(Q34276818)

1 August 2017

title

Molecular imaging of microglia/macrophages in the brain (English)

1 reference

1 August 2017

0 references

1 reference

Sriram Venneti

1

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1 August 2017

Brian J Lopresti

series ordinal

2

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1 August 2017

Clayton A Wiley

series ordinal

3

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1 August 2017

language of work or name

1 reference

21 May 2012

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1 August 2017

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1 August 2017

volume

61

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1 August 2017

issue

1

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1 August 2017

page(s)

10-23

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Imaging brain microglial activation using positron emission tomography and translocator protein-specific radioligands

1 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Non-invasive imaging of the type 2 cannabinoid receptor, focus on positron emission tomography

6 July 2018

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6 July 2018

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6 July 2018

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D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model

6 July 2018

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Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker

6 July 2018

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Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia

6 July 2018

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Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects

6 July 2018

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Microglial physiology: unique stimuli, specialized responses

6 July 2018

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PET imaging of the peripheral benzodiazepine receptor: monitoring disease progression and therapy response in neurodegenerative disorders

6 July 2018

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Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies

6 July 2018

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Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers.

6 July 2018

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The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders

6 July 2018

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In vivo monitoring of inflammation after cardiac and cerebral ischemia by fluorine magnetic resonance imaging

6 July 2018

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Bone-marrow-derived microglia: myth or reality?

6 July 2018

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PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET.

6 July 2018

1 reference

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Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation

6 July 2018

1 reference

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The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds to activated and infected brain macrophages in areas of synaptic degeneration: implications for PET imaging of neuroinflammation in lentiviral encephalitis

6 July 2018

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Neurocognitive effects of methamphetamine: a critical review and meta-analysis

6 July 2018

1 reference

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The acute-phase protein alpha 1-acid glycoprotein (AGP) induces rises in cytosolic Ca2+ in neutrophil granulocytes via sialic acid binding immunoglobulin-like lectins (siglecs).

6 July 2018

1 reference

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The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: implications for PET imaging

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Consensus nomenclature for in vivo imaging of reversibly binding radioligands

6 July 2018

1 reference

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The acute phase protein alpha1-acid glycoprotein: a model for altered glycosylation during diseases

6 July 2018

1 reference

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Imaging inflammation in acute brain ischemia

6 July 2018

1 reference

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The origin and cell lineage of microglia: new concepts

6 July 2018

1 reference

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The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

In vivo evidence for microglial activation in neurodegenerative dementia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

In situ labeling of immune cells with iron oxide particles: an approach to detect organ rejection by cellular MRI.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Peripheral-type benzodiazepine receptor in neurosteroid biosynthesis, neuropathology and neurological disorders.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

ATP mediates rapid microglial response to local brain injury in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Determination of lipophilicity and its use as a predictor of blood-brain barrier penetration of molecular imaging agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability transition pore.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Mitochondrial apoptosis and the peripheral benzodiazepine receptor: a novel target for viral and pharmacological manipulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Visualising microglial activation in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Peripheral benzodiazepine receptors and mitochondrial function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Viruses and apoptosis: meddling with mitochondria

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Parametric imaging of ligand-receptor binding in PET using a simplified reference region model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Human microglia convert l-tryptophan into the neurotoxin quinolinic acid

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Interleukin 1 of the central nervous system is produced by ameboid microglia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Monokine production by microglial cell clones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

In vivo binding to peripheral benzodiazepine binding sites in lesioned rat brain: comparison between [3H]PK11195 and [18F]PK14105 as markers for neuronal damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Macrophage and astrocyte populations in relation to [3H]PK 11195 binding in rat cerebral cortex following a local ischaemic lesion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Brain kinetics and specific binding of [11C]PK 11195 to omega 3 sites in baboons: positron emission tomography study.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Peripheral-type benzodiazepine receptors in human cerebral cortex, kidney, and colon

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

The distribution of radioactivity in brains of rats given [N-methyl-11C]PK 11195 in vivo after induction of a cortical ischaemic lesion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Activated microglia mediate neuronal cell injury via a nitric oxide mechanism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

High densities of benzodiazepine receptors in human cortical areas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

A systematic comparison of kinetic modelling methods generating parametric maps for [(11)C]-(R)-PK11195.

