(Q34207138)

25151135

31 July 2017

title

A microbial biomanufacturing platform for natural and semisynthetic opioids (English)

1 reference

31 July 2017

0 references

Kate Thodey

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151135%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

publication date

24 August 2014

1 reference

25151135

31 July 2017

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151135%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151135%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151135%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

837-844

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151135%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4167936/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nchembio.1613

0 references

cites work

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Dioxygenases catalyze O-demethylation and O,O-demethylenation with widespread roles in benzylisoquinoline alkaloid metabolism in opium poppy

5 July 2018

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Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols.

5 July 2018

1 reference

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Benzylisoquinoline alkaloid metabolism: a century of discovery and a brave new world

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

5 July 2018

1 reference

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Organization of intracellular reactions with rationally designed RNA assemblies

5 July 2018

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A bacterial platform for fermentative production of plant alkaloids

5 July 2018

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Synthesis of morphine alkaloids and derivatives

5 July 2018

1 reference

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Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli

5 July 2018

1 reference

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Synthetic protein scaffolds provide modular control over metabolic flux.

5 July 2018

1 reference

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Synthesis of methyl halides from biomass using engineered microbes

5 July 2018

1 reference

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Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae

5 July 2018

1 reference

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Microbial production of plant benzylisoquinoline alkaloids

5 July 2018

1 reference

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A suite of Gateway cloning vectors for high-throughput genetic analysis in Saccharomyces cerevisiae

5 July 2018

1 reference

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Production of the antimalarial drug precursor artemisinic acid in engineered yeast

5 July 2018

1 reference

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Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

Electrospray tandem mass spectrometric investigations of morphinans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast

5 July 2018

1 reference

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Biological production of semisynthetic opiates using genetically engineered bacteria

5 July 2018

1 reference

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A new efficient gene disruption cassette for repeated use in budding yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

Purification and characterization of morphinone reductase from Pseudomonas putida M10.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

Saccharomyces cerevisiae CNE1 encodes an endoplasmic reticulum (ER) membrane protein with sequence similarity to calnexin and calreticulin and functions as a constituent of the ER quality control apparatus.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

Purification and Properties of Codeinone Reductase (NADPH) from Papaver somniferum Cell Cultures and Differentiated Plants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

Microbial degradation of the morphine alkaloids. Purification and characterization of morphine dehydrogenase from Pseudomonas putida M10.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167936

Systematic knockdown of morphine pathway enzymes in opium poppy using virus-induced gene silencing

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

Metabolic engineering of Saccharomyces cerevisiae for the synthesis of the wine-related antioxidant resveratrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

Improvement of reticuline productivity from dopamine by using engineered Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

Bench-top fermentative production of plant benzylisoquinoline alkaloids using a bacterial platform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

Berberine bridge enzyme, a key branch-point enzyme in benzylisoquinoline alkaloid biosynthesis, contains a vacuolar sorting determinant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

11 beta-hydroxylase activity in recombinant yeast mitochondria. In vivo conversion of 11-deoxycortisol to hydrocortisone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

Molecular cloning and functional expression of codeinone reductase: the penultimate enzyme in morphine biosynthesis in the opium poppy Papaver somniferum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

14-Hydroxylation of opiates: catalytic direct autoxidation of codeinone to 14-hydroxycodeinone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

Transformations of codeine to important semisynthetic opiate derivatives by Pseudomonas putida m10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

The GC-MS detection and characterization of neopine resulting from opium use and codeine metabolism and its potential as an opiate-product-use marker.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

Targeted metabolite and transcript profiling for elucidating enzyme function: isolation of novel N-methyltransferases from three benzylisoquinoline alkaloid-producing species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

Microbial degradation of the morphine alkaloids: identification of morphine as an intermediate in the metabolism of morphine by Pseudomonas putida M10

21 January 2018

1 reference

12 December 2020

Oripavine - a new opium alkaloid

1 reference

12 December 2020

Harnessing yeast subcellular compartments for the production of plant terpenoids

1 reference

12 December 2020

Isolation and purification of neopine

1 reference

12 December 2020

Biosynthetic conversion of thebaine to codeine

1 reference

12 December 2020

Increasing morphinan alkaloid production by over-expressing codeinone reductase in transgenic Papaver somniferum

1 reference

12 December 2020

De novo formation of transitional ER sites and Golgi structures in Pichia pastoris

1 reference

12 December 2020

The transformation of neopinone to codeinone in morphine biosynthesis proceeds non-enzymatically

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1613

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCHEMBIO.1613

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151135%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151135%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

25151135

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151135%20AND%20SRC:MED&resulttype=core&format=json