(Q33879010)

29 July 2017

An alternative interpretation of the amyloid Abeta hypothesis with regard to the pathogenesis of Alzheimer's disease (English)

1 reference

29 July 2017

0 references

Vincent T Marchesi

1

1 reference

PubMed ID

15967987

29 July 2017

language of work or name

English

0 references

publication date

20 June 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

29 July 2017

102

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29 July 2017

26

1 reference

29 July 2017

9093-9098

1 reference

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Aph-1 contributes to the stabilization and trafficking of the gamma-secretase complex through mechanisms involving intermolecular and intramolecular interactions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Neuronal membrane cholesterol loss enhances amyloid peptide generation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Identification of a new presenilin-dependent zeta-cleavage site within the transmembrane domain of amyloid precursor protein.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Amyloid-beta precursor protein processing in neurodegeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Selected non-steroidal anti-inflammatory drugs and their derivatives target gamma-secretase at a novel site. Evidence for an allosteric mechanism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Modeling amyloid beta-peptide insertion into lipid bilayers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Transmembrane peptides as inhibitors of ErbB receptor signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Selection and characterization of small random transmembrane proteins that bind and activate the platelet-derived growth factor beta receptor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gamma-secretase complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Sequence motifs, polar interactions and conformational changes in helical membrane proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

The channel hypothesis of Alzheimer's disease: current status

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Intracellular amyloid-beta 1-42, but not extracellular soluble amyloid-beta peptides, induces neuronal apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Clearing the brain's amyloid cobwebs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Amino-acid sequence and oligosaccharide attachment sites of human erythrocyte glycophorin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Subunit structure of human erythrocyte glycophorin A

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503181102

Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503181102

Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503181102

In vivo detection of hetero-association of glycophorin-A and its mutants within the membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503181102

Complex interactions at the helix-helix interface stabilize the glycophorin A transmembrane dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503181102

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503181102

Transmembrane domain mediated self-assembly of major coat protein subunits from Ff bacteriophage

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503181102

Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503181102

A transmembrane segment mimic derived from Escherichia coli diacylglycerol kinase inhibits protein activity

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166615

The Affinity of GXXXG Motifs in Transmembrane Helix-Helix Interactions Is Modulated by Long-range Communication

29 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503181102

T-cell antigen receptor transmembrane peptides modulate T-cell function and T cell-mediated disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15967987

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Peptide mimics of the M13 coat protein transmembrane segment. Retention of helix-helix interaction motifs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15967987

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0503181102

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference

PubMed ID

15967987