(Q37814088)

23 August 2017

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title

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders (English)

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23 August 2017

5

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Vasilios Papadopoulos

2

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Michael Schumacher

object named as

Michael Schumacher

9

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Gerhard Rammes

3

object named as

Gerhard Rammes

1 reference

23 August 2017

Rainer Rupprecht

1

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23 August 2017

Thomas C Baghai

4

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23 August 2017

Nagaraju Akula

6

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23 August 2017

Ghislaine Groyer

7

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23 August 2017

David Adams

8

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23 August 2017

publication date

1 December 2010

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Nature Reviews Drug Discovery

23 August 2017

published in

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23 August 2017

volume

9

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23 August 2017

issue

12

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23 August 2017

page(s)

971-988

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Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

23 August 2017

cites work

1 reference

Is there a mitochondrial signaling complex facilitating cholesterol import?

31 March 2020

1 reference

Evidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis

31 March 2020

1 reference

Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells

31 March 2020

1 reference

In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding.

31 March 2020

1 reference

Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis

31 March 2020

1 reference

Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair

31 March 2020

1 reference

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers.

31 March 2020

1 reference

Quantitative analysis of peripheral benzodiazepine receptor in the human brain using PET with (11)C-AC-5216.

31 March 2020

1 reference

Etifoxine improves peripheral nerve regeneration and functional recovery

31 March 2020

1 reference

Anxiolytic-like effects of N,N-dialkyl-2-phenylindol-3-ylglyoxylamides by modulation of translocator protein promoting neurosteroid biosynthesis

31 March 2020

1 reference

Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects

31 March 2020

1 reference

Topological analysis of the peripheral benzodiazepine receptor in yeast mitochondrial membranes supports a five-transmembrane structure

31 March 2020

1 reference

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

31 March 2020

1 reference

VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis

31 March 2020

1 reference

In vitro studies on the role of the peripheral-type benzodiazepine receptor in steroidogenesis

31 March 2020

1 reference

Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis

31 March 2020

1 reference

Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states.

31 March 2020

1 reference

Translocator protein 2 is involved in cholesterol redistribution during erythropoiesis

31 March 2020

1 reference

Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis

31 March 2020

1 reference

Peripheral benzodiazepine receptors and mitochondrial function

31 March 2020

1 reference

Cellular and subcellular localization of peripheral benzodiazepine receptors after trimethyltin neurotoxicity

31 March 2020

1 reference

Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor

31 March 2020

1 reference

Peripheral-type benzodiazepine receptors in the central nervous system: localization to olfactory nerves

31 March 2020

1 reference

Differential regulation of ‘central’ and ‘peripheral’ benzodiazepine binding sites in the rat olfactory bulb

31 March 2020

1 reference

Axonal injury-dependent induction of the peripheral benzodiazepine receptor in small-diameter adult rat primary sensory neurons

31 March 2020

1 reference

Peripheral benzodiazepine receptor (PBR) new insight in cell proliferation and cell differentiation review.

31 March 2020

1 reference

Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response

31 March 2020

1 reference

Effects of peripheral-type benzodiazepine receptor antisense knockout on MA-10 Leydig cell proliferation and steroidogenesis

31 March 2020

1 reference

The peripheral-type benzodiazepine receptor and tumorigenicity: isoquinoline binding protein (IBP) antisense knockdown in the C6 glioma cell line

31 March 2020

1 reference

Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria

31 March 2020

1 reference

Peripheral-type benzodiazepine receptor (PBR) and PBR drug ligands in fibroblast and fibrosarcoma cell proliferation: role of ERK, c-Jun and ligand-activated PBR-independent pathways

31 March 2020

1 reference

Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation

31 March 2020

1 reference

CoCl(2) induces apoptosis via the 18 kDa translocator protein in U118MG human glioblastoma cells

31 March 2020

1 reference

Mitochondrial function in Leydig cell steroidogenesis

31 March 2020

1 reference

A 3D model of the peripheral benzodiazepine receptor and its implication in intra mitochondrial cholesterol transport

31 March 2020

1 reference

Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern

31 March 2020

1 reference

Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide

31 March 2020

1 reference

Characterization of the cholesterol recognition amino acid consensus sequence of the peripheral-type benzodiazepine receptor

31 March 2020

1 reference

Structural and functional study of reconstituted peripheral benzodiazepine receptor

31 March 2020

1 reference

Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding

31 March 2020

1 reference

Three-dimensional structure of TspO by electron cryomicroscopy of helical crystals

31 March 2020

1 reference

Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation

31 March 2020

1 reference

Role of the peripheral benzodiazepine receptor in sensory neuron regeneration

31 March 2020

1 reference

Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury

31 March 2020

1 reference

Chronic neuropathic pain is accompanied by global changes in gene expression and shares pathobiology with neurodegenerative diseases

31 March 2020

1 reference

Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain.