6 July 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

In-vivo measurement of activated microglia in dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Evaluation of [11C]-DAA1106 for imaging and quantification of neuroinflammation in a rat model of herpes encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Amphetamine pretreatment induces a change in both D2-Receptor density and apparent affinity: a [11C]raclopride positron emission tomography study in cats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Evaluation of reference tissue models for the analysis of [11C](R)-PK11195 studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Development of a tracer kinetic plasma input model for (R)-[11C]PK11195 brain studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Simplified reference tissue model for PET receptor studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

The peripheral benzodiazepine receptor ligand PK11195 binds with high affinity to the acute phase reactant alpha1-acid glycoprotein: implications for the use of the ligand as a CNS inflammatory marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

PET of glial metabolism using 2-18F-fluoroacetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

In vivo detection of neuropathologic changes in presymptomatic MAPT mutation carriers: a PET and MRI study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Up-regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Characterization of binding sites for the omega3 receptor ligands [3H]PK11195 and [3H]RO5-4864 in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Transient protection by peripheral benzodiazepine receptors during the early events of ultraviolet light-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Peripheral benzodiazepine receptors in patients with chronic schizophrenia: a PET study with [11C]DAA1106.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Increased binding of peripheral benzodiazepine receptor in Alzheimer's disease measured by positron emission tomography with [11C]DAA1106.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Glial cell-mediated deterioration and repair of the nervous system after traumatic brain injury in a rat model as assessed by positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22357

Reference and target region modeling of [11C]-(R)-PK11195 brain studies

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Mitochondrial benzodiazepine receptors mediate inhibition of mitochondrial respiratory control

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580157

Protease production by cultured microglia: substrate gel analysis and immobilized matrix degradation

28 October 2018

1 reference

12 December 2020

Cellular and subcellular localization of peripheral benzodiazepine receptors after trimethyltin neurotoxicity

1 reference

12 December 2020

Calculation of positron range and its effect on the fundamental limit of positron emission tomography system spatial resolution

1 reference

12 December 2020

Tumor necrosis factor-alpha production by human fetal microglial cells: regulation by other cytokines

1 reference

12 December 2020

Discussion of targeting proteins in vivo: in vitro guidelines

1 reference

12 December 2020

Peripheral-type benzodiazepine receptors in the living heart characterized by positron emission tomography

1 reference

12 December 2020

16 alpha-[77Br]bromo-11 beta-methoxyestradiol-17 beta: a gamma-emitting estrogen imaging agent with high uptake and retention by target organs

1 reference

12 December 2020

Decreases in peripheral-type benzodiazepine receptors in postmortem brains of chronic schizophrenics

1 reference

12 December 2020

Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat

1 reference

12 December 2020

Traumatic brain injury leads to increased expression of peripheral-type benzodiazepine receptors, neuronal death, and activation of astrocytes and microglia in rat thalamus

1 reference

12 December 2020

Topological analysis of the peripheral benzodiazepine receptor in yeast mitochondrial membranes supports a five-transmembrane structure

1 reference

12 December 2020

PK ('peripheral benzodiazepine')--binding sites in the CNS indicate early and discrete brain lesions: microautoradiographic detection of [3H]PK11195 binding to activated microglia

1 reference

12 December 2020

Modulation of human microglial cell superoxide production by cytokines

1 reference

12 December 2020

The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity

1 reference

12 December 2020

Identifiers

DOI

10.1002/GLIA.22357

1 reference

1 August 2017

1 reference

1 August 2017

1 reference