(Q34213669)

31 July 2017

title

Small amphipathic molecules modulate secondary structure and amyloid fibril-forming kinetics of Alzheimer disease peptide Aβ(1-42). (English)

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31 July 2017

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5

Colin Masters

1 reference

31 July 2017

Timothy M Ryan

1

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31 July 2017

Anna Friedhuber

2

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31 July 2017

Monica Lind

3

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31 July 2017

Geoffrey J Howlett

4

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31 July 2017

Blaine R Roberts

6

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31 July 2017

language of work or name

English

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publication date

29 March 2012

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Journal of Biological Chemistry

31 July 2017

published in

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31 July 2017

volume

287

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31 July 2017

issue

20

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31 July 2017

page(s)

16947-16954

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Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Design of small molecules that target metal-A{beta} species and regulate metal-induced A{beta} aggregation and neurotoxicity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Phospholipids enhance nucleation but not elongation of apolipoprotein C-II amyloid fibrils

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Enrichment of cholesterol in microdissected Alzheimer's disease senile plaques as assessed by mass spectrometry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

The Caenorhabditis elegans A beta 1-42 model of Alzheimer disease predominantly expresses A beta 3-42.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Alpha-helix targeting reduces amyloid-beta peptide toxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Fluorescence detection of a lipid-induced tetrameric intermediate in amyloid fibril formation by apolipoprotein C-II.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Animal models of Alzheimer's disease and frontotemporal dementia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Localization of the noncovalent binding site between amyloid-beta-peptide and oleuropein using electrospray ionization FT-ICR mass spectrometry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Formation of native prions from minimal components in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Molecular understanding of Abeta peptide interaction with isoflurane, propofol, and thiopental: NMR spectroscopic study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Lipid-induced beta-amyloid peptide assemblage fragmentation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

alphaB-crystallin competes with Alzheimer's disease beta-amyloid peptide for peptide-peptide interactions and induces oxidation of Abeta-Met35

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

An alternative interpretation of the amyloid Abeta hypothesis with regard to the pathogenesis of Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Part of membrane-bound Abeta exists in rafts within senile plaques in Tg2576 mouse brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

On the analysis of protein self-association by sedimentation velocity analytical ultracentrifugation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Amyloid beta-protein interactions with membranes and cholesterol: causes or casualties of Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AbetaP (1-40) and (1-42) peptides.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Cholesterol, a modulator of membrane-associated Abeta-fibrillogenesis and neurotoxicity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Selective inhibition of Abeta fibril formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Amyloid fibril toxicity in Alzheimer's disease and diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Epidemiology of Alzheimer's Disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351313

Amyloid-beta membrane binding and permeabilization are distinct processes influenced separately by membrane charge and fluidity

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Non-electrostatic binding and self-association of amyloid beta-peptide on the surface of tightly packed phosphatidylcholine membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Driving force of binding of amyloid beta-protein to lipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Conformational switching and fibrillogenesis in the amyloidogenic fragment of apolipoprotein a-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Alpha-synuclein selectively binds to anionic phospholipids embedded in liquid-disordered domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Phospholipid catalysis of diabetic amyloid assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Mechanism of lysophosphatidic acid-induced amyloid fibril formation of beta(2)-microglobulin in vitro under physiological conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Two types of Alzheimer's beta-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Effect of cholesterol and amyloid-β peptide on structure and function of mixed-lipid films and pulmonary surfactant BLES: an atomic force microscopy study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Fatty acids increase presenilin-1 levels and [gamma]-secretase activity in PSwt-1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Study of the interaction between the amyloid beta peptide (1-40) and antioxidant compounds by nuclear magnetic resonance spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Alzheimer's disease: halothane induces Abeta peptide to oligomeric form--solution NMR studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Alzheimer's disease: NMR studies of asialo (GM1) and trisialo (GT1b) ganglioside interactions with Abeta(1-40) peptide in a membrane mimic environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

Ganglioside GM1-Mediated Amyloid-beta Fibrillogenesis and Membrane Disruption†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.321778

High-affinity amphipathic modulators of amyloid fibril nucleation and elongation

21 January 2018

1 reference

12 December 2020

Negatively charged phospholipid membranes induce amyloid formation of medin via an alpha-helical intermediate

1 reference

12 December 2020

The genetics of Alzheimer's disease

1 reference

12 December 2020

Lipid binding to amyloid beta-peptide aggregates: preferential binding of cholesterol as compared with phosphatidylcholine and fatty acids

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.321778

1 reference

31 July 2017

1 reference

31 July 2017

1 reference