31 March 2020

1 reference

Visualising microglial activation in vivo

31 March 2020

1 reference

Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization

31 March 2020

1 reference

Evolution of microglial activation in patients after ischemic stroke: a [11C](R)-PK11195 PET study

31 March 2020

1 reference

Pathophysiology of ischaemic stroke: insights from imaging, and implications for therapy and drug discovery.

31 March 2020

1 reference

The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: implications for PET imaging

31 March 2020

1 reference

Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma

31 March 2020

1 reference

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

31 March 2020

1 reference

Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

31 March 2020

1 reference

Increased binding of peripheral benzodiazepine receptor in Alzheimer's disease measured by positron emission tomography with [11C]DAA1106.

31 March 2020

1 reference

Peripheral-type benzodiazepine receptor in neurosteroid biosynthesis, neuropathology and neurological disorders.

31 March 2020

1 reference

In vivo detection of microglial activation in frontotemporal dementia

31 March 2020

1 reference

Microglial imaging with positron emission tomography and atrophy measurements with magnetic resonance imaging in multiple sclerosis: a correlative study.

31 March 2020

1 reference

Microglial activation correlates with severity in Huntington disease: a clinical and PET study.

31 March 2020

1 reference

Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study.

31 March 2020

1 reference

Microglial activation and dopamine terminal loss in early Parkinson's disease

31 March 2020

1 reference

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

31 March 2020

1 reference

Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies

31 March 2020

1 reference

Increased peripheral benzodiazepine binding sites and pentraxin 3 expression in the spinal cord during EAE: relation to inflammatory cytokines and modulation by dexamethasone and rolipram

31 March 2020

1 reference

Immunohistochemical expression of peripheral benzodiazepine receptors in human astrocytomas and its correlation with grade of malignancy, proliferation, apoptosis and survival

31 March 2020

1 reference

A novel functional translocator protein ligand for cancer imaging

31 March 2020

1 reference

Economic evaluation of PET and PET/CT in oncology: evidence and methodologic approaches

31 March 2020

1 reference

Imaging of peripheral-type benzodiazepine receptor in tumor: in vitro binding and in vivo biodistribution of N-benzyl-N-[(11)C]methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide

31 March 2020

1 reference

Effects of antidepressant treatment on neuroactive steroids in major depression

31 March 2020

1 reference

Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties

31 March 2020

1 reference

Induced panic attacks shift gamma-aminobutyric acid type A receptor modulatory neuroactive steroid composition in patients with panic disorder: preliminary results

31 March 2020

1 reference

Stress, anxiety and peripheral benzodiazepine receptor mRNA levels in human lymphocytes.

31 March 2020

1 reference

Peripheral benzodiazepine receptor messenger RNA is decreased in lymphocytes of generalized anxiety disorder patients

31 March 2020

1 reference

Platelet 18 kDa Translocator Protein density is reduced in depressed patients with adult separation anxiety

31 March 2020

1 reference

Altered platelet peripheral-type benzodiazepine receptor in posttraumatic stress disorder.

31 March 2020

1 reference

Abnormal peripheral benzodiazepine receptor density associated with generalized social phobia

31 March 2020

1 reference

Peripheral-type benzodiazepine receptors on platelets are correlated with the degrees of anxiety in normal human subjects.

31 March 2020

1 reference

Peripheral-type benzodiazepine receptor binding sites in platelets of patients with panic disorder associated to separation anxiety symptoms

31 March 2020

1 reference

Decreased platelet peripheral-type benzodiazepine receptors in persistently violent schizophrenia patients

31 March 2020

1 reference

Decreased platelet peripheral-type benzodiazepine receptors in adolescent inpatients with repeated suicide attempts.

31 March 2020

1 reference

Platelet peripheral-type benzodiazepine receptor in major depression

31 March 2020

1 reference

Reductions in Platelet 18-kDa Translocator Protein Density Are Associated with Adult Separation Anxiety in Patients with Bipolar Disorder

31 March 2020

1 reference

Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression

31 March 2020

1 reference

The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals

31 March 2020

1 reference

Evidence that variation in the peripheral benzodiazepine receptor (PBR) gene influences susceptibility to panic disorder

31 March 2020

1 reference

Peripheral benzodiazepine receptors in patients with chronic schizophrenia: a PET study with [11C]DAA1106.

