for cognition enhancement.

31 March 2020

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Phosphodiesterase inhibitors as potential cognition enhancing agents

31 March 2020

1 reference

Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety

31 March 2020

1 reference

Pharmacology of protein kinase C activators: cognition-enhancing and antidementic therapeutics

31 March 2020

1 reference

Increased particulate phosphodiesterase 4 in the prefrontal cortex supports 5-HT4 receptor-induced improvement of object recognition memory in the rat.

31 March 2020

1 reference

Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling

31 March 2020

1 reference

Consolidation and reconsolidation of contextual fear memory requires mammalian target of rapamycin-dependent translation in the dorsal hippocampus

31 March 2020

1 reference

GSK3beta, a centre-staged kinase in neuropsychiatric disorders, modulates long term memory by inhibitory phosphorylation at serine-9.

31 March 2020

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Glycogen synthase kinase-3 inhibition is integral to long-term potentiation.

31 March 2020

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Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition

31 March 2020

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Control of the establishment of aversive memory by calcineurin and Zif268.

31 March 2020

1 reference

Stress, depression, and neuroplasticity: a convergence of mechanisms

31 March 2020

1 reference

Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus.

31 March 2020

1 reference

A computational theory of episodic memory formation in the hippocampus

31 March 2020

1 reference

The medial temporal lobe and the attributes of memory

31 March 2020

1 reference

Hippocampal neurogenesis as a target for the treatment of mental illness: a critical evaluation

31 March 2020

1 reference

The Arc of synaptic memory

31 March 2020

1 reference

TrkB signalling pathways in LTP and learning

31 March 2020

1 reference

Induction of fear extinction with hippocampal-infralimbic BDNF

31 March 2020

1 reference

Genomic imprinting effects on brain development and function

31 March 2020

1 reference

Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

31 March 2020

1 reference

Epigenetics and the environmental regulation of the genome and its function

31 March 2020

1 reference

Epigenetic GABAergic targets in schizophrenia and bipolar disorder

31 March 2020

1 reference

The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes

31 March 2020

1 reference

HDAC2 negatively regulates memory formation and synaptic plasticity.

31 March 2020

1 reference

Nuclear protein phosphatase-1: an epigenetic regulator of fear memory and amygdala long-term potentiation.

31 March 2020

1 reference

MicroRNAs in memory processing

31 March 2020

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A novel pathway regulates memory and plasticity via SIRT1 and miR-134

31 March 2020

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MicroRNAs in mental health: from biological underpinnings to potential therapies

31 March 2020

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MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction

31 March 2020

1 reference

Cognitive therapy versus medication for depression: treatment outcomes and neural mechanisms

31 March 2020

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Cognitive Remediation in Schizophrenia

31 March 2020

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Are we studying and treating schizophrenia correctly?

31 March 2020

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Glutamate receptors in extinction and extinction-based therapies for psychiatric illness

31 March 2020

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D-cycloserine facilitates socially reinforced learning in an animal model relevant to autism spectrum disorders

31 March 2020

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Characteristics of the MATRICS Consensus Cognitive Battery in a 29-site antipsychotic schizophrenia clinical trial

31 March 2020

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Cognitive neuroscience-based approaches to measuring and improving treatment effects on cognition in schizophrenia: the CNTRICS initiative

31 March 2020

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Cognitive performance and functional competence as predictors of community independence in schizophrenia

31 March 2020

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Validating measures of real-world outcome: the results of the VALERO expert survey and RAND panel

31 March 2020

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Oculomotor and neuropsychological effects of antipsychotic treatment for schizophrenia

31 March 2020

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Development of eye-movement control

31 March 2020

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Pharmacological treatment effects on eye movement control

31 March 2020

1 reference

Control of visual cortical signals by prefrontal dopamine

31 March 2020

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An fMRI study of visual attention and sensorimotor function before and after antipsychotic treatment in first-episode schizophrenia

31 March 2020

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Applied strategies towards EEG/MEG biomarker identification in clinical and cognitive research

31 March 2020

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Preattentional and attentional cognitive deficits as targets for treating schizophrenia

31 March 2020

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Prediction of psychosis by mismatch negativity

31 March 2020

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Glutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patients

31 March 2020

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The role of phase synchronization in memory processes

31 March 2020

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Multiple origins of the cortical γ rhythm

31 March 2020

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Intranasal oxytocin modulates EEG mu/alpha and beta rhythms during perception of biological motion.

