(Q34185658)

English

Inhibition of the intrinsic but not the extrinsic apoptosis pathway accelerates and drives MYC-driven tumorigenesis towards acute myeloid leukemia

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Inhibition of the intrinsic but not the extrinsic apoptosis pathway accelerates and drives MYC-driven tumorigenesis towards acute myeloid leukemia (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

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inferred from title

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Alf Grandien

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4

object named as

Björn Rozell

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Kari Högstrand

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Eduar Hejll

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Birgitta Sander

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Lars-Gunnar Larsson

5

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Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

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publication date

29 February 2012

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Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

e31366

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

copyright license

Creative Commons Attribution 4.0 International

29 February 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

MYC-induced myeloid leukemogenesis is accelerated by all six members of the antiapoptotic BCL family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Reflecting on 25 years with MYC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Apoptotic signaling by c-MYC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Molecular characterization of acute myeloid leukemia and its impact on treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Deregulation of apoptosis in acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

The Oscar-worthy role of Myc in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

MYC levels govern hematopoietic tumor type and latency in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Simultaneous expression and detection of multiple retroviral constructs in haematopoietic cells after bone marrow transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

The caspase-8 modulator c-FLIP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Bim is a suppressor of Myc-induced mouse B cell leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Myc pathways provoking cell suicide and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Focus on acute leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Deregulated c-Myc prematurely recruits both Type I and II CD95/Fas apoptotic pathways associated with terminal myeloid differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

A central role for death receptor-mediated apoptosis in the rejection of tumors by NK cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Characterization of the human FLICE-inhibitory protein locus and comparison of the anti-apoptotic activity of four different flip isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Reversible tumorigenesis by MYC in hematopoietic lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

The treatment of acute non-lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Differing patterns of proto-oncogene expression in immature and mature myeloid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Both myeloproliferative disease and leukemia are induced by transplantation of bone marrow cells expressing v-myc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

5 July 2018

Fatal acute lymphoblastic leukemia in mice transgenic for B cell-restricted bcl-xL and c-myc.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031366

21 January 2018

Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031366

21 January 2018

V-myc in a simple, single gene retroviral vector causes rapid induction of leukemia and concomitant apoptosis following bone marrow transplantation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031366

21 January 2018

Fas-independent apoptosis in T-cell tumours induced by the CD2-myc transgene

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031366

21 January 2018

T-cell lymphomas mask slower developing B-lymphoid and myeloid tumours in transgenic mice with broad haemopoietic expression of MYC

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031366

21 January 2018

MLL-ENL causes a reversible and myc-dependent block of myelomonocytic cell differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

28 October 2018

Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

28 October 2018

Survival and death of prelymphomatous B-cells from N-myc/bcl-2 double transgenic mice correlates with the regulation of intracellular Ca2+ fluxes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290626

28 October 2018

A matter of life and death

1 reference

https://pubmed.ncbi.nlm.nih.gov/22393362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of Fas/Apo-1 receptor accelerates lymphomagenesis in E mu L-MYC transgenic mice but not in animals infected with MoMuLV

1 reference

https://pubmed.ncbi.nlm.nih.gov/22393362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Participation of FLIP, RIP and Bcl-xLin Fas-mediated T-cell Death

1 reference

https://pubmed.ncbi.nlm.nih.gov/22393362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of N-Myc rapidly causes acute myeloid leukemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22393362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://pubmed.ncbi.nlm.nih.gov/22393362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0031366

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2012PLoSO...731366H

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1 reference

https://api.fatcat.wiki/v0/release/ormvvo4dpfdp7jz76ihfxt5yum

24 November 2022

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mapped directly with Wikidata item

PMC publication ID

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Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

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Europe PubMed Central

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31 July 2017

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