31 March 2020

1 reference

Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptor

31 March 2020

1 reference

Diazepam binding inhibitor (DBI): a peptide with multiple biological actions

31 March 2020

1 reference

Mapping and fitting the peripheral benzodiazepine receptor binding site by carboxamide derivatives. Comparison of different approaches to quantitative ligand-receptor interaction modeling

31 March 2020

1 reference

The Mr 18,000 subunit of the peripheral-type benzodiazepine receptor exhibits both benzodiazepine and isoquinoline carboxamide binding sites in the absence of the voltage-dependent anion channel or of the adenine nucleotide carrier

31 March 2020

1 reference

Pharmacological characterization of the receptor mediating the anorexigenic action of the octadecaneuropeptide: evidence for an endozepinergic tone regulating food intake

31 March 2020

1 reference

Diazepam Binding Inhibitor and Its Processing Products Stimulate Mitochondrial Steroid Biosynthesis via an Interaction with Mitochondrial Benzodiazepine Receptors*

31 March 2020

1 reference

Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA

31 March 2020

1 reference

Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): an emerging signaling molecule.

31 March 2020

1 reference

Modification of the peripheral-type benzodiazepine receptor by arachidonate, diethylpyrocarbonate and thiol reagents

31 March 2020

1 reference

Multiple contributions from long-chain fatty acid metabolism in Y-1 and MA-10 cells.

31 March 2020

1 reference

Beta-amyloid peptide stimulates endozepine release in cultured rat astrocytes through activation of N-formyl peptide receptors

31 March 2020

1 reference

Cerebrospinal fluid levels of diazepam-binding inhibitor in neurodegenerative disorders with dementia

31 March 2020

1 reference

The anxiolytic etifoxine activates the peripheral benzodiazepine receptor and increases the neurosteroid levels in rat brain

31 March 2020

1 reference

The modulatory effects of the anxiolytic etifoxine on GABA(A) receptors are mediated by the beta subunit

31 March 2020

1 reference

Modulation of GABAergic synaptic transmission by the non-benzodiazepine anxiolytic etifoxine.

31 March 2020

1 reference

Efficacy of etifoxine compared to lorazepam monotherapy in the treatment of patients with adjustment disorders with anxiety: a double-blind controlled study in general practice

31 March 2020

1 reference

SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repair

31 March 2020

1 reference

Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy-induced neuropathy

31 March 2020

1 reference

Neuroprotective effects of a ligand of translocator protein-18 kDa (Ro5-4864) in experimental diabetic neuropathy.

31 March 2020

1 reference

Reduction and prevention of vincristine-induced neuropathic pain symptoms by the non-benzodiazepine anxiolytic etifoxine are mediated by 3alpha-reduced neurosteroids

31 March 2020

1 reference

Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis

31 March 2020

1 reference

Ro5-4864, a peripheral benzodiazepine receptor ligand, reduces reactive gliosis and protects hippocampal hilar neurons from kainic acid excitotoxicity.

31 March 2020

1 reference

Neuroprotective effect of Ro5-4864 following brain injury

31 March 2020

1 reference

Development of ligands for the peripheral benzodiazepine receptor

31 March 2020

1 reference

Diazepam neuroprotection in excitotoxic and oxidative stress involves a mitochondrial mechanism additional to the GABAAR and hypothermic effects.

31 March 2020

1 reference

Involvement of peripheral benzodiazepine receptor in the oxidative stress, death-signaling pathways, and renal injury induced by ischemia-reperfusion

31 March 2020

1 reference

The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development

31 March 2020

1 reference

Induction of liver microsomal cytochrome P-450 isozymes by 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline carboxamide

31 March 2020

1 reference

31 March 2020

Peripheral regeneration

1 reference

Anti-inflammatory effects of peripheral benzodiazepine receptor ligands in two mouse models of inflammation

31 March 2020

1 reference

Peripheral type benzodiazepine binding sites as a tool for the detection and quantification of CNS injury

31 March 2020

1 reference

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

31 March 2020

1 reference

Brain inflammation and adult neurogenesis: the dual role of microglia

31 March 2020

1 reference

Why does remyelination fail in multiple sclerosis?