31 March 2020

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Electrophysiological basis for the ability of olanzapine to improve verbal memory and functional outcome in patients with schizophrenia: a LORETA analysis of P300.

31 March 2020

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Using MRI to measure drug action: caveats and new directions.

31 March 2020

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A single 20 mg dose of the full D1 dopamine agonist dihydrexidine (DAR-0100) increases prefrontal perfusion in schizophrenia

31 March 2020

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Short-term effects of antipsychotic treatment on cerebral function in drug-naive first-episode schizophrenia revealed by "resting state" functional magnetic resonance imaging.

31 March 2020

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Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia

31 March 2020

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Oxytocin Modulates Amygdala, Insula, and Inferior Frontal Gyrus Responses to Infant Crying: A Randomized Controlled Trial

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Different amygdala subregions mediate valence-related and attentional effects of oxytocin in humans

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Default-mode brain dysfunction in mental disorders: A systematic review

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Treatment with olanzapine is associated with modulation of the default mode network in patients with Schizophrenia

31 March 2020

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Effects of an alpha 7-nicotinic agonist on default network activity in schizophrenia

31 March 2020

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Modafinil modulation of the default mode network

31 March 2020

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Proton magnetic resonance spectroscopy study of brain metabolite changes after antipsychotic treatment.

31 March 2020

1 reference

Glutamate as a marker of cognitive function in schizophrenia: a proton spectroscopic imaging study at 4 Tesla.

31 March 2020

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The effect of clozapine on regional cerebral blood flow and brain metabolite ratios in schizophrenia: relationship with treatment response.

31 March 2020

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Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain

31 March 2020

1 reference

The use of PET imaging in studying cognition, genetics and pharmacotherapeutic interventions in schizophrenia

31 March 2020

1 reference

Understanding others' actions and goals by mirror and mentalizing systems: A meta-analysis

31 March 2020

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The neurobiology of pair bonding

31 March 2020

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Humans have evolved specialized skills of social cognition: the cultural intelligence hypothesis

31 March 2020

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Relating schizotypy and personality to the phenomenology of creativity

31 March 2020

1 reference

Large brains and cognition: where do elephants fit in?

31 March 2020

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Human and animal cognition: continuity and discontinuity

31 March 2020

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Ultrasonic vocalizations: a tool for behavioural phenotyping of mouse models of neurodevelopmental disorders.

31 March 2020

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Scent marking behavior as an odorant communication in mice

31 March 2020

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The social role of touch in humans and primates: behavioural function and neurobiological mechanisms

31 March 2020

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The FDA-NIMH-MATRICS guidelines for clinical trial design of cognitive-enhancing drugs: what do we know 5 years later?

31 March 2020

1 reference

Rescue of hippocampal LTP and learning deficits in a rat model of psychosis by inhibition of glycine transporter-1 (GlyT1).

31 March 2020

1 reference

Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade

31 March 2020

1 reference

mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning

31 March 2020

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Causal role of the prefrontal cortex in top-down modulation of visual processing and working memory

31 March 2020

1 reference

Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

31 March 2020

1 reference

Neuropsychologic effects of neuromodulation techniques for treatment-resistant depression: a review

31 March 2020

1 reference

Quality assessment and comparison of evidence for electroconvulsive therapy and repetitive transcranial magnetic stimulation for schizophrenia: a systematic meta-review

31 March 2020

1 reference

A single session of rTMS over the left dorsolateral prefrontal cortex influences attentional control in depressed patients.

31 March 2020

1 reference

Potentiation of gamma oscillatory activity through repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex.

31 March 2020

1 reference

Effects of low frequency repetitive transcranial magnetic stimulation (rTMS) on gamma frequency oscillations and event-related potentials during processing of illusory figures in autism.

31 March 2020

1 reference

The savant syndrome: an extraordinary condition. A synopsis: past, present, future

31 March 2020

1 reference

Transcranial direct current stimulation over Broca's region improves phonemic and semantic fluency in healthy individuals.

31 March 2020

1 reference

The fear circuitry in panic disorder and its modulation by cognitive-behaviour therapy interventions

31 March 2020

1 reference

A meta-analysis of cognitive remediation for schizophrenia: methodology and effect sizes

31 March 2020

1 reference

Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and Cortex

31 March 2020

1 reference

The Parieto-Frontal Integration Theory (P-FIT) of intelligence: Converging neuroimaging evidence

31 March 2020

1 reference

The anatomy of memory: an interactive overview of the parahippocampal-hippocampal network

31 March 2020

1 reference

Cerebellum and nonmotor function

31 March 2020

1 reference

The anatomy of language: a review of 100 fMRI studies published in 2009.

