(Q34211942)

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PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Crohn's disease

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ulcerative colitis

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based on heuristic

inferred from title

genetic disease

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based on heuristic

inferred from title

15

object named as

Darina Czamara

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author name string

Jürgen Glas

1

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Europe PubMed Central

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31 July 2017

Johanna Wagner

2

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31 July 2017

Julia Seiderer

3

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31 July 2017

Torsten Olszak

4

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31 July 2017

Martin Wetzke

5

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31 July 2017

Florian Beigel

6

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31 July 2017

Cornelia Tillack

7

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31 July 2017

Johannes Stallhofer

8

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31 July 2017

Matthias Friedrich

9

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31 July 2017

Christian Steib

10

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31 July 2017

Burkhard Göke

11

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31 July 2017

Thomas Ochsenkühn

12

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31 July 2017

Nazanin Karbalai

13

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31 July 2017

Julia Diegelmann

14

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31 July 2017

Stephan Brand

16

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31 July 2017

language of work or name

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publication date

21 March 2012

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31 July 2017

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Europe PubMed Central

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31 July 2017

7

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Europe PubMed Central

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31 July 2017

3

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Europe PubMed Central

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31 July 2017

e33682

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Europe PubMed Central

PubMed publication ID

31 July 2017

copyright license

Creative Commons Attribution 4.0 International

21 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease

1 reference

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5 July 2018

E4BP4: an unexpected player in the immune response

1 reference

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5 July 2018

Investigation of multiple susceptibility loci for inflammatory bowel disease in an Italian cohort of patients

1 reference

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CEACAM6 gene variants in inflammatory bowel disease

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NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity

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New IBD genetics: common pathways with other diseases.

1 reference

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5 July 2018

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease

1 reference

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5 July 2018

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

1 reference

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5 July 2018

The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants

1 reference

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5 July 2018

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

1 reference

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5 July 2018

The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1

1 reference

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5 July 2018

Differences in genetic background between active smokers, passive smokers, and non-smokers with Crohn's disease

1 reference

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5 July 2018

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

1 reference

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5 July 2018

MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA.

1 reference

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5 July 2018

Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase n2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310077

5 July 2018

PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis

1 reference

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5 July 2018

Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310077

5 July 2018

Shared and distinct genetic variants in type 1 diabetes and celiac disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310077

5 July 2018

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310077

5 July 2018

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310077

5 July 2018

Unravelling the pathogenesis of inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310077

5 July 2018

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310077

5 July 2018

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310077

5 July 2018

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310077

5 July 2018

A Nonsynonymous SNP in ATG16L1 Predisposes to Ileal Crohn’s Disease and Is Independent of CARD15 and IBD5

1 reference

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Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

1 reference

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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

1 reference

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A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

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5 July 2018

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

1 reference

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

1 reference

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PTP1B and TC-PTP: novel roles in immune-cell signaling

1 reference

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Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

1 reference

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Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP

1 reference

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Inflammatory Bowel Disease

1 reference

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Identification of a nuclear Stat1 protein tyrosine phosphatase

1 reference

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Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase

1 reference

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1 reference

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The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

1 reference

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Regulation of interleukin 12 p40 expression through an NF-kappa B half-site

1 reference

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Classification of inflammatory bowel disease

1 reference

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5 July 2018

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033682

21 January 2018

Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033682

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Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study.

1 reference

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21 January 2018

Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease

1 reference

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Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort

1 reference

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Protein tyrosine phosphatase N2 regulates TNFα-induced signalling and cytokine secretion in human intestinal epithelial cells.

1 reference

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21 January 2018

Crohn's disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310077

28 October 2018

PTPN2 but not PTPN22 is associated with Crohn's disease in a New Zealand population

1 reference

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Protein tyrosine phosphatase nonreceptor type 2 regulates autophagosome formation in human intestinal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22457781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of tyrosine phosphatases that dephosphorylate the insulin receptor. A brute force approach based on "substrate-trapping" mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/22457781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22457781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TheATG16L1Gene Variants rs2241879 and rs2241880 (T300A) Are Strongly Associated With Susceptibility to Crohn's Disease in the German Population

1 reference

https://pubmed.ncbi.nlm.nih.gov/22457781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0033682

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2012PLoSO...733682G

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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