31 March 2020

1 reference

Debris clearance by microglia: an essential link between degeneration and regeneration.

31 March 2020

1 reference

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

31 March 2020

1 reference

Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum

31 March 2020

1 reference

Translocator protein 18 kDa is involved in the regulation of reactive gliosis

31 March 2020

1 reference

TSPO over-expression increases motility, transmigration and proliferation properties of C6 rat glioma cells

31 March 2020

1 reference

PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor

31 March 2020

1 reference

Peripheral benzodiazepine receptor (PBR) ligand cytotoxicity unrelated to PBR expression

31 March 2020

1 reference

Modulation of tamoxifen-induced apoptosis by peripheral benzodiazepine receptor ligands in breast cancer cells

31 March 2020

1 reference

Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligand

31 March 2020

1 reference

Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106.

31 March 2020

1 reference

2-Phenyl-imidazo[1,2-a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats.

31 March 2020

1 reference

Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABAA receptor activity

31 March 2020

1 reference

Lack of tolerance to anxiolysis and withdrawal symptoms in mice repeatedly treated with AC-5216, a selective TSPO ligand

31 March 2020

1 reference

Imaging the peripheral benzodiazepine receptor response in central nervous system demyelination and remyelination

31 March 2020

1 reference

Imaging brain inflammation with [(11)C]PK11195 by PET and induction of the peripheral-type benzodiazepine receptor after transient focal ischemia in rats

31 March 2020

1 reference

The peripheral-type benzodiazepine receptor is involved in control of Ca2+-induced permeability transition pore opening in rat brain mitochondria

31 March 2020

1 reference

Platelet-activating factor induces permeability transition and cytochrome c release in isolated brain mitochondria

31 March 2020

1 reference

Peripheral benzodiazepine receptor-induced myocardial protection is mediated by inhibition of mitochondrial membrane permeabilization

31 March 2020

1 reference

Identification of des-(Gly-Ile)-endozepine as an effector of corticotropin-dependent adrenal steroidogenesis: stimulation of cholesterol delivery is mediated by the peripheral benzodiazepine receptor

31 March 2020

1 reference

Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives

31 March 2020

1 reference

Neurosteroid metabolism in the human brain

31 March 2020

1 reference

Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor

31 March 2020

1 reference

Activation of peripheral mitochondrial benzodiazepine receptors in the hippocampus stimulates allopregnanolone synthesis and produces anxiolytic-like effects in the rat.

31 March 2020

1 reference

Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo

31 March 2020

1 reference

Inflammatory Pain Upregulates Spinal Inhibition via Endogenous Neurosteroid Production

31 March 2020

1 reference

Regional differences in the decay kinetics of GABA(A) receptor-mediated miniature IPSCs in the dorsal horn of the rat spinal cord are determined by mitochondrial transport of cholesterol.

31 March 2020

1 reference

Neuroactive steroid regulation of neurotransmitter release in the CNS: action, mechanism and possible significance

31 March 2020

1 reference

Neurosteroids: endogenous allosteric modulators of GABA(A) receptors.

31 March 2020

1 reference

Progesterone 5-alpha-reduction in neuronal and in different types of glial cell cultures: type 1 and 2 astrocytes and oligodendrocytes

31 March 2020

1 reference

The 5alpha-reductase in the central nervous system: expression and modes of control

31 March 2020

1 reference

Topography and function of androgen-metabolizing enzymes in the central nervous system

31 March 2020

1 reference

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis

31 March 2020

1 reference

The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging

31 March 2020

1 reference

Extrasynaptic GABAA receptors of thalamocortical neurons: a molecular target for hypnotics.

31 March 2020

1 reference

Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors

31 March 2020

1 reference

GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol

31 March 2020

1 reference

Formation and plasticity of GABAergic synapses: physiological mechanisms and pathophysiological implications.

31 March 2020

1 reference

Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus?

31 March 2020

1 reference

The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells.

31 March 2020

1 reference

Extrasynaptic alphabeta subunit GABAA receptors on rat hippocampal pyramidal neurons.

31 March 2020

1 reference

Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones.

31 March 2020

1 reference

Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit.

31 March 2020

1 reference

Novel compounds selectively enhance delta subunit containing GABA A receptors and increase tonic currents in thalamus

31 March 2020

1 reference

Input-dependent synaptic targeting of alpha(2)-subunit-containing GABA(A) receptors in synapses of hippocampal pyramidal cells of the rat.

