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20 years of leptin: connecting leptin signaling to biological function
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Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
review article
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stated in
Europe PubMed Central
title
20 years of leptin: connecting leptin signaling to biological function
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
author
Margaret B Allison
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
author name string
Martin G Myers
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2
1 reference
stated in
Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
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16 February 2020
language of work or name
English
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publication date
1 October 2014
1 reference
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Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
published in
Journal of Endocrinology
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stated in
Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
volume
223
1 reference
stated in
Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
page(s)
T25-35
1 reference
stated in
Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
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Leptin: a potential novel antidepressant
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LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin
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Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
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28 July 2018
Modulation of direct leptin signaling by soluble leptin receptor
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28 July 2018
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
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Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.
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28 July 2018
PTP1B regulates leptin signal transduction in vivo
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28 July 2018
Intracellular signalling. Key enzyme in leptin-induced anorexia
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28 July 2018
SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985
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28 July 2018
Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice
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28 July 2018
Activation of downstream signals by the long form of the leptin receptor
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28 July 2018
Central nervous system control of food intake
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28 July 2018
The role of SOCS-3 in leptin signaling and leptin resistance
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28 July 2018
Effects of recombinant leptin therapy in a child with congenital leptin deficiency.
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28 July 2018
Leptin and the regulation of body weight in mammals
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28 July 2018
Identification of SOCS-3 as a potential mediator of central leptin resistance
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28 July 2018
Fine structure of the murine leptin receptor gene: splice site suppression is required to form two alternatively spliced transcripts
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28 July 2018
Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding
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PubMed Central
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28 July 2018
Congenital leptin deficiency is associated with severe early-onset obesity in humans
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28 July 2018
The leptin receptor
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28 July 2018
Leptin accelerates the onset of puberty in normal female mice
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28 July 2018
Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization
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28 July 2018
The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors
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28 July 2018
Abnormal splicing of the leptin receptor in diabetic mice
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28 July 2018
Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice
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28 July 2018
Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor
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28 July 2018
Identification and expression cloning of a leptin receptor, OB-R
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28 July 2018
Positional cloning of the mouse obese gene and its human homologue
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28 July 2018
Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity
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28 July 2018
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
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28 July 2018
Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action
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28 July 2018
Improved metabolic phenotype of hypothalamic PTP1B-deficiency is dependent upon the leptin receptor.
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PubMed Central
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28 October 2018
Neither signal transducer and activator of transcription 3 (STAT3) or STAT5 signaling pathways are required for leptin's effects on fertility in mice
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
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28 October 2018
Deficiency of PTP1B in leptin receptor-expressing neurons leads to decreased body weight and adiposity in mice.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Shp2 controls female body weight and energy balance by integrating leptin and estrogen signals.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
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28 October 2018
Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
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28 October 2018
Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
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28 October 2018
The soluble leptin receptor neutralizes leptin-mediated STAT3 signalling and anorexic responses in vivo
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
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28 October 2018
Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Activation of Stat3 signaling in AgRP neurons promotes locomotor activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Neuronal PTP1B regulates body weight, adiposity and leptin action.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Role of Signal Transducer and Activator of Transcription 3 in Regulation of Hypothalamic Proopiomelanocortin Gene Expression by Leptin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Regulation of Jak kinases by intracellular leptin receptor sequences.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Divergent roles of SHP-2 in ERK activation by leptin receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Expression of leptin receptor isoforms in rat brain microvessels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
The soluble leptin receptor is crucial for leptin action: evidence from clinical and experimental data
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170570
retrieved
28 October 2018
Decreased transport of leptin across the blood-brain barrier in rats lacking the short form of the leptin receptor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25232147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chemical characterization of leptin-activated neurons in the rat brain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25232147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Relationship between serum leptin and fatty liver in Japanese male adolescent university students
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25232147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1530/JOE-14-0404
1 reference
stated in
Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
PMCID
4170570
1 reference
stated in
Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
PubMed ID
25232147
1 reference
stated in
Europe PubMed Central
PMCID
4170570
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25232147%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
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