31 March 2020

1 reference

Ventral and dorsal pathways for language

31 March 2020

1 reference

Face perception is mediated by a distributed cortical network.

31 March 2020

1 reference

31 March 2020

The mirror neuron system

1 reference

Broca's area in language, action, and music.

31 March 2020

1 reference

Fronto-cerebellar circuits and eye movement control: a diffusion imaging tractography study of human cortico-pontine projections

31 March 2020

1 reference

Language, cognition and the cerebellum: grappling with an enigma

31 March 2020

1 reference

Blockade of dopamine D₃ but not D₂ receptors reverses the novel object discrimination impairment produced by post-weaning social isolation: implications for schizophrenia and its treatment

31 March 2020

1 reference

Blockade of dopamine D(3) receptors in frontal cortex, but not in sub-cortical structures, enhances social recognition in rats: similar actions of D(1) receptor agonists, but not of D(2) antagonists

31 March 2020

1 reference

Discovery of histamine H3 antagonists for the treatment of cognitive disorders and Alzheimer's disease

31 March 2020

1 reference

Muscarinic agonists for the treatment of cognition in schizophrenia

31 March 2020

1 reference

D-Serine and a glycine transporter-1 inhibitor enhance social memory in rats

31 March 2020

1 reference

The Therapeutic Potential of D-Amino Acid Oxidase (DAAO) Inhibitors

31 March 2020

1 reference

Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice

31 March 2020

1 reference

Prevention of ketamine-induced working memory impairments by AMPA potentiators in a nonhuman primate model of cognitive dysfunction

31 March 2020

1 reference

Metabotropic glutamate receptor subtype 5 antagonism in learning and memory

31 March 2020

1 reference

Reversal of ketamine-induced working memory impairments by the GABAAalpha2/3 agonist TPA023.

31 March 2020

1 reference

Adenosine receptor antagonists for cognitive dysfunction: a review of animal studies

31 March 2020

2 references

31 March 2020

12 December 2020

Selective inactivation of adenosine A(2A) receptors in striatal neurons enhances working memory and reversal learning.

1 reference

New topics in vasopressin receptors and approach to novel drugs: role of the vasopressin receptor in psychological and cognitive functions

31 March 2020

1 reference

PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice

31 March 2020

1 reference

Microtubules, schizophrenia and cognitive behavior: preclinical development of davunetide (NAP) as a peptide-drug candidate

31 March 2020

1 reference

SLV330, a cannabinoid CB1 receptor antagonist, ameliorates deficits in the T-maze, object recognition and Social Recognition Tasks in rodents.

31 March 2020

1 reference

12 December 2020

Modafinil as an adjunctive treatment of sedation, negative symptoms, and cognition in schizophrenia: a critical review

1 reference

12 December 2020

Cognitive effects of muscarinic M1 functional agonists in non-human primates and clinical trials

1 reference

12 December 2020

The prairie vole: an emerging model organism for understanding the social brain

1 reference

12 December 2020

A simple role for BDNF in learning and memory?

1 reference

12 December 2020

Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures

1 reference

12 December 2020

The cognitive functions of language

1 reference

12 December 2020

Treatment with valproic acid ameliorates ADHD symptoms in fragile X syndrome boys

1 reference

12 December 2020

Enhancing memory in late-life depression: the effects of a combined psychoeducation and cognitive training program.

1 reference

12 December 2020

Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS.

1 reference

12 December 2020

Neuronal network pharmacodynamics of GABAergic modulation in the human cortex determined using pharmaco-magnetoencephalography

1 reference

12 December 2020

The contribution of active medication to combined treatments of psychotherapy and pharmacotherapy for adult depression: a meta-analysis.

1 reference

12 December 2020

Functional atlas of emotional faces processing: a voxel-based meta-analysis of 105 functional magnetic resonance imaging studies

1 reference

12 December 2020

Cognitive impairment in schizophrenia: a review of developmental and genetic models, and pro-cognitive profile of the optimised D(3) > D(2) antagonist, S33138.

1 reference

12 December 2020

AMPA receptor potentiators as cognitive enhancers

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRD3628

1 reference

31 July 2017

1 reference