31 March 2020

1 reference

Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

31 March 2020

1 reference

GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids

31 March 2020

1 reference

Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.

31 March 2020

1 reference

Evaluation of protein docking predictions using Hex 3.1 in CAPRI rounds 1 and 2.

31 March 2020

1 reference

Structure and lipid transport mechanism of a StAR-related domain

31 March 2020

1 reference

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

31 March 2020

1 reference

Structural basis for the conformational adaptability of apolipophorin III, a helix-bundle exchangeable apolipoprotein

31 March 2020

1 reference

Synthesis, labeling, and biological evaluation of halogenated 2-quinolinecarboxamides as potential radioligands for the visualization of peripheral benzodiazepine receptors

31 March 2020

1 reference

N,N-dialkyl-2-phenylindol-3-ylglyoxylamides. A new class of potent and selective ligands at the peripheral benzodiazepine receptor.

31 March 2020

1 reference

Effects of Vinpocetine on mitochondrial function and neuroprotection in primary cortical neurons

31 March 2020

1 reference

[11C]vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies

31 March 2020

1 reference

Involvement of Peripheral-Type Benzodiazepine Receptors in the Intracellular Transport of Heme and Porphyrins1

31 March 2020

1 reference

Protoporphyrin IX binding and transport by recombinant mouse PBR.

31 March 2020

1 reference

Structure-function of human 3 alpha-hydroxysteroid dehydrogenases: genes and proteins.

31 March 2020

1 reference

Neurosteroids: endogenous regulators of the GABA(A) receptor

31 March 2020

1 reference

Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

31 March 2020

1 reference

Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites

31 March 2020

1 reference

Neurosteroids shift partial agonist activation of GABA(A) receptor channels from low- to high-efficacy gating patterns.

31 March 2020

1 reference

Subunit dependent modulation of GABAA receptor function by neuroactive steroids

31 March 2020

1 reference

The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors

31 March 2020

1 reference

Identification, localization, and function in steroidogenesis of PAP7: a peripheral-type benzodiazepine receptor- and PKA (RIalpha)-associated protein

31 March 2020

1 reference

12 December 2020

Peripheral benzodiazepine receptor ligands reverse apoptosis resistance of cancer cells in vitro and in vivo.

1 reference

12 December 2020

Neurosteroid progesterone is up-regulated in the brain of jimpy and shiverer mice.

1 reference

12 December 2020

Site-directed mutagenesis of the peripheral benzodiazepine receptor: identification of amino acids implicated in the binding site of Ro5-4864

1 reference

12 December 2020

PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis

1 reference

12 December 2020

2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR)

1 reference

12 December 2020

Ligands of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed to erucylphosphohomocholine

1 reference

12 December 2020

[Fatal subfulminant hepatitis during treatment with alpidem (Ananxyl)]

1 reference

12 December 2020

Stimulation of brain steroidogenesis by 2-aryl-indole-3-acetamide derivatives acting at the mitochondrial diazepam-binding inhibitor receptor complex

1 reference

12 December 2020

The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane.

1 reference

12 December 2020

Zolpidem and alpidem: two imidazopyridines with selectivity for omega 1- and omega 3-receptor subtypes.

1 reference

12 December 2020

Hepatitis induced by alpidem (Ananxyl). Four cases, one of them fatal

1 reference

12 December 2020

Peripheral benzodiazepine receptor: characterization in human T-lymphoma Jurkat cells

1 reference

12 December 2020

Mitochondrial benzodiazepine receptors mediate inhibition of mitochondrial respiratory control

1 reference

12 December 2020

Subfulminant hepatitis caused by alpidem and treated by liver transplantation

1 reference

12 December 2020

Enigma of the peripheral benzodiazepine receptor

1 reference

12 December 2020

The polypeptide diazepam-binding inhibitor and a higher affinity mitochondrial peripheral-type benzodiazepine receptor sustain constitutive steroidogenesis in the R2C Leydig tumor cell line

1 reference

12 December 2020

In vitro reconstitution of a functional peripheral-type benzodiazepine receptor from mouse Leydig tumor cells.

1 reference

12 December 2020

Diazepam binding inhibitor peptide: Cloning and gene expression

1 reference

12 December 2020

Regulation of the expression of peripheral benzodiazepine receptors and their endogenous ligands during rat sciatic nerve degeneration and regeneration: a role for PBR in neurosteroidogenesis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRD3295

1 reference

23 August 2017

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